FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058945414> ?p ?o ?g. }

• W2058945414 endingPage "119" @default.
• W2058945414 startingPage "110" @default.
• W2058945414 abstract "Elimination of eighth-nerve activity results in the death of 30% of the neurons in the chick cochlear nucleus, nucleus magnocellularis (NM). One early event in this cell death cascade is the disruption of ribosomes in NM neurons which can be observed within 1 h following deafferentation. These rapid changes in ribosomes can be visualized using Y10B, a monoclonal antibody that recognizes ribosomal RNA. Previous studies using a brain slice preparation of the avian brain stem auditory system have shown that activation of metabotropic glutamate receptors (mGluRs) is necessary for the activity-dependent maintenance of Y10B antigenicity. The purpose of the present study was to determine if group I and/or II mGluRs are necessary for this activity-dependent regulation. This was accomplished by selectively blocking group I or II receptors while unilaterally stimulating the auditory nerve in vitro. In normal media, unilateral stimulation of the auditory nerve resulted in darker Y10B immunolabeling of NM neurons on the stimulated side of the slice. The group I antagonist (RS)-1-aminoindan-1,5-dicarboxylic acid (AIDA) and the group II antagonists LY341495 and (S)-α-ethylglutamic acid (EGLU) all prevented the activity-dependent difference in Y10B immunolabeling. These data suggest that both group I and II mGluRs play vital roles in the activity-dependent regulation of ribosomes in NM." @default.
• W2058945414 created "2016-06-24" @default.
• W2058945414 creator A5053034986 @default.
• W2058945414 creator A5057473840 @default.
• W2058945414 date "2004-07-01" @default.
• W2058945414 modified "2023-09-26" @default.
• W2058945414 title "Group I and II metabotropic glutamate receptors are necessary for the activity-dependent regulation of ribosomes in chick auditory neurons" @default.
• W2058945414 cites W1538992523 @default.
• W2058945414 cites W1578289135 @default.
• W2058945414 cites W1753891391 @default.
• W2058945414 cites W1858747637 @default.
• W2058945414 cites W1949802683 @default.
• W2058945414 cites W1963945234 @default.
• W2058945414 cites W1968568568 @default.
• W2058945414 cites W1971656169 @default.
• W2058945414 cites W1977696150 @default.
• W2058945414 cites W1991444172 @default.
• W2058945414 cites W1991686031 @default.
• W2058945414 cites W1995793875 @default.
• W2058945414 cites W1997924422 @default.
• W2058945414 cites W2002574600 @default.
• W2058945414 cites W2009027181 @default.
• W2058945414 cites W2010291532 @default.
• W2058945414 cites W2029542833 @default.
• W2058945414 cites W2031315226 @default.
• W2058945414 cites W2033487651 @default.
• W2058945414 cites W2036327283 @default.
• W2058945414 cites W2040023740 @default.
• W2058945414 cites W2046301993 @default.
• W2058945414 cites W2055391764 @default.
• W2058945414 cites W2056207010 @default.
• W2058945414 cites W2058088811 @default.
• W2058945414 cites W2060728682 @default.
• W2058945414 cites W2063478982 @default.
• W2058945414 cites W2070547201 @default.
• W2058945414 cites W2071847665 @default.
• W2058945414 cites W2073732519 @default.
• W2058945414 cites W2078199061 @default.
• W2058945414 cites W2078885383 @default.
• W2058945414 cites W2080529726 @default.
• W2058945414 cites W2081831423 @default.
• W2058945414 cites W2085984787 @default.
• W2058945414 cites W2093341222 @default.
• W2058945414 cites W2093605386 @default.
• W2058945414 cites W2106042714 @default.
• W2058945414 cites W2106560349 @default.
• W2058945414 cites W2108946626 @default.
• W2058945414 cites W2120272723 @default.
• W2058945414 cites W2122358271 @default.
• W2058945414 cites W2128556377 @default.
• W2058945414 cites W2135662935 @default.
• W2058945414 cites W2153450997 @default.
• W2058945414 cites W2169548388 @default.
• W2058945414 cites W2170413042 @default.
• W2058945414 cites W2230464288 @default.
• W2058945414 cites W2341695286 @default.
• W2058945414 cites W2405592948 @default.
• W2058945414 cites W2409766273 @default.
• W2058945414 cites W4248835773 @default.
• W2058945414 cites W4300258638 @default.
• W2058945414 doi "https://doi.org/10.1016/j.brainres.2004.03.066" @default.
• W2058945414 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15212997" @default.
• W2058945414 hasPublicationYear "2004" @default.
• W2058945414 type Work @default.
• W2058945414 sameAs 2058945414 @default.
• W2058945414 citedByCount "15" @default.
• W2058945414 countsByYear W20589454142014 @default.
• W2058945414 countsByYear W20589454142016 @default.
• W2058945414 countsByYear W20589454142017 @default.
• W2058945414 countsByYear W20589454142018 @default.
• W2058945414 countsByYear W20589454142019 @default.
• W2058945414 crossrefType "journal-article" @default.
• W2058945414 hasAuthorship W2058945414A5053034986 @default.
• W2058945414 hasAuthorship W2058945414A5057473840 @default.
• W2058945414 hasConcept C104317684 @default.
• W2058945414 hasConcept C169760540 @default.
• W2058945414 hasConcept C170493617 @default.
• W2058945414 hasConcept C203014093 @default.
• W2058945414 hasConcept C204232928 @default.
• W2058945414 hasConcept C26702167 @default.
• W2058945414 hasConcept C2777662796 @default.
• W2058945414 hasConcept C2777877921 @default.
• W2058945414 hasConcept C2780723820 @default.
• W2058945414 hasConcept C49051014 @default.
• W2058945414 hasConcept C55493867 @default.
• W2058945414 hasConcept C61174792 @default.
• W2058945414 hasConcept C67018056 @default.
• W2058945414 hasConcept C67705224 @default.
• W2058945414 hasConcept C86803240 @default.
• W2058945414 hasConcept C88478588 @default.
• W2058945414 hasConcept C95444343 @default.
• W2058945414 hasConceptScore W2058945414C104317684 @default.
• W2058945414 hasConceptScore W2058945414C169760540 @default.
• W2058945414 hasConceptScore W2058945414C170493617 @default.
• W2058945414 hasConceptScore W2058945414C203014093 @default.
• W2058945414 hasConceptScore W2058945414C204232928 @default.
• W2058945414 hasConceptScore W2058945414C26702167 @default.
• W2058945414 hasConceptScore W2058945414C2777662796 @default.

• next