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- W2059280015 abstract "Mass vaccination was the most effective prophylaxis for protecting the population during the influenza H1N1 pandemic. We have evaluated the tolerability, immunogenicity and kinetics of the antibody response to a monovalent oil-in-water (AS03) adjuvanted human pandemic split influenza A/California/7/2009 H1N1 (3.75 μg haemagglutinin) vaccine in health care workers. Vaccination elicited a rapid and early protective level of haemagglutination inhibition antibody from 6 to 7 days post vaccination, and by 14 to 21 days post vaccination, up to 98% of vaccinees had protective antibody titres which persisted for at least 3 months in 84–92% of subjects. A rapid induction of protective antibody is important in reducing community spread of pandemic influenza and in helping maintain the integrity of the health care system during the pandemic." @default.
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- W2059280015 date "2010-12-01" @default.
- W2059280015 modified "2023-09-25" @default.
- W2059280015 title "An adjuvanted pandemic influenza H1N1 vaccine provides early and long term protection in health care workers" @default.
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- W2059280015 doi "https://doi.org/10.1016/j.vaccine.2010.10.038" @default.
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