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- W2059284187 abstract "Globularia aphyllanthes (Plantaginaceae) is a perennial plant, distributed from northwest Turkey to central and southern Europe [1]. Some members of the genus Globularia are used as hypoglycaemic, laxative, cholagogue and for the treatment of haemorrhoids in the folk medicines of some Mediterranean countries [2,3]. It has only been investigated for its iridoid contents so far [4]. In the continuation of our work on secondary metabolites of the genus Globularia from Turkey, we have isolated a new flavone glycoside, 6-hydroxyluteolin 7-O-[6'''-benzoyl-β-D-glucopyranosyl-(1→2)]-β-D-glucopyranoside (1) from the MeOH extract of the aerial parts of G. aphyllanthes. Besides this new compound, a flavonol glycoside, isoquercitrin, three phenylethanoid glycosides (verbascoside, rossicaside A, and trichosanthoside A), and seven iridoid glycosides (catalpol, globularin, asperuloside, besperuloside, asperulosidic acid, scandoside, and baldaccioside) were also obtained and characterized. Identification of the isolated compounds was carried out by spectroscopic analysis including 1D and 2D NMR experiments as well as HR-MS. The chlorinated iridoid glycoside, baldaccioside, was isolated for the first time from the genus Globularia, while its C-7 epimer was reported from G. alypum [5]." @default.
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- W2059284187 date "2008-07-01" @default.
- W2059284187 modified "2023-09-27" @default.
- W2059284187 title "Flavonoid, phenylethanoid and iridoid glycosides from Globularia aphyllanthes" @default.
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- W2059284187 doi "https://doi.org/10.1055/s-0028-1084397" @default.
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