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• W2058761374 abstract "Abstract The criteria for a suitable experimental breast cancer model are discussed. Only one of a series of nine tumour systems initially studied, consistently showed early lymph node and late lung metastases and fulfilled the criteria. This mammary carcinoma (2661) was more fully characterized and was found to be non-antigenic following subcutaneous and intravenous immunity challenge tests. Size of the primary tumour as well as lymph node palpation were shown to be crude indexes for survival. Metastases formation gave rise to changes in lymphatic drainage pathways. Combination adjuvant chemotherapy increased the survival time in treated animals and produced a striking difference in patterns of metastases distribution. Results on immunity, surgery and chemotherapy in regard to this model are discussed." @default.
• W2058761374 created "2016-06-24" @default.
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• W2058761374 date "1977-06-01" @default.
• W2058761374 modified "2023-09-26" @default.
• W2058761374 title "A new metastasizing mammary carcinoma model in mice: Model characteristics and applications" @default.
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• W2058761374 doi "https://doi.org/10.1016/0014-2964(77)90117-7" @default.
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