FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059282647> ?p ?o ?g. }

• W2059282647 endingPage "867" @default.
• W2059282647 startingPage "853" @default.
• W2059282647 abstract "Localization of human quantitative trait loci (QTLs) is now routine. However, identifying their functional DNA variants is still a formidable challenge. We present a complete dissection of a human QTL using novel statistical techniques to infer the most likely functional polymorphisms of a QTL that influence plasma levels of clotting factor VII (FVII), a risk factor for cardiovascular disease. Resequencing of 15 kb in and around the F7 gene identified 49 polymorphisms, which were then genotyped in 398 people. Using a Bayesian quantitative trait nucleotide (BQTN) method, we identified four to seven functional variants that completely account for this QTL. These variants include both rare coding variants and more common, potentially regulatory polymorphisms in intronic and promoter regions." @default.
• W2059282647 created "2016-06-24" @default.
• W2059282647 creator A5001935511 @default.
• W2059282647 creator A5004538115 @default.
• W2059282647 creator A5028529427 @default.
• W2059282647 creator A5043180844 @default.
• W2059282647 creator A5061057305 @default.
• W2059282647 creator A5087753151 @default.
• W2059282647 date "2009-12-01" @default.
• W2059282647 modified "2023-09-29" @default.
• W2059282647 title "The F7 Gene and Clotting Factor VII Levels: Dissection of a Human Quantitative Trait Locus" @default.
• W2059282647 cites W1516853780 @default.
• W2059282647 cites W1879255485 @default.
• W2059282647 cites W191965805 @default.
• W2059282647 cites W1966875441 @default.
• W2059282647 cites W1973415209 @default.
• W2059282647 cites W1976114496 @default.
• W2059282647 cites W2001003226 @default.
• W2059282647 cites W2036363775 @default.
• W2059282647 cites W2051825012 @default.
• W2059282647 cites W2054881132 @default.
• W2059282647 cites W2055198158 @default.
• W2059282647 cites W2062318434 @default.
• W2059282647 cites W2065204703 @default.
• W2059282647 cites W2065228714 @default.
• W2059282647 cites W2082523755 @default.
• W2059282647 cites W2084124265 @default.
• W2059282647 cites W2105306382 @default.
• W2059282647 cites W2115335486 @default.
• W2059282647 cites W2121186771 @default.
• W2059282647 cites W2124423915 @default.
• W2059282647 cites W2127472986 @default.
• W2059282647 cites W2149221304 @default.
• W2059282647 cites W2152664025 @default.
• W2059282647 cites W2165670210 @default.
• W2059282647 cites W2335785294 @default.
• W2059282647 cites W2336612658 @default.
• W2059282647 cites W2397098917 @default.
• W2059282647 cites W2409571859 @default.
• W2059282647 cites W2411696643 @default.
• W2059282647 cites W2414185646 @default.
• W2059282647 cites W2417706951 @default.
• W2059282647 doi "https://doi.org/10.3378/027.081.0627" @default.
• W2059282647 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20504202" @default.
• W2059282647 hasPublicationYear "2009" @default.
• W2059282647 type Work @default.
• W2059282647 sameAs 2059282647 @default.
• W2059282647 citedByCount "22" @default.
• W2059282647 countsByYear W20592826472014 @default.
• W2059282647 countsByYear W20592826472016 @default.
• W2059282647 countsByYear W20592826472017 @default.
• W2059282647 countsByYear W20592826472018 @default.
• W2059282647 countsByYear W20592826472023 @default.
• W2059282647 crossrefType "journal-article" @default.
• W2059282647 hasAuthorship W2059282647A5001935511 @default.
• W2059282647 hasAuthorship W2059282647A5004538115 @default.
• W2059282647 hasAuthorship W2059282647A5028529427 @default.
• W2059282647 hasAuthorship W2059282647A5043180844 @default.
• W2059282647 hasAuthorship W2059282647A5061057305 @default.
• W2059282647 hasAuthorship W2059282647A5087753151 @default.
• W2059282647 hasConcept C104317684 @default.
• W2059282647 hasConcept C106934330 @default.
• W2059282647 hasConcept C122735190 @default.
• W2059282647 hasConcept C126322002 @default.
• W2059282647 hasConcept C135763542 @default.
• W2059282647 hasConcept C153209595 @default.
• W2059282647 hasConcept C199360897 @default.
• W2059282647 hasConcept C21249469 @default.
• W2059282647 hasConcept C2992139802 @default.
• W2059282647 hasConcept C30481170 @default.
• W2059282647 hasConcept C41008148 @default.
• W2059282647 hasConcept C54355233 @default.
• W2059282647 hasConcept C70721500 @default.
• W2059282647 hasConcept C71924100 @default.
• W2059282647 hasConcept C81941488 @default.
• W2059282647 hasConcept C84597430 @default.
• W2059282647 hasConcept C86803240 @default.
• W2059282647 hasConceptScore W2059282647C104317684 @default.
• W2059282647 hasConceptScore W2059282647C106934330 @default.
• W2059282647 hasConceptScore W2059282647C122735190 @default.
• W2059282647 hasConceptScore W2059282647C126322002 @default.
• W2059282647 hasConceptScore W2059282647C135763542 @default.
• W2059282647 hasConceptScore W2059282647C153209595 @default.
• W2059282647 hasConceptScore W2059282647C199360897 @default.
• W2059282647 hasConceptScore W2059282647C21249469 @default.
• W2059282647 hasConceptScore W2059282647C2992139802 @default.
• W2059282647 hasConceptScore W2059282647C30481170 @default.
• W2059282647 hasConceptScore W2059282647C41008148 @default.
• W2059282647 hasConceptScore W2059282647C54355233 @default.
• W2059282647 hasConceptScore W2059282647C70721500 @default.
• W2059282647 hasConceptScore W2059282647C71924100 @default.
• W2059282647 hasConceptScore W2059282647C81941488 @default.
• W2059282647 hasConceptScore W2059282647C84597430 @default.
• W2059282647 hasConceptScore W2059282647C86803240 @default.
• W2059282647 hasIssue "5-6" @default.
• W2059282647 hasLocation W20592826471 @default.
• W2059282647 hasLocation W20592826472 @default.
• W2059282647 hasOpenAccess W2059282647 @default.

• next