FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058908849> ?p ?o ?g. }

• W2058908849 endingPage "784" @default.
• W2058908849 startingPage "781" @default.
• W2058908849 abstract "The epigenetic contribution to the regulation and maintenance of gene expression patterns by histone modifications is well established in eukaryotes. In Plasmodium falciparum, the mechanisms and factors regulating gene expression during progression through its infected red blood cell cycle (iRBC) and underlying mutually exclusive expression of antigenic variation genes involved in immune evasion are far from understood. Recently, the first comprehensive analyses of the P. falciparum chromatin landscape at different iRBC stages have been performed. These studies uncovered the existence of well-defined heterochromatic regions within a generally euchromatic epigenome. Notably, silencing of genes encoding for virulence determinants such as var genes, appears to be orchestrated by the concerted action of the Sir2 and HP1 orthologs and the presence of the histone mark, H3K9me3. Epigenetic speciation could make the parasite exquisitely vulnerable to epigenetic drug treatment, unless this deadly parasite still has a number of tricks up his sleeves." @default.
• W2058908849 created "2016-06-24" @default.
• W2058908849 creator A5001853003 @default.
• W2058908849 creator A5036095832 @default.
• W2058908849 creator A5087874057 @default.
• W2058908849 creator A5091071900 @default.
• W2058908849 date "2010-06-01" @default.
• W2058908849 modified "2023-10-16" @default.
• W2058908849 title "Malaria: Could its unusual epigenome be the weak spot?" @default.
• W2058908849 cites W1974091218 @default.
• W2058908849 cites W1982531329 @default.
• W2058908849 cites W1989463861 @default.
• W2058908849 cites W1989988433 @default.
• W2058908849 cites W1999686286 @default.
• W2058908849 cites W2019770479 @default.
• W2058908849 cites W2024639033 @default.
• W2058908849 cites W2041036553 @default.
• W2058908849 cites W2047849307 @default.
• W2058908849 cites W2063123398 @default.
• W2058908849 cites W2087573417 @default.
• W2058908849 cites W2090128221 @default.
• W2058908849 cites W2096496718 @default.
• W2058908849 cites W2098103685 @default.
• W2058908849 cites W2101478195 @default.
• W2058908849 cites W2112047656 @default.
• W2058908849 cites W2117290286 @default.
• W2058908849 cites W2120085393 @default.
• W2058908849 cites W2126782356 @default.
• W2058908849 cites W2129897419 @default.
• W2058908849 cites W2134959466 @default.
• W2058908849 cites W2137171250 @default.
• W2058908849 cites W2141827783 @default.
• W2058908849 cites W2142523861 @default.
• W2058908849 cites W2149232833 @default.
• W2058908849 cites W2149991876 @default.
• W2058908849 cites W2154071457 @default.
• W2058908849 cites W2159407301 @default.
• W2058908849 cites W2107046226 @default.
• W2058908849 doi "https://doi.org/10.1016/j.biocel.2010.03.010" @default.
• W2058908849 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20303414" @default.
• W2058908849 hasPublicationYear "2010" @default.
• W2058908849 type Work @default.
• W2058908849 sameAs 2058908849 @default.
• W2058908849 citedByCount "22" @default.
• W2058908849 countsByYear W20589088492012 @default.
• W2058908849 countsByYear W20589088492013 @default.
• W2058908849 countsByYear W20589088492015 @default.
• W2058908849 countsByYear W20589088492016 @default.
• W2058908849 countsByYear W20589088492017 @default.
• W2058908849 countsByYear W20589088492019 @default.
• W2058908849 countsByYear W20589088492020 @default.
• W2058908849 countsByYear W20589088492022 @default.
• W2058908849 crossrefType "journal-article" @default.
• W2058908849 hasAuthorship W2058908849A5001853003 @default.
• W2058908849 hasAuthorship W2058908849A5036095832 @default.
• W2058908849 hasAuthorship W2058908849A5087874057 @default.
• W2058908849 hasAuthorship W2058908849A5091071900 @default.
• W2058908849 hasConcept C100924687 @default.
• W2058908849 hasConcept C103435993 @default.
• W2058908849 hasConcept C104317684 @default.
• W2058908849 hasConcept C117717151 @default.
• W2058908849 hasConcept C121912465 @default.
• W2058908849 hasConcept C150194340 @default.
• W2058908849 hasConcept C190727270 @default.
• W2058908849 hasConcept C191942190 @default.
• W2058908849 hasConcept C41091548 @default.
• W2058908849 hasConcept C54355233 @default.
• W2058908849 hasConcept C64927066 @default.
• W2058908849 hasConcept C83640560 @default.
• W2058908849 hasConcept C86803240 @default.
• W2058908849 hasConcept C92149661 @default.
• W2058908849 hasConceptScore W2058908849C100924687 @default.
• W2058908849 hasConceptScore W2058908849C103435993 @default.
• W2058908849 hasConceptScore W2058908849C104317684 @default.
• W2058908849 hasConceptScore W2058908849C117717151 @default.
• W2058908849 hasConceptScore W2058908849C121912465 @default.
• W2058908849 hasConceptScore W2058908849C150194340 @default.
• W2058908849 hasConceptScore W2058908849C190727270 @default.
• W2058908849 hasConceptScore W2058908849C191942190 @default.
• W2058908849 hasConceptScore W2058908849C41091548 @default.
• W2058908849 hasConceptScore W2058908849C54355233 @default.
• W2058908849 hasConceptScore W2058908849C64927066 @default.
• W2058908849 hasConceptScore W2058908849C83640560 @default.
• W2058908849 hasConceptScore W2058908849C86803240 @default.
• W2058908849 hasConceptScore W2058908849C92149661 @default.
• W2058908849 hasIssue "6" @default.
• W2058908849 hasLocation W20589088491 @default.
• W2058908849 hasLocation W20589088492 @default.
• W2058908849 hasOpenAccess W2058908849 @default.
• W2058908849 hasPrimaryLocation W20589088491 @default.
• W2058908849 hasRelatedWork W1506160043 @default.
• W2058908849 hasRelatedWork W2004315839 @default.
• W2058908849 hasRelatedWork W2058908849 @default.
• W2058908849 hasRelatedWork W2115656844 @default.
• W2058908849 hasRelatedWork W2167039756 @default.
• W2058908849 hasRelatedWork W2330707342 @default.
• W2058908849 hasRelatedWork W2966379217 @default.
• W2058908849 hasRelatedWork W3037857843 @default.

• next