Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059216570> ?p ?o ?g. }
- W2059216570 endingPage "89.e2" @default.
- W2059216570 startingPage "84" @default.
- W2059216570 abstract "To evaluate the epigenetic risk linked to assisted reproductive technology (ART) by analyzing the methylation patterns of imprinted PEG1 gene in aborted human chorionic villus.Experimental research study.Research laboratory.Four patients groups were tested: spontaneous abortion after ART (n = 44), multifetal reduction after ART (n = 22), spontaneous abortion of natural pregnancies (n = 45), and induced abortion of natural pregnancies (n = 47).Methylation patterns of PEG1 in the aborted chorionic villus were determined.The DNA methylation patterns were analyzed using pyrosequencing and bisulfite sequencing polymerase chain reaction. The percentage of methylation was compared in chorionic villus from the four experimental groups.Regardless of conception method, the PEG1 methylation percentage in chorionic villus from spontaneous abortions was significantly higher than in villus from induced abortions and multifetal reduction. In the spontaneous abortions groups, the percent methylation of PEG1 was similar in the villus derived from ART and from natural pregnancies. The two fertilization methods (IVF and intracytoplasmic sperm injection) did not show significant differences either. However, receiver operating characteristic curve analysis revealed a significant positive correlation between PEG1 methylation percentage and rate of early spontaneous abortions.As some studies have suggested, imprinting errors of PEG1 may contribute to spontaneous abortion, but ART procedures might not increase the occurrence of aberrant PEG1 methylation patterns." @default.
- W2059216570 created "2016-06-24" @default.
- W2059216570 creator A5039849025 @default.
- W2059216570 creator A5041125507 @default.
- W2059216570 creator A5046308623 @default.
- W2059216570 creator A5046505184 @default.
- W2059216570 creator A5063580760 @default.
- W2059216570 creator A5072666227 @default.
- W2059216570 date "2011-07-01" @default.
- W2059216570 modified "2023-10-02" @default.
- W2059216570 title "Assisted reproductive technologies do not increase risk of abnormal methylation of PEG1/MEST in human early pregnancy loss" @default.
- W2059216570 cites W1533935872 @default.
- W2059216570 cites W1590914074 @default.
- W2059216570 cites W1961597426 @default.
- W2059216570 cites W1967064280 @default.
- W2059216570 cites W1972612324 @default.
- W2059216570 cites W2001481979 @default.
- W2059216570 cites W2009533183 @default.
- W2059216570 cites W2009546483 @default.
- W2059216570 cites W2011354757 @default.
- W2059216570 cites W2044894134 @default.
- W2059216570 cites W2049153989 @default.
- W2059216570 cites W2050592293 @default.
- W2059216570 cites W2061198729 @default.
- W2059216570 cites W2081064915 @default.
- W2059216570 cites W2084279635 @default.
- W2059216570 cites W2087062266 @default.
- W2059216570 cites W2088435866 @default.
- W2059216570 cites W2092270599 @default.
- W2059216570 cites W2100604823 @default.
- W2059216570 cites W2103246764 @default.
- W2059216570 cites W2105323880 @default.
- W2059216570 cites W2112017997 @default.
- W2059216570 cites W2113068058 @default.
- W2059216570 cites W2115589133 @default.
- W2059216570 cites W2127905342 @default.
- W2059216570 cites W2135729860 @default.
- W2059216570 cites W2144597014 @default.
- W2059216570 cites W2146737098 @default.
- W2059216570 cites W2148016791 @default.
- W2059216570 cites W2149922901 @default.
- W2059216570 cites W2150695051 @default.
- W2059216570 cites W2162303623 @default.
- W2059216570 cites W2167020978 @default.
- W2059216570 cites W2169798600 @default.
- W2059216570 cites W4210368595 @default.
- W2059216570 cites W4211031227 @default.
- W2059216570 cites W4242613759 @default.
- W2059216570 cites W4253876192 @default.
- W2059216570 doi "https://doi.org/10.1016/j.fertnstert.2011.04.021" @default.
- W2059216570 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21575949" @default.
- W2059216570 hasPublicationYear "2011" @default.
- W2059216570 type Work @default.
- W2059216570 sameAs 2059216570 @default.
- W2059216570 citedByCount "26" @default.
- W2059216570 countsByYear W20592165702012 @default.
- W2059216570 countsByYear W20592165702013 @default.
- W2059216570 countsByYear W20592165702014 @default.
- W2059216570 countsByYear W20592165702016 @default.
- W2059216570 countsByYear W20592165702017 @default.
- W2059216570 countsByYear W20592165702018 @default.
- W2059216570 countsByYear W20592165702019 @default.
- W2059216570 countsByYear W20592165702020 @default.
- W2059216570 countsByYear W20592165702021 @default.
- W2059216570 countsByYear W20592165702022 @default.
- W2059216570 countsByYear W20592165702023 @default.
- W2059216570 crossrefType "journal-article" @default.
- W2059216570 hasAuthorship W2059216570A5039849025 @default.
- W2059216570 hasAuthorship W2059216570A5041125507 @default.
- W2059216570 hasAuthorship W2059216570A5046308623 @default.
- W2059216570 hasAuthorship W2059216570A5046505184 @default.
- W2059216570 hasAuthorship W2059216570A5063580760 @default.
- W2059216570 hasAuthorship W2059216570A5072666227 @default.
- W2059216570 hasBestOaLocation W20592165701 @default.
- W2059216570 hasConcept C104317684 @default.
- W2059216570 hasConcept C131872663 @default.
- W2059216570 hasConcept C150194340 @default.
- W2059216570 hasConcept C16685009 @default.
- W2059216570 hasConcept C172680121 @default.
- W2059216570 hasConcept C190727270 @default.
- W2059216570 hasConcept C201492766 @default.
- W2059216570 hasConcept C2776555163 @default.
- W2059216570 hasConcept C2776953305 @default.
- W2059216570 hasConcept C2778278907 @default.
- W2059216570 hasConcept C2778279030 @default.
- W2059216570 hasConcept C2778642596 @default.
- W2059216570 hasConcept C2779234561 @default.
- W2059216570 hasConcept C2780340734 @default.
- W2059216570 hasConcept C2781385326 @default.
- W2059216570 hasConcept C29456083 @default.
- W2059216570 hasConcept C3019714739 @default.
- W2059216570 hasConcept C33288867 @default.
- W2059216570 hasConcept C41091548 @default.
- W2059216570 hasConcept C512716672 @default.
- W2059216570 hasConcept C54355233 @default.
- W2059216570 hasConcept C71924100 @default.
- W2059216570 hasConcept C86803240 @default.
- W2059216570 hasConceptScore W2059216570C104317684 @default.