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• W2059296989 abstract "The dysmyelinating mouse mutant Shiverer has a severe and relatively selective deficiency of myelin basic protein (MBP) in the central and peripheral nervous system. Nevertheless, Shiverer brain and control-mouse brain showed similar antigenic titers when tested by a complement fixation assay against a panel of 14 multiple sclerosis (MS) sera and 6 MS CSF samples known to represent several specificities of antibrain antibodies. By analogy with experimental allergic encephalomyelitis, a sensitization to MBP has been proposed in MS. Our results, however, show that antibodies to other CNS antigens are quantitatively more important in this disease." @default.
• W2059296989 created "2016-06-24" @default.
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• W2059296989 date "2009-01-29" @default.
• W2059296989 modified "2023-09-23" @default.
• W2059296989 title "Are anti-brain antibodies in multiple sclerosis directed to myelin basic protein? Studies employing the Shiverer mouse mutant" @default.
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• W2059296989 doi "https://doi.org/10.1111/j.1600-0404.1986.tb03270.x" @default.
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