Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058707450> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2058707450 endingPage "183" @default.
- W2058707450 startingPage "177" @default.
- W2058707450 abstract "Ultraviolet-irradiated Escherichia coli K12 uvrA(B,C) cells show higher survival if plated on minimal growth medium (MM) rather than on rich growth medium (RM). This phenomenon has been referred to as 'minimal medium recovery' (MMR). UV-irradiated (4 J/m2) uvrA cells showed a similar rate of protein synthesis, whether incubated in MM or RM, however, they showed a severe depression in DNA synthesis when incubated in MM that lasted for about 30 min, and the normal rate of DNA synthesis was not reestablished until about 60 min after irradiation. When a sample of these same cells was switched to RM immediately after UV-irradiation, there was only a slight slowing of DNA synthesis, and the normal rate of synthesis was reestablished by 60 min. An additional mmrA mutation or growth retardation by valine blocked both this extra DNA synthesis in RM, and the inhibitory effect of RM on survival. These findings suggest that the absence of a marked delay in DNA synthesis observed in RM may be responsible for the inhibitory effect of RM on the survival of UV-irradiated excision-deficient cells. Two hypotheses, which are not mutually exclusive, are proposed and supported by data to explain why a fast rate of DNA synthesis after UV-irradiation partially inhibits postreplication repair and enhances cell lethality." @default.
- W2058707450 created "2016-06-24" @default.
- W2058707450 creator A5045746331 @default.
- W2058707450 creator A5066028149 @default.
- W2058707450 date "1985-09-01" @default.
- W2058707450 modified "2023-10-16" @default.
- W2058707450 title "A mechanism for rich-medium inhibition of the repair of daughter-strand gaps in the deoxyribonucleic acid of UV-irradiated Escherichia coli K12 uvrA" @default.
- W2058707450 cites W1535660392 @default.
- W2058707450 cites W1550991844 @default.
- W2058707450 cites W1617756874 @default.
- W2058707450 cites W1877003434 @default.
- W2058707450 cites W1978697852 @default.
- W2058707450 cites W1981847030 @default.
- W2058707450 cites W2016629226 @default.
- W2058707450 cites W2035261281 @default.
- W2058707450 cites W2047580672 @default.
- W2058707450 cites W2057183223 @default.
- W2058707450 cites W2078323025 @default.
- W2058707450 cites W2113568081 @default.
- W2058707450 cites W2119626376 @default.
- W2058707450 cites W2122059889 @default.
- W2058707450 cites W2157441188 @default.
- W2058707450 cites W2896819077 @default.
- W2058707450 cites W4235473418 @default.
- W2058707450 cites W4249057392 @default.
- W2058707450 doi "https://doi.org/10.1016/0167-8817(85)90008-2" @default.
- W2058707450 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3897844" @default.
- W2058707450 hasPublicationYear "1985" @default.
- W2058707450 type Work @default.
- W2058707450 sameAs 2058707450 @default.
- W2058707450 citedByCount "10" @default.
- W2058707450 countsByYear W20587074502022 @default.
- W2058707450 countsByYear W20587074502023 @default.
- W2058707450 crossrefType "journal-article" @default.
- W2058707450 hasAuthorship W2058707450A5045746331 @default.
- W2058707450 hasAuthorship W2058707450A5066028149 @default.
- W2058707450 hasConcept C104317684 @default.
- W2058707450 hasConcept C111337013 @default.
- W2058707450 hasConcept C121332964 @default.
- W2058707450 hasConcept C134935766 @default.
- W2058707450 hasConcept C143425029 @default.
- W2058707450 hasConcept C153911025 @default.
- W2058707450 hasConcept C185544564 @default.
- W2058707450 hasConcept C185592680 @default.
- W2058707450 hasConcept C2777108182 @default.
- W2058707450 hasConcept C547475151 @default.
- W2058707450 hasConcept C552990157 @default.
- W2058707450 hasConcept C55493867 @default.
- W2058707450 hasConcept C64241487 @default.
- W2058707450 hasConcept C86803240 @default.
- W2058707450 hasConceptScore W2058707450C104317684 @default.
- W2058707450 hasConceptScore W2058707450C111337013 @default.
- W2058707450 hasConceptScore W2058707450C121332964 @default.
- W2058707450 hasConceptScore W2058707450C134935766 @default.
- W2058707450 hasConceptScore W2058707450C143425029 @default.
- W2058707450 hasConceptScore W2058707450C153911025 @default.
- W2058707450 hasConceptScore W2058707450C185544564 @default.
- W2058707450 hasConceptScore W2058707450C185592680 @default.
- W2058707450 hasConceptScore W2058707450C2777108182 @default.
- W2058707450 hasConceptScore W2058707450C547475151 @default.
- W2058707450 hasConceptScore W2058707450C552990157 @default.
- W2058707450 hasConceptScore W2058707450C55493867 @default.
- W2058707450 hasConceptScore W2058707450C64241487 @default.
- W2058707450 hasConceptScore W2058707450C86803240 @default.
- W2058707450 hasIssue "2" @default.
- W2058707450 hasLocation W20587074501 @default.
- W2058707450 hasLocation W20587074502 @default.
- W2058707450 hasOpenAccess W2058707450 @default.
- W2058707450 hasPrimaryLocation W20587074501 @default.
- W2058707450 hasRelatedWork W1486141601 @default.
- W2058707450 hasRelatedWork W1555395060 @default.
- W2058707450 hasRelatedWork W1995310695 @default.
- W2058707450 hasRelatedWork W1997989647 @default.
- W2058707450 hasRelatedWork W2024666087 @default.
- W2058707450 hasRelatedWork W2036160631 @default.
- W2058707450 hasRelatedWork W2076437565 @default.
- W2058707450 hasRelatedWork W2211305535 @default.
- W2058707450 hasRelatedWork W2411487084 @default.
- W2058707450 hasRelatedWork W2964016823 @default.
- W2058707450 hasVolume "146" @default.
- W2058707450 isParatext "false" @default.
- W2058707450 isRetracted "false" @default.
- W2058707450 magId "2058707450" @default.
- W2058707450 workType "article" @default.