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- W2059093778 abstract "Predictive genetic testing is currently used mainly for untreatable conditions, such as Huntington's disease, or prenatal detection of serious genetic disorders such as cystic fibrosis. Prenatal tests are usually accompanied by an offer of termination of affected pregnancies. Genes have now been isolated that are associated with potentially preventable diseases such as heart disease and cancer and with increased risk from smoking and obesity. This has raised the possibility of providing predictive information to many more people. Such information may eventually reduce disease by facilitating the development of better targeted and more effective treatment.Informing people of their genetic susceptibility to disease may motivate them to change their behaviour to reduce their risks. However, changing behaviour is often difficult. In this article we review the limited evidence concerning behavioural responses to genetic information on risk. We use this and the literature on behavioural change to consider if and how behaviour might be changed in response to genetic information.#### Summary pointsChanging behaviour is difficultBehavioural change is most likely in motivated people who participate in effective interventionsProviding people with genetic information on risk may not increase their motivation to change behaviour and in some cases may decrease motivationBehavioural change may be more likely if people are persuaded that changing their behaviour can reduce the risk of an adverse health outcome and they are given access to evidence based interventionsFurther research is needed to evaluate programmes in which genetic risk information is given, including evaluation of different ways of giving informationEffective interventions to change behaviour after provision of information on risk need to be developedWe searched Medline, PsycINFO, and the Social Science Citation Index using the following terms: health behavior; illness behavior; genetic screening or mass screening; cancer screening, health screening, mammography, or preventive medicine; genetic counselling, genetic …" @default.
- W2059093778 created "2016-06-24" @default.
- W2059093778 creator A5051207808 @default.
- W2059093778 date "2001-04-28" @default.
- W2059093778 modified "2023-10-16" @default.
- W2059093778 title "Genetic risk and behavioural change" @default.
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- W2059093778 doi "https://doi.org/10.1136/bmj.322.7293.1056" @default.
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