FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058932445> ?p ?o ?g. }

• W2058932445 endingPage "306" @default.
• W2058932445 startingPage "297" @default.
• W2058932445 abstract "Postsubarachnoid hemorrhage, systemic inflammatory response syndrome and associated organ system failure are more frequently found in patients in poor neurologic condition. Since subarachnoid hemorrhage causes a profound intrathecal inflammatory response with production of proinflammatory cytokines TNFalpha, IL-1beta, and IL-6, a possible explanation for this association is that brain-derived cytokines may enter the systemic circulation in the presence of postsubarachnoid hemorrhage blood brain barrier disruption to systemically activate inflammatory cascades and thereby contribute to the development of postsubarachnoid hemorrhage systemic inflammatory response syndrome and extracerebral organ system failures. In 44 patients with aneurysmal subarachnoid hemorrhage admitted within 3 days of the initial bleed, extracerebral organ system functions were assessed individually and in aggregate using the modified Multiple Organ Dysfunction Score. Serum and cerebrospinal fluid concentrations of soluble tumor necrosis factor-alpha receptor-I, interleukin-1beta receptor antagonist, and IL-6 were determined during the first 2 weeks after subarachnoid hemorrhage and tested for correlation with (1) admission Hunt-Hess grade, (2) development of systemic inflammatory response syndrome and extracerebral organ system failures, and (3) neurologic outcome. The development of postsubarachnoid hemorrhage systemic inflammatory response syndrome and extracerebral organ system failures was paralleled by a significant increase in serum but not in cerebrospinal fluid levels of soluble tumor necrosis factor-alpha receptor-I and IL-1ra, that is, patients with and without extracerebral organ system failures did not differ in pattern and time course of cerebrospinal fluid cytokine concentrations. In contrast, increasing soluble tumor necrosis factor-alpha receptor-I and interleukin-1beta receptor antagonist serum levels correlated with a higher Multiple Organ Dysfunction score and with individual organ system dysfunctions. Postsubarachnoid hemorrhage, systemic inflammatory response syndrome and extracerebral organ system failures could therefore not be linked to changes in cerebrospinal fluid cytokine concentration profiles." @default.
• W2058932445 created "2016-06-24" @default.
• W2058932445 creator A5006848706 @default.
• W2058932445 creator A5023471727 @default.
• W2058932445 creator A5028793619 @default.
• W2058932445 creator A5033138637 @default.
• W2058932445 creator A5046060796 @default.
• W2058932445 creator A5052722530 @default.
• W2058932445 date "2000-10-01" @default.
• W2058932445 modified "2023-10-17" @default.
• W2058932445 title "Ventricular Cerebrospinal Fluid and Serum Concentrations of sTNFR-I, IL-1ra, and IL-6 After Aneurysmal Subarachnoid Hemorrhage" @default.
• W2058932445 cites W1479683764 @default.
• W2058932445 cites W1496877897 @default.
• W2058932445 cites W1560533789 @default.
• W2058932445 cites W185767050 @default.
• W2058932445 cites W1874700596 @default.
• W2058932445 cites W1963710801 @default.
• W2058932445 cites W1964886080 @default.
• W2058932445 cites W1970120005 @default.
• W2058932445 cites W1973313699 @default.
• W2058932445 cites W1975298116 @default.
• W2058932445 cites W1979327126 @default.
• W2058932445 cites W1980395104 @default.
• W2058932445 cites W1990885249 @default.
• W2058932445 cites W1993537924 @default.
• W2058932445 cites W1997236586 @default.
• W2058932445 cites W2005111715 @default.
• W2058932445 cites W2005475138 @default.
• W2058932445 cites W2007281897 @default.
• W2058932445 cites W2010230586 @default.
• W2058932445 cites W2012066718 @default.
• W2058932445 cites W2015843753 @default.
• W2058932445 cites W2017812906 @default.
• W2058932445 cites W2018366266 @default.
• W2058932445 cites W2022235858 @default.
• W2058932445 cites W2025005044 @default.
• W2058932445 cites W2026353609 @default.
• W2058932445 cites W2026575382 @default.
• W2058932445 cites W2026865446 @default.
• W2058932445 cites W2030801719 @default.
• W2058932445 cites W2033913986 @default.
• W2058932445 cites W2034347690 @default.
• W2058932445 cites W2037516773 @default.
• W2058932445 cites W2037828121 @default.
• W2058932445 cites W2040068581 @default.
• W2058932445 cites W2040957577 @default.
• W2058932445 cites W2047817815 @default.
• W2058932445 cites W2051875651 @default.
• W2058932445 cites W2062260321 @default.
• W2058932445 cites W2062618424 @default.
• W2058932445 cites W2065132110 @default.
• W2058932445 cites W2069132198 @default.
• W2058932445 cites W2074111088 @default.
• W2058932445 cites W2079405518 @default.
• W2058932445 cites W2080171075 @default.
• W2058932445 cites W2082011784 @default.
• W2058932445 cites W2082392681 @default.
• W2058932445 cites W2083074827 @default.
• W2058932445 cites W2085208748 @default.
• W2058932445 cites W2089172549 @default.
• W2058932445 cites W2095290321 @default.
• W2058932445 cites W2111471304 @default.
• W2058932445 cites W2117992648 @default.
• W2058932445 cites W2142585662 @default.
• W2058932445 cites W2150825819 @default.
• W2058932445 cites W2159746265 @default.
• W2058932445 cites W2168925567 @default.
• W2058932445 cites W2321427723 @default.
• W2058932445 cites W2337359323 @default.
• W2058932445 cites W2616555459 @default.
• W2058932445 cites W2729107688 @default.
• W2058932445 cites W2768146862 @default.
• W2058932445 cites W288942681 @default.
• W2058932445 doi "https://doi.org/10.1097/00008506-200010000-00001" @default.
• W2058932445 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11147377" @default.
• W2058932445 hasPublicationYear "2000" @default.
• W2058932445 type Work @default.
• W2058932445 sameAs 2058932445 @default.
• W2058932445 citedByCount "57" @default.
• W2058932445 countsByYear W20589324452012 @default.
• W2058932445 countsByYear W20589324452013 @default.
• W2058932445 countsByYear W20589324452014 @default.
• W2058932445 countsByYear W20589324452015 @default.
• W2058932445 countsByYear W20589324452016 @default.
• W2058932445 countsByYear W20589324452017 @default.
• W2058932445 countsByYear W20589324452018 @default.
• W2058932445 countsByYear W20589324452019 @default.
• W2058932445 countsByYear W20589324452020 @default.
• W2058932445 countsByYear W20589324452021 @default.
• W2058932445 countsByYear W20589324452022 @default.
• W2058932445 countsByYear W20589324452023 @default.
• W2058932445 crossrefType "journal-article" @default.
• W2058932445 hasAuthorship W2058932445A5006848706 @default.
• W2058932445 hasAuthorship W2058932445A5023471727 @default.
• W2058932445 hasAuthorship W2058932445A5028793619 @default.
• W2058932445 hasAuthorship W2058932445A5033138637 @default.
• W2058932445 hasAuthorship W2058932445A5046060796 @default.
• W2058932445 hasAuthorship W2058932445A5052722530 @default.

• next