FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058757434> ?p ?o ?g. }

• W2058757434 endingPage "224" @default.
• W2058757434 startingPage "220" @default.
• W2058757434 abstract "Aneuploidy is frequently seen in leukemia and myelodysplasia (MDS) but was thought to be uncommon in aplastic anemia (AA). We examined marrow cells from 96 unselected patients with bone marrow failure syndromes to assess the frequency of undetected aneuploidy for chromosomes 7 and 8 by fluorescence in situ hybridization (FISH) as compared to routine cytogenetic analysis. Twenty-eight percent (27/96) of patients had an abnormal karyotype. FISH identified an additional 27 patients with undetected monosomy 7 or trisomy 8. Those patients with undetected monosomy 7 generally had a poor clinical outcome, suffering from lack of response to medical therapy or early death. In one AA/MDS patient with normal cytogenetics, FISH identified a large population of monosomy 7 cells, which clearly heralded a clinical relapse. In another patient, FISH studies were used to delineate instability of chromosome 8, with apparent disease progression from AA to MDS. We conclude that undetected aneuploidy exists in marrow cells of a significant percentage of patients with bone marrow failure syndromes." @default.
• W2058757434 created "2016-06-24" @default.
• W2058757434 creator A5060331249 @default.
• W2058757434 creator A5072063614 @default.
• W2058757434 creator A5076023005 @default.
• W2058757434 creator A5084036548 @default.
• W2058757434 creator A5085974329 @default.
• W2058757434 date "2004-01-01" @default.
• W2058757434 modified "2023-09-29" @default.
• W2058757434 title "Genomic instability in bone marrow failure syndromes" @default.
• W2058757434 cites W136049078 @default.
• W2058757434 cites W1494921380 @default.
• W2058757434 cites W187238933 @default.
• W2058757434 cites W196567407 @default.
• W2058757434 cites W1970972261 @default.
• W2058757434 cites W1981978962 @default.
• W2058757434 cites W2006178295 @default.
• W2058757434 cites W2006512434 @default.
• W2058757434 cites W2015881261 @default.
• W2058757434 cites W2033594330 @default.
• W2058757434 cites W2074908271 @default.
• W2058757434 cites W2091411292 @default.
• W2058757434 cites W2100946177 @default.
• W2058757434 cites W2120096461 @default.
• W2058757434 cites W4253916874 @default.
• W2058757434 doi "https://doi.org/10.1002/ajh.20101" @default.
• W2058757434 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15224355" @default.
• W2058757434 hasPublicationYear "2004" @default.
• W2058757434 type Work @default.
• W2058757434 sameAs 2058757434 @default.
• W2058757434 citedByCount "19" @default.
• W2058757434 countsByYear W20587574342012 @default.
• W2058757434 countsByYear W20587574342013 @default.
• W2058757434 countsByYear W20587574342018 @default.
• W2058757434 countsByYear W20587574342020 @default.
• W2058757434 countsByYear W20587574342023 @default.
• W2058757434 crossrefType "journal-article" @default.
• W2058757434 hasAuthorship W2058757434A5060331249 @default.
• W2058757434 hasAuthorship W2058757434A5072063614 @default.
• W2058757434 hasAuthorship W2058757434A5076023005 @default.
• W2058757434 hasAuthorship W2058757434A5084036548 @default.
• W2058757434 hasAuthorship W2058757434A5085974329 @default.
• W2058757434 hasBestOaLocation W20587574341 @default.
• W2058757434 hasConcept C104317684 @default.
• W2058757434 hasConcept C109159458 @default.
• W2058757434 hasConcept C109748351 @default.
• W2058757434 hasConcept C126322002 @default.
• W2058757434 hasConcept C140752955 @default.
• W2058757434 hasConcept C142724271 @default.
• W2058757434 hasConcept C143998085 @default.
• W2058757434 hasConcept C174475383 @default.
• W2058757434 hasConcept C2776229224 @default.
• W2058757434 hasConcept C2777542201 @default.
• W2058757434 hasConcept C2778461978 @default.
• W2058757434 hasConcept C2779142324 @default.
• W2058757434 hasConcept C2779672484 @default.
• W2058757434 hasConcept C2780007613 @default.
• W2058757434 hasConcept C2780365373 @default.
• W2058757434 hasConcept C2780525284 @default.
• W2058757434 hasConcept C28328180 @default.
• W2058757434 hasConcept C2908647359 @default.
• W2058757434 hasConcept C30481170 @default.
• W2058757434 hasConcept C53226629 @default.
• W2058757434 hasConcept C54355233 @default.
• W2058757434 hasConcept C71924100 @default.
• W2058757434 hasConcept C86803240 @default.
• W2058757434 hasConcept C99454951 @default.
• W2058757434 hasConceptScore W2058757434C104317684 @default.
• W2058757434 hasConceptScore W2058757434C109159458 @default.
• W2058757434 hasConceptScore W2058757434C109748351 @default.
• W2058757434 hasConceptScore W2058757434C126322002 @default.
• W2058757434 hasConceptScore W2058757434C140752955 @default.
• W2058757434 hasConceptScore W2058757434C142724271 @default.
• W2058757434 hasConceptScore W2058757434C143998085 @default.
• W2058757434 hasConceptScore W2058757434C174475383 @default.
• W2058757434 hasConceptScore W2058757434C2776229224 @default.
• W2058757434 hasConceptScore W2058757434C2777542201 @default.
• W2058757434 hasConceptScore W2058757434C2778461978 @default.
• W2058757434 hasConceptScore W2058757434C2779142324 @default.
• W2058757434 hasConceptScore W2058757434C2779672484 @default.
• W2058757434 hasConceptScore W2058757434C2780007613 @default.
• W2058757434 hasConceptScore W2058757434C2780365373 @default.
• W2058757434 hasConceptScore W2058757434C2780525284 @default.
• W2058757434 hasConceptScore W2058757434C28328180 @default.
• W2058757434 hasConceptScore W2058757434C2908647359 @default.
• W2058757434 hasConceptScore W2058757434C30481170 @default.
• W2058757434 hasConceptScore W2058757434C53226629 @default.
• W2058757434 hasConceptScore W2058757434C54355233 @default.
• W2058757434 hasConceptScore W2058757434C71924100 @default.
• W2058757434 hasConceptScore W2058757434C86803240 @default.
• W2058757434 hasConceptScore W2058757434C99454951 @default.
• W2058757434 hasIssue "3" @default.
• W2058757434 hasLocation W20587574341 @default.
• W2058757434 hasLocation W20587574342 @default.
• W2058757434 hasOpenAccess W2058757434 @default.
• W2058757434 hasPrimaryLocation W20587574341 @default.
• W2058757434 hasRelatedWork W1963497218 @default.
• W2058757434 hasRelatedWork W1974754966 @default.

• next