Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059249994> ?p ?o ?g. }
- W2059249994 endingPage "64" @default.
- W2059249994 startingPage "55" @default.
- W2059249994 abstract "The β-turn, which has also been referred to as the β-bend, β-loop or reverse turn, has been implicated as an important site for molecular recognition in many biologically active peptides and in globular proteins. This small secondary structure therefore makes an attractive target for mimicry by a conformational constraint, because a peptide which is constrained in a biologically active conformation can display a number of advantages over the parent substrate. The less peptide-like such a constraint is, the more potential there is to maximize these advantages. A decade has passed since the first (and highly successful) attempt to mimic the β-turn with a nonpeptide conformational constraint was disclosed by Freidinger et al. (1980). Since this report, rapidly growing interest in the field of nonpeptide β-turn mimics has seen a variety of experimental approaches and a mixed bag of results. It is attempted in this review, not only to summarize and critically analyse these approaches, but also to touch on the compexities associated with the conformational mimicry of such a diverse structure as the β-turn." @default.
- W2059249994 created "2016-06-24" @default.
- W2059249994 creator A5058316270 @default.
- W2059249994 creator A5066271465 @default.
- W2059249994 date "1990-04-01" @default.
- W2059249994 modified "2023-10-08" @default.
- W2059249994 title "Conformational constraints: Nonpeptide β-turn mimics" @default.
- W2059249994 cites W1544623810 @default.
- W2059249994 cites W157901186 @default.
- W2059249994 cites W1586022877 @default.
- W2059249994 cites W1606912375 @default.
- W2059249994 cites W1967841252 @default.
- W2059249994 cites W1967881203 @default.
- W2059249994 cites W1974131192 @default.
- W2059249994 cites W1979384103 @default.
- W2059249994 cites W1981994818 @default.
- W2059249994 cites W1984640820 @default.
- W2059249994 cites W1984710000 @default.
- W2059249994 cites W2004732735 @default.
- W2059249994 cites W2005430782 @default.
- W2059249994 cites W2005798472 @default.
- W2059249994 cites W2012716149 @default.
- W2059249994 cites W2016645206 @default.
- W2059249994 cites W2025822492 @default.
- W2059249994 cites W2029453167 @default.
- W2059249994 cites W2031471354 @default.
- W2059249994 cites W2035383798 @default.
- W2059249994 cites W2036899726 @default.
- W2059249994 cites W2037980432 @default.
- W2059249994 cites W2038147123 @default.
- W2059249994 cites W2038576827 @default.
- W2059249994 cites W2053721311 @default.
- W2059249994 cites W2063863091 @default.
- W2059249994 cites W2066581720 @default.
- W2059249994 cites W2066686002 @default.
- W2059249994 cites W2069718511 @default.
- W2059249994 cites W2076444581 @default.
- W2059249994 cites W2086313661 @default.
- W2059249994 cites W2086872133 @default.
- W2059249994 cites W2094367021 @default.
- W2059249994 cites W2094629373 @default.
- W2059249994 cites W2097175042 @default.
- W2059249994 cites W2113403117 @default.
- W2059249994 cites W2126533930 @default.
- W2059249994 cites W2134493125 @default.
- W2059249994 cites W2319721029 @default.
- W2059249994 cites W2402987469 @default.
- W2059249994 doi "https://doi.org/10.1002/jmr.300030202" @default.
- W2059249994 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2163268" @default.
- W2059249994 hasPublicationYear "1990" @default.
- W2059249994 type Work @default.
- W2059249994 sameAs 2059249994 @default.
- W2059249994 citedByCount "124" @default.
- W2059249994 countsByYear W20592499942012 @default.
- W2059249994 countsByYear W20592499942013 @default.
- W2059249994 countsByYear W20592499942014 @default.
- W2059249994 countsByYear W20592499942015 @default.
- W2059249994 countsByYear W20592499942016 @default.
- W2059249994 countsByYear W20592499942017 @default.
- W2059249994 countsByYear W20592499942018 @default.
- W2059249994 countsByYear W20592499942021 @default.
- W2059249994 countsByYear W20592499942022 @default.
- W2059249994 countsByYear W20592499942023 @default.
- W2059249994 crossrefType "journal-article" @default.
- W2059249994 hasAuthorship W2059249994A5058316270 @default.
- W2059249994 hasAuthorship W2059249994A5066271465 @default.
- W2059249994 hasConcept C127413603 @default.
- W2059249994 hasConcept C147483822 @default.
- W2059249994 hasConcept C185592680 @default.
- W2059249994 hasConcept C18903297 @default.
- W2059249994 hasConcept C2776036281 @default.
- W2059249994 hasConcept C2777119779 @default.
- W2059249994 hasConcept C2777339483 @default.
- W2059249994 hasConcept C2779281246 @default.
- W2059249994 hasConcept C41008148 @default.
- W2059249994 hasConcept C47701112 @default.
- W2059249994 hasConcept C54355233 @default.
- W2059249994 hasConcept C55493867 @default.
- W2059249994 hasConcept C70721500 @default.
- W2059249994 hasConcept C78519656 @default.
- W2059249994 hasConcept C7863114 @default.
- W2059249994 hasConcept C85641259 @default.
- W2059249994 hasConcept C86803240 @default.
- W2059249994 hasConceptScore W2059249994C127413603 @default.
- W2059249994 hasConceptScore W2059249994C147483822 @default.
- W2059249994 hasConceptScore W2059249994C185592680 @default.
- W2059249994 hasConceptScore W2059249994C18903297 @default.
- W2059249994 hasConceptScore W2059249994C2776036281 @default.
- W2059249994 hasConceptScore W2059249994C2777119779 @default.
- W2059249994 hasConceptScore W2059249994C2777339483 @default.
- W2059249994 hasConceptScore W2059249994C2779281246 @default.
- W2059249994 hasConceptScore W2059249994C41008148 @default.
- W2059249994 hasConceptScore W2059249994C47701112 @default.
- W2059249994 hasConceptScore W2059249994C54355233 @default.
- W2059249994 hasConceptScore W2059249994C55493867 @default.
- W2059249994 hasConceptScore W2059249994C70721500 @default.
- W2059249994 hasConceptScore W2059249994C78519656 @default.
- W2059249994 hasConceptScore W2059249994C7863114 @default.