FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059149942> ?p ?o ?g. }

• W2059149942 endingPage "436" @default.
• W2059149942 startingPage "427" @default.
• W2059149942 abstract "We investigated the actions of the neuroactive steroid, pregnanolone [corrected] and the ovarian steroid, 17beta-estradiol, on seizure expression during two time points of ethanol withdrawal (EW). Both steroids can exert rapid, nongenomic actions on the brain that include modulation of seizure activity. Because their basal levels differ in adult males and females and a major symptom of EW is increased seizure risk, we wanted to determine whether these steroids were anticonvulsant during EW. Rats were made ethanol-dependent by administration of 6% ethanol in a nutritionally complete liquid diet for 14 days. After removal of the ethanol-containing diet, EW and paired control rats were tested at 1 or 3 days for seizure responses to pentylenetetrazol. Consistent with previous reports, females seemed to have recovered from EW more quickly than males. We observed significant sex differences in responses to the steroids, primarily at 3 days EW. Pregnanolone afforded protection against seizures with larger effects during EW than in control conditions and greater effects in female than male rats. In contrast, effects of estradiol were mixed. Some responses of ovariectomized female rats were similar to intact females, whereas other responses were more similar to males. Our behavioral findings are consistent with observed EW-induced changes in plasma corticosterone levels, showing persistent elevations in male but not female rats. These results support and extend earlier findings suggesting that although the hormonal milieu influences EW, innate differences in brain structure between the sexes also contribute to sex differences in EW." @default.
• W2059149942 created "2016-06-24" @default.
• W2059149942 creator A5042030501 @default.
• W2059149942 creator A5052608334 @default.
• W2059149942 date "2006-10-04" @default.
• W2059149942 modified "2023-10-04" @default.
• W2059149942 title "Sex Differences in Steroid Modulation of Ethanol Withdrawal in Male and Female Rats" @default.
• W2059149942 cites W1557972708 @default.
• W2059149942 cites W1922154348 @default.
• W2059149942 cites W1983615477 @default.
• W2059149942 cites W1989668336 @default.
• W2059149942 cites W1995357866 @default.
• W2059149942 cites W2009831300 @default.
• W2059149942 cites W2018312248 @default.
• W2059149942 cites W2021903343 @default.
• W2059149942 cites W2023964777 @default.
• W2059149942 cites W2024870023 @default.
• W2059149942 cites W2031161633 @default.
• W2059149942 cites W2035299859 @default.
• W2059149942 cites W2040329969 @default.
• W2059149942 cites W2047869246 @default.
• W2059149942 cites W2052005906 @default.
• W2059149942 cites W2056375261 @default.
• W2059149942 cites W2063059318 @default.
• W2059149942 cites W2074796005 @default.
• W2059149942 cites W2076787408 @default.
• W2059149942 cites W2087897613 @default.
• W2059149942 cites W2090339546 @default.
• W2059149942 cites W2108261924 @default.
• W2059149942 cites W2128408332 @default.
• W2059149942 cites W2131346994 @default.
• W2059149942 cites W2134320754 @default.
• W2059149942 cites W2156566914 @default.
• W2059149942 cites W2615322277 @default.
• W2059149942 cites W4230576299 @default.
• W2059149942 cites W4230966976 @default.
• W2059149942 cites W4245117662 @default.
• W2059149942 cites W4254687453 @default.
• W2059149942 doi "https://doi.org/10.1124/jpet.106.107896" @default.
• W2059149942 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17021261" @default.
• W2059149942 hasPublicationYear "2006" @default.
• W2059149942 type Work @default.
• W2059149942 sameAs 2059149942 @default.
• W2059149942 citedByCount "40" @default.
• W2059149942 countsByYear W20591499422012 @default.
• W2059149942 countsByYear W20591499422013 @default.
• W2059149942 countsByYear W20591499422014 @default.
• W2059149942 countsByYear W20591499422016 @default.
• W2059149942 countsByYear W20591499422017 @default.
• W2059149942 countsByYear W20591499422018 @default.
• W2059149942 countsByYear W20591499422019 @default.
• W2059149942 countsByYear W20591499422021 @default.
• W2059149942 countsByYear W20591499422022 @default.
• W2059149942 countsByYear W20591499422023 @default.
• W2059149942 crossrefType "journal-article" @default.
• W2059149942 hasAuthorship W2059149942A5042030501 @default.
• W2059149942 hasAuthorship W2059149942A5052608334 @default.
• W2059149942 hasConcept C126322002 @default.
• W2059149942 hasConcept C134018914 @default.
• W2059149942 hasConcept C15744967 @default.
• W2059149942 hasConcept C168258287 @default.
• W2059149942 hasConcept C169760540 @default.
• W2059149942 hasConcept C170493617 @default.
• W2059149942 hasConcept C2775858608 @default.
• W2059149942 hasConcept C2776801781 @default.
• W2059149942 hasConcept C2777164284 @default.
• W2059149942 hasConcept C2778024521 @default.
• W2059149942 hasConcept C2778186239 @default.
• W2059149942 hasConcept C2778338918 @default.
• W2059149942 hasConcept C2778460930 @default.
• W2059149942 hasConcept C2779306644 @default.
• W2059149942 hasConcept C2779938979 @default.
• W2059149942 hasConcept C2780161600 @default.
• W2059149942 hasConcept C2780352252 @default.
• W2059149942 hasConcept C2780902042 @default.
• W2059149942 hasConcept C44796713 @default.
• W2059149942 hasConcept C55493867 @default.
• W2059149942 hasConcept C71315377 @default.
• W2059149942 hasConcept C71924100 @default.
• W2059149942 hasConcept C8264082 @default.
• W2059149942 hasConcept C86803240 @default.
• W2059149942 hasConceptScore W2059149942C126322002 @default.
• W2059149942 hasConceptScore W2059149942C134018914 @default.
• W2059149942 hasConceptScore W2059149942C15744967 @default.
• W2059149942 hasConceptScore W2059149942C168258287 @default.
• W2059149942 hasConceptScore W2059149942C169760540 @default.
• W2059149942 hasConceptScore W2059149942C170493617 @default.
• W2059149942 hasConceptScore W2059149942C2775858608 @default.
• W2059149942 hasConceptScore W2059149942C2776801781 @default.
• W2059149942 hasConceptScore W2059149942C2777164284 @default.
• W2059149942 hasConceptScore W2059149942C2778024521 @default.
• W2059149942 hasConceptScore W2059149942C2778186239 @default.
• W2059149942 hasConceptScore W2059149942C2778338918 @default.
• W2059149942 hasConceptScore W2059149942C2778460930 @default.
• W2059149942 hasConceptScore W2059149942C2779306644 @default.
• W2059149942 hasConceptScore W2059149942C2779938979 @default.
• W2059149942 hasConceptScore W2059149942C2780161600 @default.
• W2059149942 hasConceptScore W2059149942C2780352252 @default.

• next