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- W2059043608 abstract "Abstract The mechanism and site of action of the hypertensive response to Brazilian scorpion venom extract were studied in cats and dogs anaesthetized with sodium pentobarbitone. The results are consistent with an indirect action of the venom through the release of catecholamines. Even though the site of action of the venom is the sympathetic post-ganglionic fiber, its intimate mechanism seems to be different from that of tyramine since the hypertensive response is not restored in reserpinized animals infused with noradrenaline. The hypertensive effect is blocked by guanethidine, indicating the granular depots as the site of action of the venom. It has also been observed that the venom potentiates the hypertensive response to injected catecholamines and to carotid artery occlusion, suggesting participation of the venom in the mechanism of inactivation of catecholamines." @default.
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- W2059043608 date "1974-03-01" @default.
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- W2059043608 title "The mechanism of the hypertensive effect of brazilian scorpion venom (Tityus serrulatus lutz e mello)" @default.
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- W2059043608 doi "https://doi.org/10.1016/0041-0101(74)90238-4" @default.
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