Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058802170> ?p ?o ?g. }
- W2058802170 endingPage "82" @default.
- W2058802170 startingPage "76" @default.
- W2058802170 abstract "Mouse models of breast cancer, especially transgenic and knockout mice, have been established as valuable tools in shedding light on factors involved in preneoplastic changes, tumor development and malignant progression. The majority of mouse transgenic models develop estrogen receptor (ER) negative tumors. This is seen as a drawback because the majority of human breast cancers present an ER positive phenotype. On the other hand, several transgenic mouse models have been developed that produce ER positive mammary tumors. These include mice over-expressing aromatase, ERα, PELP-1 and AIB-1. In this review, we will discuss the value of these models as physiologically relevant in vivo systems to understand breast cancer as well as some of the pitfalls involving these models. In all, we argue that the use of transgenic models has improved our understanding of the molecular aspects and biology of breast cancer." @default.
- W2058802170 created "2016-06-24" @default.
- W2058802170 creator A5031605337 @default.
- W2058802170 creator A5054763940 @default.
- W2058802170 date "2012-09-01" @default.
- W2058802170 modified "2023-09-27" @default.
- W2058802170 title "Transgenic mouse models of hormonal mammary carcinogenesis: Advantages and limitations" @default.
- W2058802170 cites W1508838109 @default.
- W2058802170 cites W1523335221 @default.
- W2058802170 cites W1526579036 @default.
- W2058802170 cites W1832716426 @default.
- W2058802170 cites W1927418190 @default.
- W2058802170 cites W192986845 @default.
- W2058802170 cites W1965657782 @default.
- W2058802170 cites W1966935008 @default.
- W2058802170 cites W1967468131 @default.
- W2058802170 cites W1969070090 @default.
- W2058802170 cites W1975892924 @default.
- W2058802170 cites W1985193538 @default.
- W2058802170 cites W1987574507 @default.
- W2058802170 cites W2001116848 @default.
- W2058802170 cites W2001679453 @default.
- W2058802170 cites W2005139796 @default.
- W2058802170 cites W2006982410 @default.
- W2058802170 cites W2010040980 @default.
- W2058802170 cites W2011925462 @default.
- W2058802170 cites W2012425172 @default.
- W2058802170 cites W2015996293 @default.
- W2058802170 cites W2018552063 @default.
- W2058802170 cites W2019004723 @default.
- W2058802170 cites W2022158682 @default.
- W2058802170 cites W2025702732 @default.
- W2058802170 cites W2025943139 @default.
- W2058802170 cites W2032338743 @default.
- W2058802170 cites W2035040442 @default.
- W2058802170 cites W2042776634 @default.
- W2058802170 cites W2044451252 @default.
- W2058802170 cites W2055773511 @default.
- W2058802170 cites W2056386587 @default.
- W2058802170 cites W2057845792 @default.
- W2058802170 cites W2062932571 @default.
- W2058802170 cites W2072171958 @default.
- W2058802170 cites W2074900170 @default.
- W2058802170 cites W2079532726 @default.
- W2058802170 cites W2084602777 @default.
- W2058802170 cites W2085921275 @default.
- W2058802170 cites W2089258206 @default.
- W2058802170 cites W2090453278 @default.
- W2058802170 cites W2094906472 @default.
- W2058802170 cites W2098103041 @default.
- W2058802170 cites W2098294628 @default.
- W2058802170 cites W2100323988 @default.
- W2058802170 cites W2100401891 @default.
- W2058802170 cites W2101054534 @default.
- W2058802170 cites W2109203614 @default.
- W2058802170 cites W2109525253 @default.
- W2058802170 cites W2110869504 @default.
- W2058802170 cites W2111253687 @default.
- W2058802170 cites W2112159778 @default.
- W2058802170 cites W2116010079 @default.
- W2058802170 cites W2117357260 @default.
- W2058802170 cites W2119867844 @default.
- W2058802170 cites W2120486784 @default.
- W2058802170 cites W2121656289 @default.
- W2058802170 cites W2126990159 @default.
- W2058802170 cites W2127992009 @default.
- W2058802170 cites W2128242453 @default.
- W2058802170 cites W2129311237 @default.
- W2058802170 cites W2139746114 @default.
- W2058802170 cites W2143283599 @default.
- W2058802170 cites W2143675738 @default.
- W2058802170 cites W2148253831 @default.
- W2058802170 cites W2148570851 @default.
- W2058802170 cites W2150081723 @default.
- W2058802170 cites W2152098404 @default.
- W2058802170 cites W2155239200 @default.
- W2058802170 cites W2155871333 @default.
- W2058802170 cites W2156873226 @default.
- W2058802170 cites W2157945909 @default.
- W2058802170 cites W2167787018 @default.
- W2058802170 cites W2169422186 @default.
- W2058802170 cites W2327258659 @default.
- W2058802170 cites W72372646 @default.
- W2058802170 doi "https://doi.org/10.1016/j.jsbmb.2011.11.005" @default.
- W2058802170 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22119744" @default.
- W2058802170 hasPublicationYear "2012" @default.
- W2058802170 type Work @default.
- W2058802170 sameAs 2058802170 @default.
- W2058802170 citedByCount "9" @default.
- W2058802170 countsByYear W20588021702012 @default.
- W2058802170 countsByYear W20588021702013 @default.
- W2058802170 countsByYear W20588021702014 @default.
- W2058802170 countsByYear W20588021702015 @default.
- W2058802170 countsByYear W20588021702017 @default.
- W2058802170 countsByYear W20588021702020 @default.
- W2058802170 countsByYear W20588021702023 @default.
- W2058802170 crossrefType "journal-article" @default.
- W2058802170 hasAuthorship W2058802170A5031605337 @default.