Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059122751> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2059122751 endingPage "276" @default.
- W2059122751 startingPage "271" @default.
- W2059122751 abstract "Pneumonia is the reported cause of death of a high proportion of Alzheimer's disease (AD) patients.This study assessed swallowing function to explore the potential risk factors of aspiration pneumonia in AD patients.Data were gathered on 121 AD patients (mean age 78.2, SD 7.5, male/female ratio = 48/73) treated in two psychiatric hospitals. Multiple logistic regression analysis was used to estimate odds ratios for the risk of aspiration pneumonia. The following risk factors were considered: age, severity of dementia, silent brain infarction (SBI) in the basel ganglia, use of psychotropic drugs (neuroleptics and benzodiazepines), and gender. The latency time of the swallowing reflex was analyzed (1) among groups based on the severity of dementia; (2) between groups with and without SBI in the basal ganglia; (3) before and after the use of psychotropic drugs in the group without SBI in the basal ganglia, and (4) between males and females.Aspiration pneumonia in ambulatory AD patients was significantly and independently associated with severe dementia, presence of SBI in the basal ganglia, intake of neuroleptics, and the male gender. The mean latency of the swallowing reflex in the severe AD group was significantly longer compared to that in the mild-to-moderate AD group. The mean latency of the swallowing reflex after the intake of neuroleptics was significantly prolonged compared to that obtained before any neuroleptic intake, whereas there was no significant difference in the mean latency of the swallowing reflex before and after benzodiazepine intake.We recommend the use of the smallest efficacious dosage of neuroleptics especially in treating severely demented AD patients with basal-ganglia infarction. As soon as the behavioral and psychiatric problems are resolved, drug tapering or discontinuation should be considered in order to prevent life-threatening aspiration pneumonia." @default.
- W2059122751 created "2016-06-24" @default.
- W2059122751 creator A5015932449 @default.
- W2059122751 creator A5026714179 @default.
- W2059122751 creator A5042373488 @default.
- W2059122751 creator A5044059366 @default.
- W2059122751 creator A5071884035 @default.
- W2059122751 creator A5082421988 @default.
- W2059122751 creator A5089308757 @default.
- W2059122751 date "2001-01-01" @default.
- W2059122751 modified "2023-10-13" @default.
- W2059122751 title "Risk Factors of Aspiration Pneumonia in Alzheimer’s Disease Patients" @default.
- W2059122751 cites W1971718948 @default.
- W2059122751 cites W1976845082 @default.
- W2059122751 cites W2065241932 @default.
- W2059122751 cites W2074563815 @default.
- W2059122751 cites W2120080661 @default.
- W2059122751 cites W4230502882 @default.
- W2059122751 doi "https://doi.org/10.1159/000052811" @default.
- W2059122751 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11490146" @default.
- W2059122751 hasPublicationYear "2001" @default.
- W2059122751 type Work @default.
- W2059122751 sameAs 2059122751 @default.
- W2059122751 citedByCount "146" @default.
- W2059122751 countsByYear W20591227512012 @default.
- W2059122751 countsByYear W20591227512013 @default.
- W2059122751 countsByYear W20591227512014 @default.
- W2059122751 countsByYear W20591227512015 @default.
- W2059122751 countsByYear W20591227512016 @default.
- W2059122751 countsByYear W20591227512017 @default.
- W2059122751 countsByYear W20591227512018 @default.
- W2059122751 countsByYear W20591227512019 @default.
- W2059122751 countsByYear W20591227512020 @default.
- W2059122751 countsByYear W20591227512021 @default.
- W2059122751 countsByYear W20591227512022 @default.
- W2059122751 countsByYear W20591227512023 @default.
- W2059122751 crossrefType "journal-article" @default.
- W2059122751 hasAuthorship W2059122751A5015932449 @default.
- W2059122751 hasAuthorship W2059122751A5026714179 @default.
- W2059122751 hasAuthorship W2059122751A5042373488 @default.
- W2059122751 hasAuthorship W2059122751A5044059366 @default.
- W2059122751 hasAuthorship W2059122751A5071884035 @default.
- W2059122751 hasAuthorship W2059122751A5082421988 @default.
- W2059122751 hasAuthorship W2059122751A5089308757 @default.
- W2059122751 hasConcept C112497637 @default.
- W2059122751 hasConcept C126322002 @default.
- W2059122751 hasConcept C141071460 @default.
- W2059122751 hasConcept C156957248 @default.
- W2059122751 hasConcept C2777914695 @default.
- W2059122751 hasConcept C2779134260 @default.
- W2059122751 hasConcept C2779483572 @default.
- W2059122751 hasConcept C2781338923 @default.
- W2059122751 hasConcept C42219234 @default.
- W2059122751 hasConcept C66445296 @default.
- W2059122751 hasConcept C71924100 @default.
- W2059122751 hasConceptScore W2059122751C112497637 @default.
- W2059122751 hasConceptScore W2059122751C126322002 @default.
- W2059122751 hasConceptScore W2059122751C141071460 @default.
- W2059122751 hasConceptScore W2059122751C156957248 @default.
- W2059122751 hasConceptScore W2059122751C2777914695 @default.
- W2059122751 hasConceptScore W2059122751C2779134260 @default.
- W2059122751 hasConceptScore W2059122751C2779483572 @default.
- W2059122751 hasConceptScore W2059122751C2781338923 @default.
- W2059122751 hasConceptScore W2059122751C42219234 @default.
- W2059122751 hasConceptScore W2059122751C66445296 @default.
- W2059122751 hasConceptScore W2059122751C71924100 @default.
- W2059122751 hasIssue "5" @default.
- W2059122751 hasLocation W20591227511 @default.
- W2059122751 hasLocation W20591227512 @default.
- W2059122751 hasOpenAccess W2059122751 @default.
- W2059122751 hasPrimaryLocation W20591227511 @default.
- W2059122751 hasRelatedWork W2090786497 @default.
- W2059122751 hasRelatedWork W2137242336 @default.
- W2059122751 hasRelatedWork W2321723455 @default.
- W2059122751 hasRelatedWork W2336991189 @default.
- W2059122751 hasRelatedWork W2474428000 @default.
- W2059122751 hasRelatedWork W2560644946 @default.
- W2059122751 hasRelatedWork W3036237712 @default.
- W2059122751 hasRelatedWork W3162235096 @default.
- W2059122751 hasRelatedWork W4246201412 @default.
- W2059122751 hasRelatedWork W4295539686 @default.
- W2059122751 hasVolume "47" @default.
- W2059122751 isParatext "false" @default.
- W2059122751 isRetracted "false" @default.
- W2059122751 magId "2059122751" @default.
- W2059122751 workType "article" @default.