FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058873359> ?p ?o ?g. }

• W2058873359 endingPage "1047" @default.
• W2058873359 startingPage "1039" @default.
• W2058873359 abstract "Background. Approaches to interpretation of quality of life changes in clinical trials have fallen into two camps: those that rely on the distribution of changes and the Effect Size (ES), and those that use some external anchor, such as patient judgments of change, which is then used to compute a Minimally Important Difference (MID), the proportion benefiting from treatment, p(B), and the Number Needed to Treat (NNT). Objective. To examine the relationship between the ES and p(B), and the impact of the MID on this relationship. Methods. Simulation was used based on a normal distribution to compute the proportion of patients benefiting in both parallel group and crossover designs, for various values of the ES and the MID. The agreement of the simulation with empirical data from four studies of asthma and respiratory disease was assessed. The effect of skewness in the distributions of change scores on the relationship between ES and p(B) was also examined. Results. The simulation showed a near-linear relationship between ES and p(B), which was nearly independent of the value of the MID. Agreement of the simulation with the empirical data were excellent. Although the curves differed for crossover and parallel group designs, the general form was similar. Introducing moderate skew into the distributions had minimal impact on the relationship. Conclusions. The proportion of patients who will benefit from treatment can be directly estimated from the ES, and is nearly independent of the choice of MID. Effect size and anchor based approaches provide equivalent information in this situation." @default.
• W2058873359 created "2016-06-24" @default.
• W2058873359 creator A5010582683 @default.
• W2058873359 creator A5026151229 @default.
• W2058873359 creator A5031717153 @default.
• W2058873359 creator A5070476857 @default.
• W2058873359 date "2001-10-01" @default.
• W2058873359 modified "2023-10-18" @default.
• W2058873359 title "Relation of Distribution- and Anchor-Based Approaches in Interpretation of Changes in Health-Related Quality of Life" @default.
• W2058873359 cites W1583848026 @default.
• W2058873359 cites W1967126262 @default.
• W2058873359 cites W1987445308 @default.
• W2058873359 cites W2020305363 @default.
• W2058873359 cites W2036379170 @default.
• W2058873359 cites W2041369332 @default.
• W2058873359 cites W2041853216 @default.
• W2058873359 cites W2087760311 @default.
• W2058873359 cites W2091241810 @default.
• W2058873359 cites W2097667004 @default.
• W2058873359 cites W2113163333 @default.
• W2058873359 cites W2125961419 @default.
• W2058873359 cites W2139073281 @default.
• W2058873359 cites W2155286376 @default.
• W2058873359 cites W2917045438 @default.
• W2058873359 cites W4235813114 @default.
• W2058873359 doi "https://doi.org/10.1097/00005650-200110000-00002" @default.
• W2058873359 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11567167" @default.
• W2058873359 hasPublicationYear "2001" @default.
• W2058873359 type Work @default.
• W2058873359 sameAs 2058873359 @default.
• W2058873359 citedByCount "241" @default.
• W2058873359 countsByYear W20588733592012 @default.
• W2058873359 countsByYear W20588733592013 @default.
• W2058873359 countsByYear W20588733592014 @default.
• W2058873359 countsByYear W20588733592015 @default.
• W2058873359 countsByYear W20588733592016 @default.
• W2058873359 countsByYear W20588733592017 @default.
• W2058873359 countsByYear W20588733592018 @default.
• W2058873359 countsByYear W20588733592019 @default.
• W2058873359 countsByYear W20588733592020 @default.
• W2058873359 countsByYear W20588733592021 @default.
• W2058873359 countsByYear W20588733592022 @default.
• W2058873359 countsByYear W20588733592023 @default.
• W2058873359 crossrefType "journal-article" @default.
• W2058873359 hasAuthorship W2058873359A5010582683 @default.
• W2058873359 hasAuthorship W2058873359A5026151229 @default.
• W2058873359 hasAuthorship W2058873359A5031717153 @default.
• W2058873359 hasAuthorship W2058873359A5070476857 @default.
• W2058873359 hasConcept C105795698 @default.
• W2058873359 hasConcept C110121322 @default.
• W2058873359 hasConcept C111472728 @default.
• W2058873359 hasConcept C122342681 @default.
• W2058873359 hasConcept C122507166 @default.
• W2058873359 hasConcept C134306372 @default.
• W2058873359 hasConcept C138885662 @default.
• W2058873359 hasConcept C149782125 @default.
• W2058873359 hasConcept C154945302 @default.
• W2058873359 hasConcept C159110408 @default.
• W2058873359 hasConcept C199360897 @default.
• W2058873359 hasConcept C2779530757 @default.
• W2058873359 hasConcept C2779951463 @default.
• W2058873359 hasConcept C33923547 @default.
• W2058873359 hasConcept C41008148 @default.
• W2058873359 hasConcept C43711488 @default.
• W2058873359 hasConcept C527412718 @default.
• W2058873359 hasConcept C71924100 @default.
• W2058873359 hasConcept C76155785 @default.
• W2058873359 hasConceptScore W2058873359C105795698 @default.
• W2058873359 hasConceptScore W2058873359C110121322 @default.
• W2058873359 hasConceptScore W2058873359C111472728 @default.
• W2058873359 hasConceptScore W2058873359C122342681 @default.
• W2058873359 hasConceptScore W2058873359C122507166 @default.
• W2058873359 hasConceptScore W2058873359C134306372 @default.
• W2058873359 hasConceptScore W2058873359C138885662 @default.
• W2058873359 hasConceptScore W2058873359C149782125 @default.
• W2058873359 hasConceptScore W2058873359C154945302 @default.
• W2058873359 hasConceptScore W2058873359C159110408 @default.
• W2058873359 hasConceptScore W2058873359C199360897 @default.
• W2058873359 hasConceptScore W2058873359C2779530757 @default.
• W2058873359 hasConceptScore W2058873359C2779951463 @default.
• W2058873359 hasConceptScore W2058873359C33923547 @default.
• W2058873359 hasConceptScore W2058873359C41008148 @default.
• W2058873359 hasConceptScore W2058873359C43711488 @default.
• W2058873359 hasConceptScore W2058873359C527412718 @default.
• W2058873359 hasConceptScore W2058873359C71924100 @default.
• W2058873359 hasConceptScore W2058873359C76155785 @default.
• W2058873359 hasIssue "10" @default.
• W2058873359 hasLocation W20588733591 @default.
• W2058873359 hasLocation W20588733592 @default.
• W2058873359 hasOpenAccess W2058873359 @default.
• W2058873359 hasPrimaryLocation W20588733591 @default.
• W2058873359 hasRelatedWork W1622180344 @default.
• W2058873359 hasRelatedWork W2099138829 @default.
• W2058873359 hasRelatedWork W2785616772 @default.
• W2058873359 hasRelatedWork W2896097814 @default.
• W2058873359 hasRelatedWork W2913537149 @default.
• W2058873359 hasRelatedWork W3082395339 @default.
• W2058873359 hasRelatedWork W3087516072 @default.

• next