FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059090034> ?p ?o ?g. }

• W2059090034 endingPage "53" @default.
• W2059090034 startingPage "53" @default.
• W2059090034 abstract "PURPOSE: To examine predictors of the leg hemodynamic response to exercise in middle-aged men and women. METHODS: We measured femoral artery blood flow (FBF; from Doppler-ultrasound derived measurements of diameter and blood velocity), mean arterial pressure (MAP), and femoral vascular conductance (FVC; calculated as the quotient of FBF and MAP) at rest and during five minutes of steady-state single knee-extensor exercise at an ∼ 10 watt (W) workload in healthy men (n=23) and women (n=30) (ages 40-72). Exercising FBF and FVC were normalized to power output achieved during exercise (FBF/W and FVC/W, respectively). Age, maximal quadriceps isometric and isokinetic strength (isokinetic dynamometer), maximal oxygen uptake (VO2max; graded treadmill test to maximal exertion), estimated physical activity (scores from the Paffenbarger Physical Activity Questionnaire), blood pressure, and anthropometric variables (estimated quadriceps muscle mass and body mass index (BMI)) were investigated with stepwise multiple linear regression as predictors of FBF/W and FVC/W in men and women separately. RESULTS: The effect of age on FBF/W and FVC/W was negative and marginally significant in men (p = 0.06 and 0.09, respectively) but highly insignificant in women (p = 0.91 and 0.89, respectively). Exercising FBF/W was predicted by age, BMI, and resting femoral blood flow (p < 0.01) and exercising FVC/W was predicted by age, BMI and resting femoral vascular conductance (p < 0.01) in men. Conversely, both exercising FBF/W and FVC/W were predicted by resting systolic blood pressure and weekly physical activity (Paffenbarger question 6 score) (p < 0.01 and p = 0.01, respectively) in women. CONCLUSIONS: There is sex-specificity in factors mediating exercising leg blood flow and vascular conductance in middle-aged adults. Notably, there is no relation between age and submaximal leg exercise hemodynamics in women across this age range, suggesting that the significant deficits in exercising leg vasodilator responses previously observed in older women may either occur prior to middle-age or be mediated by factors other than chronological age. Research Supported by NIH award 5R01HL081893-03." @default.
• W2059090034 created "2016-06-24" @default.
• W2059090034 creator A5003283875 @default.
• W2059090034 creator A5041482139 @default.
• W2059090034 creator A5059170891 @default.
• W2059090034 creator A5063265113 @default.
• W2059090034 creator A5089562752 @default.
• W2059090034 date "2010-05-01" @default.
• W2059090034 modified "2023-09-26" @default.
• W2059090034 title "Sex-specific Effect Of Age On Submaximal Leg Exercise Hemodynamics In Middle-aged Adults" @default.
• W2059090034 doi "https://doi.org/10.1249/01.mss.0000385177.06109.0c" @default.
• W2059090034 hasPublicationYear "2010" @default.
• W2059090034 type Work @default.
• W2059090034 sameAs 2059090034 @default.
• W2059090034 citedByCount "0" @default.
• W2059090034 crossrefType "journal-article" @default.
• W2059090034 hasAuthorship W2059090034A5003283875 @default.
• W2059090034 hasAuthorship W2059090034A5041482139 @default.
• W2059090034 hasAuthorship W2059090034A5059170891 @default.
• W2059090034 hasAuthorship W2059090034A5063265113 @default.
• W2059090034 hasAuthorship W2059090034A5089562752 @default.
• W2059090034 hasBestOaLocation W20590900341 @default.
• W2059090034 hasConcept C103486182 @default.
• W2059090034 hasConcept C126322002 @default.
• W2059090034 hasConcept C164705383 @default.
• W2059090034 hasConcept C178853913 @default.
• W2059090034 hasConcept C1862650 @default.
• W2059090034 hasConcept C196310339 @default.
• W2059090034 hasConcept C2777953023 @default.
• W2059090034 hasConcept C2780221984 @default.
• W2059090034 hasConcept C61427482 @default.
• W2059090034 hasConcept C71924100 @default.
• W2059090034 hasConcept C84393581 @default.
• W2059090034 hasConceptScore W2059090034C103486182 @default.
• W2059090034 hasConceptScore W2059090034C126322002 @default.
• W2059090034 hasConceptScore W2059090034C164705383 @default.
• W2059090034 hasConceptScore W2059090034C178853913 @default.
• W2059090034 hasConceptScore W2059090034C1862650 @default.
• W2059090034 hasConceptScore W2059090034C196310339 @default.
• W2059090034 hasConceptScore W2059090034C2777953023 @default.
• W2059090034 hasConceptScore W2059090034C2780221984 @default.
• W2059090034 hasConceptScore W2059090034C61427482 @default.
• W2059090034 hasConceptScore W2059090034C71924100 @default.
• W2059090034 hasConceptScore W2059090034C84393581 @default.
• W2059090034 hasIssue "5" @default.
• W2059090034 hasLocation W20590900341 @default.
• W2059090034 hasLocation W20590900342 @default.
• W2059090034 hasOpenAccess W2059090034 @default.
• W2059090034 hasPrimaryLocation W20590900341 @default.
• W2059090034 hasRelatedWork W1827247497 @default.
• W2059090034 hasRelatedWork W1931080894 @default.
• W2059090034 hasRelatedWork W2047402867 @default.
• W2059090034 hasRelatedWork W2061114995 @default.
• W2059090034 hasRelatedWork W2063826327 @default.
• W2059090034 hasRelatedWork W2168539652 @default.
• W2059090034 hasRelatedWork W2355237307 @default.
• W2059090034 hasRelatedWork W2557376994 @default.
• W2059090034 hasRelatedWork W2946871987 @default.
• W2059090034 hasRelatedWork W3127060192 @default.
• W2059090034 hasVolume "42" @default.
• W2059090034 isParatext "false" @default.
• W2059090034 isRetracted "false" @default.
• W2059090034 magId "2059090034" @default.
• W2059090034 workType "article" @default.