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- W2059145675 abstract "A burn injury triggers traumatic reactions characteristics of a stress. Here we investigated the early responses of prolactin (PRL), corticosterone (CS), and signal transducer and activator of transcription 5 (STAT5) in male Sprague-Dawley rats after burn injury. PRL and CS levels were determined in blood serum. STAT5 and phospho-STAT5 levels were determined in jejunum total protein extracts. The results confirmed an expected increase of CS between 4 and 6 h after the burn injury. Unexpectedly, PRL secretion was suppressed during the same time frame. These hormone levels returned to normal 6 to 8 h after burn injury. STAT5 was increased in the jejunum after burn injury, and its phosphorylation was increased between 8 and 11 h after burn injury. These changes in STAT5 were not temporally correlated with either the hormone changes that we observed or with previously documented changes of the gut function after burns." @default.
- W2059145675 created "2016-06-24" @default.
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- W2059145675 date "2001-11-01" @default.
- W2059145675 modified "2023-09-28" @default.
- W2059145675 title "STRESS HORMONE SECRETION AND GUT SIGNAL TRANSDUCER (STAT) PROTEINS AFTER BURN INJURY IN RATS" @default.
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- W2059145675 doi "https://doi.org/10.1097/00024382-200116050-00013" @default.
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