FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2058953048> ?p ?o ?g. }

• W2058953048 endingPage "e63737" @default.
• W2058953048 startingPage "e63737" @default.
• W2058953048 abstract "Replication and assembly of vertebrate reoviruses occur in specific intracellular compartments known as viral factories. Recently, NS88 and NS80, the nonstructural proteins from aquareoviruses, have been proposed to share common traits with µNS from orthoreoviruses, which are involved in the formation of viral factories.In this study, the NS80 characteristics and its interactions with other viral components were investigated. We observed that the NS80 structure ensured its self-aggregation and selective recruitment of viral proteins to viral factories like structures (VFLS). The minimum amino acids (aa) of NS80 required for VFLS formation included 193 aa at the C-terminal. However, this truncated protein only contained one aa coil and located in the nucleus. Its N-terminal residual regions, aa 1-55 and aa 55-85, were required for recruiting viral nonstructural protein NS38 and structural protein VP3, respectively. A conserved N-terminal region of NS38, which was responsible for the interaction with NS80, was also identified. Moreover, the minimal region of C-terminal residues, aa 506-742 (Δ505), required for NS80 self-aggregation in the cytoplasm, and aa 550-742 (Δ549), which are sufficient for recruiting viral structure proteins VP1, VP2, and VP4 were also identified.The present study shows detailed interactions between NS80 and NS38 or other viral proteins. Sequence and structure characteristics of NS80 ensures its self-aggregation to form VFLS (either in the cytoplasm or nucleus) and recruitment of viral structural or nonstructural proteins." @default.
• W2058953048 created "2016-06-24" @default.
• W2058953048 creator A5020741182 @default.
• W2058953048 creator A5037331367 @default.
• W2058953048 creator A5054703619 @default.
• W2058953048 date "2013-05-06" @default.
• W2058953048 modified "2023-10-12" @default.
• W2058953048 title "Nonstructural Protein NS80 Is Crucial in Recruiting Viral Components to Form Aquareoviral Factories" @default.
• W2058953048 cites W1546570611 @default.
• W2058953048 cites W1966455695 @default.
• W2058953048 cites W1969275631 @default.
• W2058953048 cites W1979667801 @default.
• W2058953048 cites W1980929865 @default.
• W2058953048 cites W1985178009 @default.
• W2058953048 cites W1985647599 @default.
• W2058953048 cites W1990580642 @default.
• W2058953048 cites W1996550262 @default.
• W2058953048 cites W1997016500 @default.
• W2058953048 cites W2014407475 @default.
• W2058953048 cites W2015626866 @default.
• W2058953048 cites W2015761674 @default.
• W2058953048 cites W2017909807 @default.
• W2058953048 cites W2022846740 @default.
• W2058953048 cites W2024291419 @default.
• W2058953048 cites W2024645073 @default.
• W2058953048 cites W2029361316 @default.
• W2058953048 cites W2033709999 @default.
• W2058953048 cites W2039406849 @default.
• W2058953048 cites W2047946045 @default.
• W2058953048 cites W2053948071 @default.
• W2058953048 cites W2058427686 @default.
• W2058953048 cites W2060552385 @default.
• W2058953048 cites W2061803196 @default.
• W2058953048 cites W2066824126 @default.
• W2058953048 cites W2068668717 @default.
• W2058953048 cites W2081126760 @default.
• W2058953048 cites W2085898315 @default.
• W2058953048 cites W2086155795 @default.
• W2058953048 cites W2090665703 @default.
• W2058953048 cites W2095035720 @default.
• W2058953048 cites W2095549733 @default.
• W2058953048 cites W2096775204 @default.
• W2058953048 cites W2097453900 @default.
• W2058953048 cites W2100686141 @default.
• W2058953048 cites W2117756276 @default.
• W2058953048 cites W2134255786 @default.
• W2058953048 cites W2137859768 @default.
• W2058953048 cites W2139855364 @default.
• W2058953048 cites W2143216839 @default.
• W2058953048 cites W2144430874 @default.
• W2058953048 cites W2145386287 @default.
• W2058953048 cites W2156163564 @default.
• W2058953048 cites W2158714788 @default.
• W2058953048 cites W2158797336 @default.
• W2058953048 cites W2159220562 @default.
• W2058953048 cites W2160066656 @default.
• W2058953048 cites W2160418516 @default.
• W2058953048 cites W2167171684 @default.
• W2058953048 cites W2171566201 @default.
• W2058953048 doi "https://doi.org/10.1371/journal.pone.0063737" @default.
• W2058953048 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3646018" @default.
• W2058953048 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23671697" @default.
• W2058953048 hasPublicationYear "2013" @default.
• W2058953048 type Work @default.
• W2058953048 sameAs 2058953048 @default.
• W2058953048 citedByCount "20" @default.
• W2058953048 countsByYear W20589530482013 @default.
• W2058953048 countsByYear W20589530482014 @default.
• W2058953048 countsByYear W20589530482015 @default.
• W2058953048 countsByYear W20589530482016 @default.
• W2058953048 countsByYear W20589530482018 @default.
• W2058953048 countsByYear W20589530482019 @default.
• W2058953048 countsByYear W20589530482021 @default.
• W2058953048 countsByYear W20589530482022 @default.
• W2058953048 countsByYear W20589530482023 @default.
• W2058953048 crossrefType "journal-article" @default.
• W2058953048 hasAuthorship W2058953048A5020741182 @default.
• W2058953048 hasAuthorship W2058953048A5037331367 @default.
• W2058953048 hasAuthorship W2058953048A5054703619 @default.
• W2058953048 hasBestOaLocation W20589530481 @default.
• W2058953048 hasConcept C104317684 @default.
• W2058953048 hasConcept C10852380 @default.
• W2058953048 hasConcept C140704245 @default.
• W2058953048 hasConcept C159047783 @default.
• W2058953048 hasConcept C167625842 @default.
• W2058953048 hasConcept C190062978 @default.
• W2058953048 hasConcept C2522874641 @default.
• W2058953048 hasConcept C2780879997 @default.
• W2058953048 hasConcept C47701112 @default.
• W2058953048 hasConcept C515207424 @default.
• W2058953048 hasConcept C55493867 @default.
• W2058953048 hasConcept C58475186 @default.
• W2058953048 hasConcept C86803240 @default.
• W2058953048 hasConcept C95444343 @default.
• W2058953048 hasConceptScore W2058953048C104317684 @default.
• W2058953048 hasConceptScore W2058953048C10852380 @default.
• W2058953048 hasConceptScore W2058953048C140704245 @default.
• W2058953048 hasConceptScore W2058953048C159047783 @default.

• next