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- W2058779664 abstract "Plasma membranes isolated from a yeast sterol auxotroph (RD5-R) grown on 1, 5, and 15 μg ml−1 exogenous concentrations of sterol showed no discontinuity in plots of steady-state fluorescence anisotropy. Liposomes constructed from phospholipid and sterol extracted from RD5-R grown on different sterols indicated that exogenously supplied sterol modulated cellular phospholipids such that lipid-phase transitions were avoided. Liposomes derived from sterol and phospholipid extracted from the same culture exhibited no lipid-phase transitions. However, when phospholipid extracted from a culture grown on a specific sterol was mixed with sterol extracted from a heterologous culture grown on a different sterol to form liposomes, discontinuities were detected in the anisotropy measurements of the liposomes produced. Quantitative analyses revealed that the exogenously supplied sterol coordinately regulated specific phospholipid species, fatty acid composition, and sterol to phospholipid ratios in yeast auxotrophs." @default.
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- W2058779664 date "1985-08-01" @default.
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- W2058779664 title "Modulation of yeast plasma membrane composition of a yeast sterol auxotroph as a function of exogenous sterol" @default.
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- W2058779664 doi "https://doi.org/10.1016/0003-9861(85)90059-1" @default.
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