FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059042932> ?p ?o ?g. }

• W2059042932 endingPage "437" @default.
• W2059042932 startingPage "424" @default.
• W2059042932 abstract "The time-dependent accumulation of phosphatidyldimethylethanolamine in formaldehyde-induced vesicles obtained from a somatic cell hybrid line was investigated. From a number of considerations including a two-fold enrichment of cholesterol and sphingomyelin it was concluded that these vesicles were derived from the cell plasma membrane. A progressive depletion of phosphatidylcholine, the major vesicle phospholipid, was observed in cells supplemented for various time periods with dimethylethanolamine. This depletion was accompanied by a concomitant increase in the amount of lipid analog. The time-dependent alteration of the phospholipid polar head group in intact cells was almost identical to that observed in isolated plasma membrane vesicles, suggesting a rapid equilibration of the de novo synthesized phospholipid with the cell surface compartment. From the initial velocity rate, the time required for the phosphatidylcholine pool to double was about 12 h. Agarose-linked phospholipase A2 was used to measure the relative composition of choline- and dimethylethanolamine-phosphoglycerides in the outer surface of vesicles prepared from cells with different degrees of polar head group substitution. The gradual appearance of lysodimethylethanolamine lipid analog in vesicles treated with phospholipase A2 suggested an asymmetric distribution of the phospholipid between the interior and the exterior part of the vesicle. This asymmetry was maximal up to about 4 h following the addition of dimethylethanolamine to the culture medium and was of a transient nature as the lipid analog accumulated on both sides of the plasma membrane. Based on these measurements a fast followed by a slow translocation component could be distinguished with apparent doubling times of 7 and 43 h for the lipid analog, respectively. As the analog becomes the predominant cellular phospholipid a significant increase in the vesicle lipid fluidity was measured." @default.
• W2059042932 created "2016-06-24" @default.
• W2059042932 creator A5017829582 @default.
• W2059042932 creator A5050042035 @default.
• W2059042932 date "1979-06-01" @default.
• W2059042932 modified "2023-09-23" @default.
• W2059042932 title "Translocation and turnover of phospholipid analogs in plasma membrane-derived vesicles from cell cultures" @default.
• W2059042932 cites W1495082944 @default.
• W2059042932 cites W1513897103 @default.
• W2059042932 cites W1524844977 @default.
• W2059042932 cites W1526385127 @default.
• W2059042932 cites W1549802820 @default.
• W2059042932 cites W1604827595 @default.
• W2059042932 cites W1604863183 @default.
• W2059042932 cites W1775749144 @default.
• W2059042932 cites W184029216 @default.
• W2059042932 cites W1966319739 @default.
• W2059042932 cites W1968733854 @default.
• W2059042932 cites W1974013623 @default.
• W2059042932 cites W1986752665 @default.
• W2059042932 cites W1993185807 @default.
• W2059042932 cites W2009484394 @default.
• W2059042932 cites W2015879325 @default.
• W2059042932 cites W2020220074 @default.
• W2059042932 cites W2032319355 @default.
• W2059042932 cites W2033222222 @default.
• W2059042932 cites W2034791231 @default.
• W2059042932 cites W2039492150 @default.
• W2059042932 cites W2050635132 @default.
• W2059042932 cites W2080648322 @default.
• W2059042932 cites W2087379708 @default.
• W2059042932 cites W2089433759 @default.
• W2059042932 cites W2093861837 @default.
• W2059042932 cites W2129745051 @default.
• W2059042932 cites W3209951468 @default.
• W2059042932 doi "https://doi.org/10.1016/0005-2736(79)90298-0" @default.
• W2059042932 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/454594" @default.
• W2059042932 hasPublicationYear "1979" @default.
• W2059042932 type Work @default.
• W2059042932 sameAs 2059042932 @default.
• W2059042932 citedByCount "18" @default.
• W2059042932 countsByYear W20590429322014 @default.
• W2059042932 countsByYear W20590429322016 @default.
• W2059042932 crossrefType "journal-article" @default.
• W2059042932 hasAuthorship W2059042932A5017829582 @default.
• W2059042932 hasAuthorship W2059042932A5050042035 @default.
• W2059042932 hasConcept C12554922 @default.
• W2059042932 hasConcept C130316041 @default.
• W2059042932 hasConcept C181199279 @default.
• W2059042932 hasConcept C185592680 @default.
• W2059042932 hasConcept C2776330855 @default.
• W2059042932 hasConcept C2776551241 @default.
• W2059042932 hasConcept C2778106830 @default.
• W2059042932 hasConcept C2778918659 @default.
• W2059042932 hasConcept C2779564620 @default.
• W2059042932 hasConcept C41625074 @default.
• W2059042932 hasConcept C55493867 @default.
• W2059042932 hasConcept C61322309 @default.
• W2059042932 hasConcept C86803240 @default.
• W2059042932 hasConceptScore W2059042932C12554922 @default.
• W2059042932 hasConceptScore W2059042932C130316041 @default.
• W2059042932 hasConceptScore W2059042932C181199279 @default.
• W2059042932 hasConceptScore W2059042932C185592680 @default.
• W2059042932 hasConceptScore W2059042932C2776330855 @default.
• W2059042932 hasConceptScore W2059042932C2776551241 @default.
• W2059042932 hasConceptScore W2059042932C2778106830 @default.
• W2059042932 hasConceptScore W2059042932C2778918659 @default.
• W2059042932 hasConceptScore W2059042932C2779564620 @default.
• W2059042932 hasConceptScore W2059042932C41625074 @default.
• W2059042932 hasConceptScore W2059042932C55493867 @default.
• W2059042932 hasConceptScore W2059042932C61322309 @default.
• W2059042932 hasConceptScore W2059042932C86803240 @default.
• W2059042932 hasIssue "3" @default.
• W2059042932 hasLocation W20590429321 @default.
• W2059042932 hasLocation W20590429322 @default.
• W2059042932 hasOpenAccess W2059042932 @default.
• W2059042932 hasPrimaryLocation W20590429321 @default.
• W2059042932 hasRelatedWork W1969934290 @default.
• W2059042932 hasRelatedWork W1978061327 @default.
• W2059042932 hasRelatedWork W2000266304 @default.
• W2059042932 hasRelatedWork W2004975012 @default.
• W2059042932 hasRelatedWork W2015315907 @default.
• W2059042932 hasRelatedWork W2059042932 @default.
• W2059042932 hasRelatedWork W2072843686 @default.
• W2059042932 hasRelatedWork W2410967278 @default.
• W2059042932 hasRelatedWork W2472937173 @default.
• W2059042932 hasRelatedWork W77534462 @default.
• W2059042932 hasVolume "553" @default.
• W2059042932 isParatext "false" @default.
• W2059042932 isRetracted "false" @default.
• W2059042932 magId "2059042932" @default.
• W2059042932 workType "article" @default.