FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058912845> ?p ?o ?g. }

• W2058912845 endingPage "1033" @default.
• W2058912845 startingPage "1030" @default.
• W2058912845 abstract "Unlike all vascular beds with the exception of the pulmonary circulation, fetoplacental vessels respond to acute hypoxia with vasoconstriction. While this hypoxic fetoplacental vasoconstriction (HFPV) is considered essential in the pathogenesis of intrauterine growth retardation, its mechanism is largely unknown. Hypoxia inhibits potassium channels and thus causes depolarization in fetoplacental vascular smooth muscle. We propose that this hypoxia-induced depolarization leads to vasoconstriction by activating voltage-dependent calcium (Ca) channels and Ca influx. We compared HFPV between isolated perfused human cotyledons treated with an inhibitor of L-type channels, nifedipine, and preparations receiving only vehicle. While the solvent (diluted DMSO) had no inhibitory effect on HFPV, the hypoxic responses were completely abolished even by a relatively low dose of nifedipine (1 nM). We conclude that activation of L-type Ca channels is an essential part of HFPV." @default.
• W2058912845 created "2016-06-24" @default.
• W2058912845 creator A5016527328 @default.
• W2058912845 creator A5026438725 @default.
• W2058912845 creator A5083856804 @default.
• W2058912845 date "2006-09-01" @default.
• W2058912845 modified "2023-09-27" @default.
• W2058912845 title "Voltage-gated Calcium Channels Mediate Hypoxic Vasoconstriction in the Human Placenta" @default.
• W2058912845 cites W1899877571 @default.
• W2058912845 cites W1951323910 @default.
• W2058912845 cites W1966284289 @default.
• W2058912845 cites W1969883174 @default.
• W2058912845 cites W1973033888 @default.
• W2058912845 cites W1986117743 @default.
• W2058912845 cites W2001223885 @default.
• W2058912845 cites W2001859539 @default.
• W2058912845 cites W2019345683 @default.
• W2058912845 cites W2039741690 @default.
• W2058912845 cites W2050099786 @default.
• W2058912845 cites W2076181757 @default.
• W2058912845 cites W2089288497 @default.
• W2058912845 cites W2102115309 @default.
• W2058912845 cites W2103857474 @default.
• W2058912845 cites W2117796487 @default.
• W2058912845 cites W2124658641 @default.
• W2058912845 cites W2128270335 @default.
• W2058912845 cites W2137258759 @default.
• W2058912845 cites W2252404386 @default.
• W2058912845 cites W2326860105 @default.
• W2058912845 doi "https://doi.org/10.1016/j.placenta.2005.10.006" @default.
• W2058912845 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16368136" @default.
• W2058912845 hasPublicationYear "2006" @default.
• W2058912845 type Work @default.
• W2058912845 sameAs 2058912845 @default.
• W2058912845 citedByCount "20" @default.
• W2058912845 countsByYear W20589128452012 @default.
• W2058912845 countsByYear W20589128452013 @default.
• W2058912845 countsByYear W20589128452014 @default.
• W2058912845 countsByYear W20589128452016 @default.
• W2058912845 countsByYear W20589128452018 @default.
• W2058912845 countsByYear W20589128452019 @default.
• W2058912845 countsByYear W20589128452021 @default.
• W2058912845 countsByYear W20589128452022 @default.
• W2058912845 crossrefType "journal-article" @default.
• W2058912845 hasAuthorship W2058912845A5016527328 @default.
• W2058912845 hasAuthorship W2058912845A5026438725 @default.
• W2058912845 hasAuthorship W2058912845A5083856804 @default.
• W2058912845 hasConcept C120770815 @default.
• W2058912845 hasConcept C126322002 @default.
• W2058912845 hasConcept C134018914 @default.
• W2058912845 hasConcept C172680121 @default.
• W2058912845 hasConcept C178790620 @default.
• W2058912845 hasConcept C185592680 @default.
• W2058912845 hasConcept C18699975 @default.
• W2058912845 hasConcept C2776953305 @default.
• W2058912845 hasConcept C2779066535 @default.
• W2058912845 hasConcept C2779234561 @default.
• W2058912845 hasConcept C2779961880 @default.
• W2058912845 hasConcept C29323129 @default.
• W2058912845 hasConcept C4141045 @default.
• W2058912845 hasConcept C519063684 @default.
• W2058912845 hasConcept C540031477 @default.
• W2058912845 hasConcept C54355233 @default.
• W2058912845 hasConcept C71924100 @default.
• W2058912845 hasConcept C7836513 @default.
• W2058912845 hasConcept C86803240 @default.
• W2058912845 hasConceptScore W2058912845C120770815 @default.
• W2058912845 hasConceptScore W2058912845C126322002 @default.
• W2058912845 hasConceptScore W2058912845C134018914 @default.
• W2058912845 hasConceptScore W2058912845C172680121 @default.
• W2058912845 hasConceptScore W2058912845C178790620 @default.
• W2058912845 hasConceptScore W2058912845C185592680 @default.
• W2058912845 hasConceptScore W2058912845C18699975 @default.
• W2058912845 hasConceptScore W2058912845C2776953305 @default.
• W2058912845 hasConceptScore W2058912845C2779066535 @default.
• W2058912845 hasConceptScore W2058912845C2779234561 @default.
• W2058912845 hasConceptScore W2058912845C2779961880 @default.
• W2058912845 hasConceptScore W2058912845C29323129 @default.
• W2058912845 hasConceptScore W2058912845C4141045 @default.
• W2058912845 hasConceptScore W2058912845C519063684 @default.
• W2058912845 hasConceptScore W2058912845C540031477 @default.
• W2058912845 hasConceptScore W2058912845C54355233 @default.
• W2058912845 hasConceptScore W2058912845C71924100 @default.
• W2058912845 hasConceptScore W2058912845C7836513 @default.
• W2058912845 hasConceptScore W2058912845C86803240 @default.
• W2058912845 hasIssue "9-10" @default.
• W2058912845 hasLocation W20589128451 @default.
• W2058912845 hasLocation W20589128452 @default.
• W2058912845 hasOpenAccess W2058912845 @default.
• W2058912845 hasPrimaryLocation W20589128451 @default.
• W2058912845 hasRelatedWork W142241613 @default.
• W2058912845 hasRelatedWork W1975772580 @default.
• W2058912845 hasRelatedWork W1975823814 @default.
• W2058912845 hasRelatedWork W2001756863 @default.
• W2058912845 hasRelatedWork W2021015175 @default.
• W2058912845 hasRelatedWork W2077247628 @default.
• W2058912845 hasRelatedWork W2085573318 @default.
• W2058912845 hasRelatedWork W2098120608 @default.

• next