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• W2059299218 abstract "Las neoplasias malignas son la segunda causa de muerte en los países desarrollados, por detrás de las enfermedades cardiovasculares, y ambas entidades tienen factores en común.Estudio prospectivo de todos los pacientes ingresados por un síndrome coronario agudo en el que se evaluó la prevalencia de neoplasias y la incidencia tras el alta.La prevalencia de neoplasias en los 1.819 pacientes incluidos fue del 3,4% y el 41,9% de los casos se consideraron libres de enfermedad. Entre los 1.731 pacientes dados de alta, la incidencia fue 3,1% (53 casos) y las localizaciones más frecuentes fueron colon, pulmón, vejiga y páncreas. Los pacientes con neoplasias prevalentes presentaron más edad, comorbilidades y complicaciones. No se observaron diferencias en el porcentaje de revascularización, pero sí menor uso de stents farmacoactivos en los pacientes con neoplasias prevalentes. Durante el seguimiento, la mediana de tiempo hasta el diagnóstico de nuevas neoplasias fue de 25 meses y el análisis multivariante identificó como factores independientes la edad y el ser fumador o exfumador. La mortalidad por cualquier causa tras el alta fue muy superior en los pacientes con neoplasias incidentes (64,2%) o prevalentes (40,0%). El análisis multivariante mostró que en las neoplasias prevalentes e incidentes se multiplicaba por 4 el riesgo de mortalidad por cualquier causa.El 3,8% de los pacientes tuvieron neoplasias prevalentes y menos del 50% se consideraban curadas en el momento del ingreso. La incidencia de nuevas neoplasias fue del 3,4% y ambas formas de neoplasias empeoraron mucho el pronóstico a largo plazo.Malignancies are the second cause of death in developed countries after cardiovascular disease and both share common risk factors.This prospective study assessed the prevalence and postdischarge incidence of malignancies in all consecutive patients admitted for an acute coronary syndrome.A total of 1819 patients were included. On admission, the prevalence of malignancies was 3.4%, and 41.9% of the patients were considered disease-free; of the 1731 discharged patients, the incidence was 3.1% (53 cases) and the most common locations were the colon, lung, bladder, and pancreas. Patients with prevalent malignancies were older and had more comorbidities and complications. There were no differences in the revascularization rate, but implantation of drug-eluting stents was less frequent in patients with prevalent malignancies. During follow-up, the median time to diagnosis of incident malignancies was 25 months. On multivariate analysis, independent risk factors were age and current or former smoking. All-cause mortality was much higher in patients with incident (64.2%) or prevalent (40.0%) malignancies. Multivariate analysis showed that prevalent and incident malignancies increased the risk of all-cause mortality by 4-fold.Among patients admitted for an acute coronary syndrome, 3.8% had a history of malignancy, with less than 50% considered cured. The incidence of new malignancies was 3.4% and both types of malignancies substantially impaired the long-term prognosis.Full English text available from: www.revespcardiol.org/en" @default.
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• W2059299218 date "2012-10-01" @default.
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• W2059299218 title "Comentarios a la guía de práctica clínica de la ESC sobre prevención de la enfermedad cardiovascular (versión 2012). Un informe del Grupo de Trabajo del Comité de Guías de Práctica Clínica de la Sociedad Española de Cardiología" @default.
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• W2059299218 doi "https://doi.org/10.1016/j.recesp.2012.08.001" @default.
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