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- W2058938497 abstract "The literature concerning the effects of the adrenal steroids cortisone and hydrocortisone on tissues and systems is exhaustive. Hydrocortisone U. S. P. (17-hydroxycorticosterone; Compound F) has been reported to be more potent, milligram by milligram, than cortisone,1and the main physiologic actions of the two are similar.2Hydrocortisone used in local application allows a higher concentration of the hormone in the tissue, and the difference in local effectiveness as compared with that of cortisone remains unexplained.3 Wound healing is delayed by cortisone,* and several tissues have been reported to be affected in the healing process when the adrenocortical steroid is given in high doses parenterally,7by local application, by subcutaneous injection,8or subconjunctivally.† The action of cortisone in the healing of the central nervous system as noted experimentally has been observed to be a depression of the early inflammatory phase in puncture wounds of the" @default.
- W2058938497 created "2016-06-24" @default.
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- W2058938497 date "1955-10-01" @default.
- W2058938497 modified "2023-09-27" @default.
- W2058938497 title "The Effect of Hydrocortisone on the Healing of Wounds of the Brain" @default.
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- W2058938497 doi "https://doi.org/10.1001/archneurpsyc.1955.02330160057008" @default.
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