FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058771505> ?p ?o ?g. }

• W2058771505 endingPage "1655" @default.
• W2058771505 startingPage "1649" @default.
• W2058771505 abstract "In order to enhance the sensitivity and the speed of the yeast estrogen screen (YES)-assay, which has been established in many laboratories for the determination of estrogenic activity of compounds and environmental samples, the LYES-assay, a modified version of the YES-assay including a digestion step with the enzyme lyticase, was developed. With the LYES-assay the estrogenic activities of natural (17beta-estradiol E2 and estrone), synthetic (17alpha-ethinylestradiol EE2) and pharmaceutical estrogens (diethylstilbestrol DES) as well as xenoestrogens (4-nonylphenol NP and five parabens) were determined and compared with the results obtained by other in vitro-assays namely the conventional YES-assay, the E-Screen-assay (MCF-7 breast tumor cell proliferation) and a receptor binding-assay (RB) with human estrogen receptors hER-alpha and hER-beta. In the case of E2 the LYES-assay had a significantly lower limit of quantification (LOQ) than the conventional YES-assay and even two orders of magnitude lower than the RB-assay. Compared to the E-Screen-assay the LOQ of the LYES-assay was almost one order of magnitude higher. The time required to perform the LYES-assay was as little as seven hours compared to three to five days for the conventional YES-assay. Thus, the LYES-assay is a very good alternative to existing estrogenic in vitro-assays, since it has a good sensitivity, is cheap and much faster than the other assays." @default.
• W2058771505 created "2016-06-24" @default.
• W2058771505 creator A5021774726 @default.
• W2058771505 creator A5023707001 @default.
• W2058771505 date "2004-12-01" @default.
• W2058771505 modified "2023-09-23" @default.
• W2058771505 title "Determination of estrogenic activity by LYES-assay (yeast estrogen screen-assay assisted by enzymatic digestion with lyticase)" @default.
• W2058771505 cites W167600473 @default.
• W2058771505 cites W1973446897 @default.
• W2058771505 cites W1991352044 @default.
• W2058771505 cites W1993455197 @default.
• W2058771505 cites W1997420299 @default.
• W2058771505 cites W2000160859 @default.
• W2058771505 cites W2011853672 @default.
• W2058771505 cites W2017125438 @default.
• W2058771505 cites W2034706088 @default.
• W2058771505 cites W2042124938 @default.
• W2058771505 cites W2049495967 @default.
• W2058771505 cites W2053284137 @default.
• W2058771505 cites W2071497567 @default.
• W2058771505 cites W2073417234 @default.
• W2058771505 cites W2086468341 @default.
• W2058771505 cites W2095718513 @default.
• W2058771505 cites W2158916245 @default.
• W2058771505 doi "https://doi.org/10.1016/j.chemosphere.2004.06.027" @default.
• W2058771505 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15519410" @default.
• W2058771505 hasPublicationYear "2004" @default.
• W2058771505 type Work @default.
• W2058771505 sameAs 2058771505 @default.
• W2058771505 citedByCount "81" @default.
• W2058771505 countsByYear W20587715052012 @default.
• W2058771505 countsByYear W20587715052013 @default.
• W2058771505 countsByYear W20587715052014 @default.
• W2058771505 countsByYear W20587715052015 @default.
• W2058771505 countsByYear W20587715052016 @default.
• W2058771505 countsByYear W20587715052017 @default.
• W2058771505 countsByYear W20587715052018 @default.
• W2058771505 countsByYear W20587715052019 @default.
• W2058771505 countsByYear W20587715052020 @default.
• W2058771505 countsByYear W20587715052021 @default.
• W2058771505 countsByYear W20587715052022 @default.
• W2058771505 crossrefType "journal-article" @default.
• W2058771505 hasAuthorship W2058771505A5021774726 @default.
• W2058771505 hasAuthorship W2058771505A5023707001 @default.
• W2058771505 hasConcept C104488531 @default.
• W2058771505 hasConcept C107872376 @default.
• W2058771505 hasConcept C119128265 @default.
• W2058771505 hasConcept C121608353 @default.
• W2058771505 hasConcept C134018914 @default.
• W2058771505 hasConcept C142724271 @default.
• W2058771505 hasConcept C153911025 @default.
• W2058771505 hasConcept C170493617 @default.
• W2058771505 hasConcept C181199279 @default.
• W2058771505 hasConcept C185592680 @default.
• W2058771505 hasConcept C202751555 @default.
• W2058771505 hasConcept C204787440 @default.
• W2058771505 hasConcept C2777164284 @default.
• W2058771505 hasConcept C2778656385 @default.
• W2058771505 hasConcept C2779272402 @default.
• W2058771505 hasConcept C2780155452 @default.
• W2058771505 hasConcept C2780367336 @default.
• W2058771505 hasConcept C2781397067 @default.
• W2058771505 hasConcept C43617362 @default.
• W2058771505 hasConcept C530470458 @default.
• W2058771505 hasConcept C54355233 @default.
• W2058771505 hasConcept C55493867 @default.
• W2058771505 hasConcept C71315377 @default.
• W2058771505 hasConcept C71924100 @default.
• W2058771505 hasConcept C84606932 @default.
• W2058771505 hasConcept C85196483 @default.
• W2058771505 hasConcept C86803240 @default.
• W2058771505 hasConceptScore W2058771505C104488531 @default.
• W2058771505 hasConceptScore W2058771505C107872376 @default.
• W2058771505 hasConceptScore W2058771505C119128265 @default.
• W2058771505 hasConceptScore W2058771505C121608353 @default.
• W2058771505 hasConceptScore W2058771505C134018914 @default.
• W2058771505 hasConceptScore W2058771505C142724271 @default.
• W2058771505 hasConceptScore W2058771505C153911025 @default.
• W2058771505 hasConceptScore W2058771505C170493617 @default.
• W2058771505 hasConceptScore W2058771505C181199279 @default.
• W2058771505 hasConceptScore W2058771505C185592680 @default.
• W2058771505 hasConceptScore W2058771505C202751555 @default.
• W2058771505 hasConceptScore W2058771505C204787440 @default.
• W2058771505 hasConceptScore W2058771505C2777164284 @default.
• W2058771505 hasConceptScore W2058771505C2778656385 @default.
• W2058771505 hasConceptScore W2058771505C2779272402 @default.
• W2058771505 hasConceptScore W2058771505C2780155452 @default.
• W2058771505 hasConceptScore W2058771505C2780367336 @default.
• W2058771505 hasConceptScore W2058771505C2781397067 @default.
• W2058771505 hasConceptScore W2058771505C43617362 @default.
• W2058771505 hasConceptScore W2058771505C530470458 @default.
• W2058771505 hasConceptScore W2058771505C54355233 @default.
• W2058771505 hasConceptScore W2058771505C55493867 @default.
• W2058771505 hasConceptScore W2058771505C71315377 @default.
• W2058771505 hasConceptScore W2058771505C71924100 @default.
• W2058771505 hasConceptScore W2058771505C84606932 @default.
• W2058771505 hasConceptScore W2058771505C85196483 @default.
• W2058771505 hasConceptScore W2058771505C86803240 @default.

• next