Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059280858> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2059280858 endingPage "1239" @default.
- W2059280858 startingPage "1234" @default.
- W2059280858 abstract "Sensitive specific methods are described for the determination of phenylbutazone and its metabolite oxyphenbutazone from the same plasma sample. The sample, to which an internal standard 5-(4-hydroxyphenyl)-5-phenylhydantoin (Standard II) is added, is first extracted with ether to remove interfering substances and then with n-heptane under acidic conditions to separate phenylbutazone, which is determined on a gas chromatograph by flash methylation (310°) with trimethylanilinium hydroxide using 1-(o-chlorophenyl)-1-(p-chlorophenyl)-2,2,2-trichloroethane as the external standard (Standard I). The aqueous acidic residue from which the phenylbutazone has been selectively removed is shaken again with ether to extract the oxyphenbutazone, which is analyzed with a different GLC system with flash methylation (310°) against Standard II. The methods are of sufficient sensitivity to determine plasma levels in humans after a 200-mg dose of phenylbutazone (phenylbutazone, 1 μg/ml; oxyphenbutazone, 0.5 μ/gml)." @default.
- W2059280858 created "2016-06-24" @default.
- W2059280858 creator A5014715117 @default.
- W2059280858 creator A5040764890 @default.
- W2059280858 creator A5091850136 @default.
- W2059280858 date "1974-08-01" @default.
- W2059280858 modified "2023-09-25" @default.
- W2059280858 title "GLC Determination of Plasma Concentration of Phenylbutazone and its Metabolite Oxyphenbutazone" @default.
- W2059280858 cites W1906399634 @default.
- W2059280858 cites W1986701023 @default.
- W2059280858 cites W2000989481 @default.
- W2059280858 cites W2011313186 @default.
- W2059280858 cites W2035695259 @default.
- W2059280858 cites W2037039993 @default.
- W2059280858 cites W2064732440 @default.
- W2059280858 cites W2085981322 @default.
- W2059280858 doi "https://doi.org/10.1002/jps.2600630814" @default.
- W2059280858 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4852201" @default.
- W2059280858 hasPublicationYear "1974" @default.
- W2059280858 type Work @default.
- W2059280858 sameAs 2059280858 @default.
- W2059280858 citedByCount "26" @default.
- W2059280858 countsByYear W20592808582014 @default.
- W2059280858 crossrefType "journal-article" @default.
- W2059280858 hasAuthorship W2059280858A5014715117 @default.
- W2059280858 hasAuthorship W2059280858A5040764890 @default.
- W2059280858 hasAuthorship W2059280858A5091850136 @default.
- W2059280858 hasConcept C178790620 @default.
- W2059280858 hasConcept C185592680 @default.
- W2059280858 hasConcept C2775844104 @default.
- W2059280858 hasConcept C2775896084 @default.
- W2059280858 hasConcept C2776148806 @default.
- W2059280858 hasConcept C2777477808 @default.
- W2059280858 hasConcept C2777837344 @default.
- W2059280858 hasConcept C2780407432 @default.
- W2059280858 hasConcept C43617362 @default.
- W2059280858 hasConcept C4725764 @default.
- W2059280858 hasConcept C55493867 @default.
- W2059280858 hasConcept C71924100 @default.
- W2059280858 hasConcept C98274493 @default.
- W2059280858 hasConceptScore W2059280858C178790620 @default.
- W2059280858 hasConceptScore W2059280858C185592680 @default.
- W2059280858 hasConceptScore W2059280858C2775844104 @default.
- W2059280858 hasConceptScore W2059280858C2775896084 @default.
- W2059280858 hasConceptScore W2059280858C2776148806 @default.
- W2059280858 hasConceptScore W2059280858C2777477808 @default.
- W2059280858 hasConceptScore W2059280858C2777837344 @default.
- W2059280858 hasConceptScore W2059280858C2780407432 @default.
- W2059280858 hasConceptScore W2059280858C43617362 @default.
- W2059280858 hasConceptScore W2059280858C4725764 @default.
- W2059280858 hasConceptScore W2059280858C55493867 @default.
- W2059280858 hasConceptScore W2059280858C71924100 @default.
- W2059280858 hasConceptScore W2059280858C98274493 @default.
- W2059280858 hasIssue "8" @default.
- W2059280858 hasLocation W20592808581 @default.
- W2059280858 hasLocation W20592808582 @default.
- W2059280858 hasOpenAccess W2059280858 @default.
- W2059280858 hasPrimaryLocation W20592808581 @default.
- W2059280858 hasRelatedWork W2010057523 @default.
- W2059280858 hasRelatedWork W2015504800 @default.
- W2059280858 hasRelatedWork W2039353798 @default.
- W2059280858 hasRelatedWork W2043868760 @default.
- W2059280858 hasRelatedWork W2081633158 @default.
- W2059280858 hasRelatedWork W2133118705 @default.
- W2059280858 hasRelatedWork W2157669900 @default.
- W2059280858 hasRelatedWork W2161405337 @default.
- W2059280858 hasRelatedWork W2325001668 @default.
- W2059280858 hasRelatedWork W2401994906 @default.
- W2059280858 hasVolume "63" @default.
- W2059280858 isParatext "false" @default.
- W2059280858 isRetracted "false" @default.
- W2059280858 magId "2059280858" @default.
- W2059280858 workType "article" @default.