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- W2058794146 abstract "The effect of erythrityl tetranitrate administered sublingually in a dose of 15 mg. was evaluated in 43 patients with angina pectoris by means of radioelectrocardiography. Leads ii, V4 and V6 were telemetered successively for 10 sec. each throughout the test and one, three and five minutes after cessation of the exercise in the standing position. The type and amount of exercise performed was similar to that of the standardized double (Master) two-step exercise test. Of the 43 patients included in this study, 29 (Group A) showed definite electrocardiographic alterations during the control exercise test, 11 (Group B) revealed minor or equivocal changes, and 3 (Group C) exhibited no electrocardiographic alterations, but severe chest pain developed during the control test. Forty-five minutes after administration of erythrityl tetranitrate the exercise tests were repeated under similar conditions. Twenty-six of the 40 patients (65 per cent) with electrocardiographic changes during the control test showed improvement in their tracings during the repeat test. In 18 of 19 patients (95%) who experienced chest pain during the control test, the pain failed to occur after administration of erythrityl tetranitrate. Nineteen of 25 patients (75%) with definite depressions of the S-T segment during the control exercise test showed improvement after erythrityl tetranitrate; in contrast, only 6 of 11 patients (55%) with minor S-T or T changes were improved. Placebos given to 20 patients had no effect on the electrocardiographic alterations." @default.
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- W2058794146 date "1963-05-01" @default.
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- W2058794146 title "Effect of erythrityl tetranitrate on the electrocardiogram as recorded during exercise by radioelectrocardiography" @default.
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- W2058794146 doi "https://doi.org/10.1016/0002-9149(63)90079-1" @default.
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