Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058720123> ?p ?o ?g. }
- W2058720123 endingPage "326" @default.
- W2058720123 startingPage "326" @default.
- W2058720123 abstract "• We reviewed the English-language literature over a 16-year period (1960 through 1976) on the subject of prophylaxis with systemic antibiotics in surgery. Trials in genitourinary and cardiovascular surgery were not reviewed. Our definition of prophylaxis is antibiotic administration in the absence of infection or contamination. Of 131 articles reporting clinical trials using systemic antibiotics for prophylaxis, only 24 met the criterion of an appropriately designed study that generated evaluable data. In these, systemic antibiotics were shown to be of value in reducing wound infections after abdominal and vaginal hysterectomy, cesarean section, biliary surgery, total hip replacement, and microneurosurgical craniotomy. Antibiotic prophylaxis was of no value in laparotomy and groin hernia repair. Patients undergoing any of 21 different operations did not benefit from prophylactic antibiotic administration, though study groups were too small or infection rates too low to allow for firm conclusions. In certain patients at high risk of infection, systemic prophylaxis is warranted. Future clinical studies must be designed as randomized, blinded, prospective trials, with antibiotics administered by a parenteral route beginning preoperatively. (<i>Arch Surg</i>112: 326-334, 1977)" @default.
- W2058720123 created "2016-06-24" @default.
- W2058720123 creator A5007000396 @default.
- W2058720123 creator A5063560591 @default.
- W2058720123 date "1977-03-01" @default.
- W2058720123 modified "2023-10-18" @default.
- W2058720123 title "Use of Systemic Antibiotics for Prophylaxis in Surgery" @default.
- W2058720123 cites W1492619157 @default.
- W2058720123 cites W1514272286 @default.
- W2058720123 cites W1540892544 @default.
- W2058720123 cites W1571577741 @default.
- W2058720123 cites W1572273459 @default.
- W2058720123 cites W1575917260 @default.
- W2058720123 cites W1594494020 @default.
- W2058720123 cites W1604801234 @default.
- W2058720123 cites W1606284148 @default.
- W2058720123 cites W1702228132 @default.
- W2058720123 cites W1763435050 @default.
- W2058720123 cites W178759613 @default.
- W2058720123 cites W1940187544 @default.
- W2058720123 cites W1970693536 @default.
- W2058720123 cites W1974307577 @default.
- W2058720123 cites W1976828403 @default.
- W2058720123 cites W1978811602 @default.
- W2058720123 cites W1987860193 @default.
- W2058720123 cites W1989105229 @default.
- W2058720123 cites W1992670356 @default.
- W2058720123 cites W1993469356 @default.
- W2058720123 cites W1994982596 @default.
- W2058720123 cites W1995269250 @default.
- W2058720123 cites W2000902780 @default.
- W2058720123 cites W2002164657 @default.
- W2058720123 cites W2002656883 @default.
- W2058720123 cites W2003194408 @default.
- W2058720123 cites W2004540768 @default.
- W2058720123 cites W2005775861 @default.
- W2058720123 cites W2006985014 @default.
- W2058720123 cites W2007575177 @default.
- W2058720123 cites W2010459382 @default.
- W2058720123 cites W2016016933 @default.
- W2058720123 cites W2017984100 @default.
- W2058720123 cites W2020800039 @default.
- W2058720123 cites W2024275427 @default.
- W2058720123 cites W2024888235 @default.
- W2058720123 cites W2029117891 @default.
- W2058720123 cites W2029624631 @default.
- W2058720123 cites W2033764963 @default.
- W2058720123 cites W2037156921 @default.
- W2058720123 cites W2038386697 @default.
- W2058720123 cites W204494915 @default.
- W2058720123 cites W2055215490 @default.
- W2058720123 cites W2056347698 @default.
- W2058720123 cites W2057379251 @default.
- W2058720123 cites W2057882030 @default.
- W2058720123 cites W2060491892 @default.
- W2058720123 cites W2076440337 @default.
- W2058720123 cites W2076760004 @default.
- W2058720123 cites W2080394960 @default.
- W2058720123 cites W2082669882 @default.
- W2058720123 cites W2088910980 @default.
- W2058720123 cites W2089029526 @default.
- W2058720123 cites W2089534822 @default.
- W2058720123 cites W2091315212 @default.
- W2058720123 cites W2092199450 @default.
- W2058720123 cites W2094453402 @default.
- W2058720123 cites W2102748540 @default.
- W2058720123 cites W2108700584 @default.
- W2058720123 cites W2128475293 @default.
- W2058720123 cites W2140002287 @default.
- W2058720123 cites W2141207561 @default.
- W2058720123 cites W2146340881 @default.
- W2058720123 cites W2153862706 @default.
- W2058720123 cites W2169490385 @default.
- W2058720123 cites W2204756048 @default.
- W2058720123 cites W2207768906 @default.
- W2058720123 cites W2237870820 @default.
- W2058720123 cites W2242854743 @default.
- W2058720123 cites W2268919569 @default.
- W2058720123 cites W2272610219 @default.
- W2058720123 cites W2290214398 @default.
- W2058720123 cites W2321458 @default.
- W2058720123 cites W2338776190 @default.
- W2058720123 cites W2394814828 @default.
- W2058720123 cites W2395752076 @default.
- W2058720123 cites W2398613010 @default.
- W2058720123 cites W2399068980 @default.
- W2058720123 cites W2400045437 @default.
- W2058720123 cites W2403045226 @default.
- W2058720123 cites W2403914797 @default.
- W2058720123 cites W2405793478 @default.
- W2058720123 cites W2406036083 @default.
- W2058720123 cites W2409287513 @default.
- W2058720123 cites W2409488899 @default.
- W2058720123 cites W2410325878 @default.
- W2058720123 cites W2411115821 @default.
- W2058720123 cites W2411349519 @default.
- W2058720123 cites W2412241498 @default.
- W2058720123 cites W2412452618 @default.