Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058735594> ?p ?o ?g. }
- W2058735594 endingPage "504" @default.
- W2058735594 startingPage "493" @default.
- W2058735594 abstract "In humans eicosapentaenoic acid can be converted to 3-series prostaglandins (PGF3 alpha, PGI3, and PGE3). Whether 3-series prostaglandins can protect the gastric mucosa from injury as effectively as their 2-series analogs is unknown. Therefore, we compared the protective effects of PGF3 alpha and PGF2 alpha against gross and microscopic gastric mucosal injury in rats. Animals received a subcutaneous injection of either PGF3 alpha or PGF2 alpha in doses ranging from 0 (vehicle) to 16.8 mumol/kg and 30 min later they received intragastric administration of 1 ml of absolute ethanol. Whether mucosal injury was assessed 60 min or 5 min after ethanol, PGF3 alpha was significantly less protective against ethanol-induced damage than PGF2 alpha. These findings indicate that the presence of a third double bond in the prostaglandin F molecule between carbons 17 and 18 markedly reduces the protective effects of this prostaglandin on the gastric mucosa." @default.
- W2058735594 created "2016-06-24" @default.
- W2058735594 creator A5008570414 @default.
- W2058735594 creator A5036058020 @default.
- W2058735594 creator A5087460616 @default.
- W2058735594 creator A5089683398 @default.
- W2058735594 date "1989-04-01" @default.
- W2058735594 modified "2023-09-25" @default.
- W2058735594 title "Effect of prostaglandin F3α on gastric mucosal injury by ethanol in rats: Comparison with prostaglandin F2α" @default.
- W2058735594 cites W1615012936 @default.
- W2058735594 cites W1691251612 @default.
- W2058735594 cites W1896328975 @default.
- W2058735594 cites W1969225894 @default.
- W2058735594 cites W1973014418 @default.
- W2058735594 cites W1984005711 @default.
- W2058735594 cites W2007698429 @default.
- W2058735594 cites W2008873477 @default.
- W2058735594 cites W2021877212 @default.
- W2058735594 cites W2054631446 @default.
- W2058735594 cites W2055173111 @default.
- W2058735594 cites W2056493048 @default.
- W2058735594 cites W2062874559 @default.
- W2058735594 cites W2063856128 @default.
- W2058735594 cites W2072222076 @default.
- W2058735594 cites W2075124374 @default.
- W2058735594 cites W2075381208 @default.
- W2058735594 cites W2076732912 @default.
- W2058735594 cites W2095298038 @default.
- W2058735594 cites W2148190114 @default.
- W2058735594 cites W4234711984 @default.
- W2058735594 cites W4292670990 @default.
- W2058735594 cites W4294576108 @default.
- W2058735594 doi "https://doi.org/10.1016/0090-6980(89)90098-1" @default.
- W2058735594 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2788297" @default.
- W2058735594 hasPublicationYear "1989" @default.
- W2058735594 type Work @default.
- W2058735594 sameAs 2058735594 @default.
- W2058735594 citedByCount "16" @default.
- W2058735594 countsByYear W20587355942015 @default.
- W2058735594 countsByYear W20587355942018 @default.
- W2058735594 countsByYear W20587355942019 @default.
- W2058735594 countsByYear W20587355942020 @default.
- W2058735594 crossrefType "journal-article" @default.
- W2058735594 hasAuthorship W2058735594A5008570414 @default.
- W2058735594 hasAuthorship W2058735594A5036058020 @default.
- W2058735594 hasAuthorship W2058735594A5087460616 @default.
- W2058735594 hasAuthorship W2058735594A5089683398 @default.
- W2058735594 hasConcept C126322002 @default.
- W2058735594 hasConcept C134018914 @default.
- W2058735594 hasConcept C141071460 @default.
- W2058735594 hasConcept C185592680 @default.
- W2058735594 hasConcept C19038510 @default.
- W2058735594 hasConcept C2775944032 @default.
- W2058735594 hasConcept C2776091944 @default.
- W2058735594 hasConcept C2776390293 @default.
- W2058735594 hasConcept C2777198256 @default.
- W2058735594 hasConcept C2777956040 @default.
- W2058735594 hasConcept C2779422922 @default.
- W2058735594 hasConcept C2780161600 @default.
- W2058735594 hasConcept C2780664492 @default.
- W2058735594 hasConcept C2781443798 @default.
- W2058735594 hasConcept C2909370928 @default.
- W2058735594 hasConcept C49453240 @default.
- W2058735594 hasConcept C543025807 @default.
- W2058735594 hasConcept C55493867 @default.
- W2058735594 hasConcept C64943373 @default.
- W2058735594 hasConcept C71924100 @default.
- W2058735594 hasConcept C98274493 @default.
- W2058735594 hasConceptScore W2058735594C126322002 @default.
- W2058735594 hasConceptScore W2058735594C134018914 @default.
- W2058735594 hasConceptScore W2058735594C141071460 @default.
- W2058735594 hasConceptScore W2058735594C185592680 @default.
- W2058735594 hasConceptScore W2058735594C19038510 @default.
- W2058735594 hasConceptScore W2058735594C2775944032 @default.
- W2058735594 hasConceptScore W2058735594C2776091944 @default.
- W2058735594 hasConceptScore W2058735594C2776390293 @default.
- W2058735594 hasConceptScore W2058735594C2777198256 @default.
- W2058735594 hasConceptScore W2058735594C2777956040 @default.
- W2058735594 hasConceptScore W2058735594C2779422922 @default.
- W2058735594 hasConceptScore W2058735594C2780161600 @default.
- W2058735594 hasConceptScore W2058735594C2780664492 @default.
- W2058735594 hasConceptScore W2058735594C2781443798 @default.
- W2058735594 hasConceptScore W2058735594C2909370928 @default.
- W2058735594 hasConceptScore W2058735594C49453240 @default.
- W2058735594 hasConceptScore W2058735594C543025807 @default.
- W2058735594 hasConceptScore W2058735594C55493867 @default.
- W2058735594 hasConceptScore W2058735594C64943373 @default.
- W2058735594 hasConceptScore W2058735594C71924100 @default.
- W2058735594 hasConceptScore W2058735594C98274493 @default.
- W2058735594 hasIssue "4" @default.
- W2058735594 hasLocation W20587355941 @default.
- W2058735594 hasLocation W20587355942 @default.
- W2058735594 hasOpenAccess W2058735594 @default.
- W2058735594 hasPrimaryLocation W20587355941 @default.
- W2058735594 hasRelatedWork W1968397413 @default.
- W2058735594 hasRelatedWork W2016034363 @default.
- W2058735594 hasRelatedWork W2056100207 @default.
- W2058735594 hasRelatedWork W2058735594 @default.