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• W2059094743 abstract "The 5-HT(7) receptor is a more recently discovered G-protein-coupled receptor for serotonin. The functions and possible clinical relevance of this receptor are not yet fully understood. The present paper reviews to what extent the use of animal models of learning and memory and other techniques have implicated the 5-HT(7) receptor in such processes. The studies have used a combination of pharmacological and genetic tools targeting the receptor to evaluate effects on behavior and cellular mechanisms. In tests such as the Barnes maze, contextual fear conditioning and novel location recognition that involve spatial learning and memory there is a considerable amount of evidence supporting an involvement of the 5-HT(7) receptor. Supporting evidence has also been obtained in studies of mRNA expression and cellular signaling as well as in electrophysiological experiments. Especially interesting are the subtle but distinct effects observed in hippocampus-dependent models of place learning where impairments have been described in mice lacking the 5-HT(7) receptor or after administration of a selective antagonist. While more work is required, it appears that 5-HT(7) receptors are particularly important in allocentric representation processes. In instrumental learning tasks both procognitive effects and impairments in memory have been observed using pharmacological tools targeting the 5-HT(7) receptor. In conclusion, the use of pharmacological and genetic tools in animal studies of learning and memory suggest a potentially important role for the 5-HT(7) receptor in cognitive processes." @default.
• W2059094743 created "2016-06-24" @default.
• W2059094743 creator A5064679989 @default.
• W2059094743 creator A5081128904 @default.
• W2059094743 date "2011-04-11" @default.
• W2059094743 modified "2023-10-10" @default.
• W2059094743 title "The 5-HT7 receptor in learning and memory" @default.
• W2059094743 cites W1479747866 @default.
• W2059094743 cites W1494265839 @default.
• W2059094743 cites W1524125780 @default.
• W2059094743 cites W1565257873 @default.
• W2059094743 cites W1818981862 @default.
• W2059094743 cites W1966384693 @default.
• W2059094743 cites W1966819687 @default.
• W2059094743 cites W1970281475 @default.
• W2059094743 cites W1970852151 @default.
• W2059094743 cites W1975950121 @default.
• W2059094743 cites W1976978180 @default.
• W2059094743 cites W1980024704 @default.
• W2059094743 cites W1982008289 @default.
• W2059094743 cites W1982173448 @default.
• W2059094743 cites W1989106367 @default.
• W2059094743 cites W1989163181 @default.
• W2059094743 cites W1993236628 @default.
• W2059094743 cites W1994260522 @default.
• W2059094743 cites W2002287707 @default.
• W2059094743 cites W2002337966 @default.
• W2059094743 cites W2005762757 @default.
• W2059094743 cites W2006618461 @default.
• W2059094743 cites W2007185003 @default.
• W2059094743 cites W2008374290 @default.
• W2059094743 cites W2009710897 @default.
• W2059094743 cites W2013903154 @default.
• W2059094743 cites W2014001501 @default.
• W2059094743 cites W2019322821 @default.
• W2059094743 cites W2021374111 @default.
• W2059094743 cites W2022224180 @default.
• W2059094743 cites W2024179362 @default.
• W2059094743 cites W2028336702 @default.
• W2059094743 cites W2029167119 @default.
• W2059094743 cites W2031914919 @default.
• W2059094743 cites W2033848049 @default.
• W2059094743 cites W2035261621 @default.
• W2059094743 cites W2037491021 @default.
• W2059094743 cites W2038220499 @default.
• W2059094743 cites W2040903359 @default.
• W2059094743 cites W2042535216 @default.
• W2059094743 cites W2046298256 @default.
• W2059094743 cites W2048868418 @default.
• W2059094743 cites W2053127867 @default.
• W2059094743 cites W2057175067 @default.
• W2059094743 cites W2058356149 @default.
• W2059094743 cites W2059057526 @default.
• W2059094743 cites W2059126452 @default.
• W2059094743 cites W2059215368 @default.
• W2059094743 cites W2059612248 @default.
• W2059094743 cites W2064669765 @default.
• W2059094743 cites W2066701183 @default.
• W2059094743 cites W2068556157 @default.
• W2059094743 cites W2070757004 @default.
• W2059094743 cites W2072438443 @default.
• W2059094743 cites W2075675414 @default.
• W2059094743 cites W2080461836 @default.
• W2059094743 cites W2085977381 @default.
• W2059094743 cites W2088183396 @default.
• W2059094743 cites W2093431980 @default.
• W2059094743 cites W2094301775 @default.
• W2059094743 cites W2094304925 @default.
• W2059094743 cites W2094391965 @default.
• W2059094743 cites W2094573117 @default.
• W2059094743 cites W2095256251 @default.
• W2059094743 cites W2095286849 @default.
• W2059094743 cites W2095468181 @default.
• W2059094743 cites W2096518324 @default.
• W2059094743 cites W2101753940 @default.
• W2059094743 cites W2102438497 @default.
• W2059094743 cites W2103713548 @default.
• W2059094743 cites W2103861118 @default.
• W2059094743 cites W2106719090 @default.
• W2059094743 cites W2120708919 @default.
• W2059094743 cites W2131553858 @default.
• W2059094743 cites W2133083344 @default.
• W2059094743 cites W2143696278 @default.
• W2059094743 cites W2143787546 @default.
• W2059094743 cites W2143946826 @default.
• W2059094743 cites W2148975835 @default.
• W2059094743 cites W2156544956 @default.
• W2059094743 cites W2157045608 @default.
• W2059094743 cites W2171264145 @default.
• W2059094743 cites W2407597967 @default.
• W2059094743 cites W4232755968 @default.
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• W2059094743 doi "https://doi.org/10.1002/hipo.20938" @default.
• W2059094743 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3310936" @default.
• W2059094743 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21484935" @default.
• W2059094743 hasPublicationYear "2011" @default.
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