FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059314248> ?p ?o ?g. }

• W2059314248 endingPage "521" @default.
• W2059314248 startingPage "512" @default.
• W2059314248 abstract "The purpose of this study was to evaluate in a prospective, double-blind, placebo-controlled study the effect of long-term (2-year) lisinopril treatment on cardiovascular end-organ damage in patients with previously untreated isolated systolic hypertension (ISH). All patients with ISH were derived from a population screening program. End-organ damage measurements, done initially and after 6 and 24 months of treatment, included measurements of aortic distensibility and echocardiographic left ventricular mass index (LVMI) and diastolic function. Blood pressure was measured by office and ambulatory measurements. Of the 97 subjects with ISH selected from the screening, 62 (30 lisinopril) completed the study according to protocol. Office blood pressure decreased in both groups, but ambulatory results significantly decreased with lisinopril-treatment only. Aortic distensibility increased significantly with lisinopril, as opposed to a decrease in placebo-treated subjects. The main effect of increased distensibility occurred between 6 and 24 months, whereas ambulatory blood pressure changed mainly in the first 6 months of treatment. LVMI decreased in both treatment groups, with a significantly higher reduction in lisinopril-treated subjects. Left ventricular diastolic function showed no significant changes in either group. The vascular pathophysiologic alterations of ISH-a decreased aortic distensibility-can be improved with long-term lisinopril treatment, whereas values deteriorate further in placebo-treated subjects. These results, in one of the first studies including subjects with previously untreated ISH only, indicate that lisinopril treatment might favorably influence the cardiovascular risk of ISH." @default.
• W2059314248 created "2016-06-24" @default.
• W2059314248 creator A5005628011 @default.
• W2059314248 creator A5007242268 @default.
• W2059314248 creator A5011519571 @default.
• W2059314248 creator A5014271827 @default.
• W2059314248 creator A5016321859 @default.
• W2059314248 creator A5050791063 @default.
• W2059314248 creator A5051384278 @default.
• W2059314248 creator A5057513309 @default.
• W2059314248 creator A5070352381 @default.
• W2059314248 creator A5071567967 @default.
• W2059314248 creator A5082391989 @default.
• W2059314248 date "2001-05-01" @default.
• W2059314248 modified "2023-10-16" @default.
• W2059314248 title "Reversal of Pathophysiologic Changes with Long-Term Lisinopril Treatment in Isolated Systolic Hypertension" @default.
• W2059314248 cites W1581721602 @default.
• W2059314248 cites W1735740492 @default.
• W2059314248 cites W1968223444 @default.
• W2059314248 cites W1971295041 @default.
• W2059314248 cites W1983403746 @default.
• W2059314248 cites W1986716080 @default.
• W2059314248 cites W1992281996 @default.
• W2059314248 cites W1992890029 @default.
• W2059314248 cites W1995033589 @default.
• W2059314248 cites W1995357155 @default.
• W2059314248 cites W1995934832 @default.
• W2059314248 cites W2015957045 @default.
• W2059314248 cites W2018028994 @default.
• W2059314248 cites W2019722720 @default.
• W2059314248 cites W2023144853 @default.
• W2059314248 cites W2031720640 @default.
• W2059314248 cites W2033425841 @default.
• W2059314248 cites W2034177003 @default.
• W2059314248 cites W2035141912 @default.
• W2059314248 cites W2036108134 @default.
• W2059314248 cites W2038717351 @default.
• W2059314248 cites W2038719826 @default.
• W2059314248 cites W2042859759 @default.
• W2059314248 cites W2045830832 @default.
• W2059314248 cites W2051688382 @default.
• W2059314248 cites W2054496115 @default.
• W2059314248 cites W2076737762 @default.
• W2059314248 cites W2082246284 @default.
• W2059314248 cites W2084550660 @default.
• W2059314248 cites W2088267727 @default.
• W2059314248 cites W2089635811 @default.
• W2059314248 cites W2097595842 @default.
• W2059314248 cites W2101358492 @default.
• W2059314248 cites W2106124062 @default.
• W2059314248 cites W2114634962 @default.
• W2059314248 cites W2140545439 @default.
• W2059314248 cites W2142122766 @default.
• W2059314248 cites W2146361403 @default.
• W2059314248 cites W2160986287 @default.
• W2059314248 cites W2169160940 @default.
• W2059314248 cites W2169982013 @default.
• W2059314248 cites W2222608241 @default.
• W2059314248 cites W2309064345 @default.
• W2059314248 cites W2327773932 @default.
• W2059314248 cites W2334499091 @default.
• W2059314248 cites W4232706911 @default.
• W2059314248 cites W4236124719 @default.
• W2059314248 cites W4236421691 @default.
• W2059314248 cites W4238900290 @default.
• W2059314248 cites W4253293696 @default.
• W2059314248 cites W4255713436 @default.
• W2059314248 cites W4298443613 @default.
• W2059314248 doi "https://doi.org/10.1097/00005344-200105000-00003" @default.
• W2059314248 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11336102" @default.
• W2059314248 hasPublicationYear "2001" @default.
• W2059314248 type Work @default.
• W2059314248 sameAs 2059314248 @default.
• W2059314248 citedByCount "19" @default.
• W2059314248 countsByYear W20593142482012 @default.
• W2059314248 countsByYear W20593142482013 @default.
• W2059314248 countsByYear W20593142482014 @default.
• W2059314248 countsByYear W20593142482018 @default.
• W2059314248 countsByYear W20593142482019 @default.
• W2059314248 countsByYear W20593142482020 @default.
• W2059314248 countsByYear W20593142482023 @default.
• W2059314248 crossrefType "journal-article" @default.
• W2059314248 hasAuthorship W2059314248A5005628011 @default.
• W2059314248 hasAuthorship W2059314248A5007242268 @default.
• W2059314248 hasAuthorship W2059314248A5011519571 @default.
• W2059314248 hasAuthorship W2059314248A5014271827 @default.
• W2059314248 hasAuthorship W2059314248A5016321859 @default.
• W2059314248 hasAuthorship W2059314248A5050791063 @default.
• W2059314248 hasAuthorship W2059314248A5051384278 @default.
• W2059314248 hasAuthorship W2059314248A5057513309 @default.
• W2059314248 hasAuthorship W2059314248A5070352381 @default.
• W2059314248 hasAuthorship W2059314248A5071567967 @default.
• W2059314248 hasAuthorship W2059314248A5082391989 @default.
• W2059314248 hasConcept C126322002 @default.
• W2059314248 hasConcept C142724271 @default.
• W2059314248 hasConcept C149323552 @default.
• W2059314248 hasConcept C164705383 @default.
• W2059314248 hasConcept C204787440 @default.

• next