FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059294089> ?p ?o ?g. }

• W2059294089 endingPage "1049" @default.
• W2059294089 startingPage "1041" @default.
• W2059294089 abstract "To comparatively analyse the expression of matrix metalloproteinase (MMP-3) and tissue inhibitor of MMP (TIMP-2) in serosal tissue of intraperitoneal organs and adhesions, as well as peritoneal fluid and serum of subjects with and without adhesions.Cross sectional study.Academic research centres.Patients undergoing abdominal/pelvic surgery.Messenger ribonucleic acid (mRNA) and protein expression using quantitative reverse transcription polymerase chain reaction (Q-RT-PCR), ELISA and immunohistochemistry.All the tissues examined express MMP-3 and TIMP-2 mRNA and protein at consistently varying levels ranging from 100- to 1000-fold and 2- to 10-fold mRNA and protein, respectively. Serosa of uterine, fallopian tube, ovary and partial peritoneum express a higher MMP-3 mRNA compared with small and large bowels and omentum, while TIMP-2 expression was less variable with the highest level found in uterine serosa (P < 0.05). The expression of MMP-3 and TIMP-2 mRNA in adhesions was not significantly different compared with parietal peritoneum. MMP-3 and TIMP-2 protein content in tissue extracts, peritoneal fluids and serum also varied with higher TIMP-2 than MMP-3 (P < 0.05). TIMP-2 levels were lower in serum of subjects with moderate/extensive adhesions compared with subjects without adhesions. Immunoreactive MMP-3 and TIMP-2 proteins were detected in various cell types in these tissues. There was no correlation between MMP-3 and TIMP-2 expression, and age, gender or menstrual status of subjects with or without adhesions.MMP-3 and TIMP-2 are expressed at varying levels in serosal tissues of peritoneal organs and adhesions, with higher TIMP-2 than MMP-3. Based on the knowledge that tissue injury alters the expression of MMPs and TIMPs, such variations may predispose an organ to develop more adhesions than others. In addition, the results suggest that serum level of TIMP-2 may represent a marker for subjects who will form adhesions with greater severity." @default.
• W2059294089 created "2016-06-24" @default.
• W2059294089 creator A5001512334 @default.
• W2059294089 creator A5005306051 @default.
• W2059294089 creator A5024519937 @default.
• W2059294089 creator A5026210823 @default.
• W2059294089 creator A5031138425 @default.
• W2059294089 creator A5036939102 @default.
• W2059294089 creator A5042465225 @default.
• W2059294089 creator A5072487711 @default.
• W2059294089 date "2002-09-01" @default.
• W2059294089 modified "2023-09-24" @default.
• W2059294089 title "Differential expression of matrix metalloproteinase and tissue inhibitor of MMP in serosal tissue of intraperitoneal organs and adhesions" @default.
• W2059294089 cites W1487863786 @default.
• W2059294089 cites W1837228878 @default.
• W2059294089 cites W1964386731 @default.
• W2059294089 cites W1969817378 @default.
• W2059294089 cites W1973135358 @default.
• W2059294089 cites W1974659386 @default.
• W2059294089 cites W1982365221 @default.
• W2059294089 cites W1983767783 @default.
• W2059294089 cites W1988327100 @default.
• W2059294089 cites W1996647701 @default.
• W2059294089 cites W1998749549 @default.
• W2059294089 cites W2014656456 @default.
• W2059294089 cites W2015031004 @default.
• W2059294089 cites W2022836911 @default.
• W2059294089 cites W2028147193 @default.
• W2059294089 cites W2040435028 @default.
• W2059294089 cites W2056105344 @default.
• W2059294089 cites W2056420432 @default.
• W2059294089 cites W2060709653 @default.
• W2059294089 cites W2062023732 @default.
• W2059294089 cites W2078965696 @default.
• W2059294089 cites W2083533326 @default.
• W2059294089 cites W2087239912 @default.
• W2059294089 cites W2108144590 @default.
• W2059294089 cites W2114740351 @default.
• W2059294089 cites W2116980521 @default.
• W2059294089 cites W2119963981 @default.
• W2059294089 cites W2122362756 @default.
• W2059294089 cites W2137937804 @default.
• W2059294089 cites W2150365936 @default.
• W2059294089 cites W2165377772 @default.
• W2059294089 cites W2172070403 @default.
• W2059294089 cites W2593318548 @default.
• W2059294089 cites W3168182028 @default.
• W2059294089 cites W4230756497 @default.
• W2059294089 cites W4250908540 @default.
• W2059294089 doi "https://doi.org/10.1111/j.1471-0528.2002.01334.x" @default.
• W2059294089 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12269680" @default.
• W2059294089 hasPublicationYear "2002" @default.
• W2059294089 type Work @default.
• W2059294089 sameAs 2059294089 @default.
• W2059294089 citedByCount "21" @default.
• W2059294089 countsByYear W20592940892012 @default.
• W2059294089 countsByYear W20592940892013 @default.
• W2059294089 countsByYear W20592940892017 @default.
• W2059294089 countsByYear W20592940892019 @default.
• W2059294089 countsByYear W20592940892020 @default.
• W2059294089 countsByYear W20592940892021 @default.
• W2059294089 countsByYear W20592940892022 @default.
• W2059294089 crossrefType "journal-article" @default.
• W2059294089 hasAuthorship W2059294089A5001512334 @default.
• W2059294089 hasAuthorship W2059294089A5005306051 @default.
• W2059294089 hasAuthorship W2059294089A5024519937 @default.
• W2059294089 hasAuthorship W2059294089A5026210823 @default.
• W2059294089 hasAuthorship W2059294089A5031138425 @default.
• W2059294089 hasAuthorship W2059294089A5036939102 @default.
• W2059294089 hasAuthorship W2059294089A5042465225 @default.
• W2059294089 hasAuthorship W2059294089A5072487711 @default.
• W2059294089 hasConcept C104317684 @default.
• W2059294089 hasConcept C105580179 @default.
• W2059294089 hasConcept C109523444 @default.
• W2059294089 hasConcept C126322002 @default.
• W2059294089 hasConcept C142724271 @default.
• W2059294089 hasConcept C16685009 @default.
• W2059294089 hasConcept C204232928 @default.
• W2059294089 hasConcept C2775965246 @default.
• W2059294089 hasConcept C2776001837 @default.
• W2059294089 hasConcept C55493867 @default.
• W2059294089 hasConcept C71924100 @default.
• W2059294089 hasConcept C86803240 @default.
• W2059294089 hasConceptScore W2059294089C104317684 @default.
• W2059294089 hasConceptScore W2059294089C105580179 @default.
• W2059294089 hasConceptScore W2059294089C109523444 @default.
• W2059294089 hasConceptScore W2059294089C126322002 @default.
• W2059294089 hasConceptScore W2059294089C142724271 @default.
• W2059294089 hasConceptScore W2059294089C16685009 @default.
• W2059294089 hasConceptScore W2059294089C204232928 @default.
• W2059294089 hasConceptScore W2059294089C2775965246 @default.
• W2059294089 hasConceptScore W2059294089C2776001837 @default.
• W2059294089 hasConceptScore W2059294089C55493867 @default.
• W2059294089 hasConceptScore W2059294089C71924100 @default.
• W2059294089 hasConceptScore W2059294089C86803240 @default.
• W2059294089 hasIssue "9" @default.
• W2059294089 hasLocation W20592940891 @default.
• W2059294089 hasLocation W20592940892 @default.

• next