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- W2059314934 abstract "Abstract This work evaluates the effect of carbon nanotube (CNT) addition to plasma‐sprayed hydroxyapatite (HA) coating on its tribological behavior, biocompatibility of the coating, and cytotoxicity of CNT‐containing wear debris. Biological response of the CNT‐containing wear debris is critical for osteoblasts, the bone‐forming cells, and macrophages, the cells that clear up wear debris from blood stream. The addition of 4 wt % CNTs to HA coating reduces the volume of wear debris generation by 80% because of the improved elastic modulus and fracture toughness. CNT reinforcement has a pronounced effect on the particle size in the wear debris and subsequent biological response. There was a slight increase in the numbers and viability of osteoblasts grown on HA–CNT compared with HA alone. The cytotoxic effect of HA and HA–CNT debris to macrophages and osteoblasts was similar, demonstrating that loose CNT does not pose a problem to these cells. © 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part A, 2010." @default.
- W2059314934 created "2016-06-24" @default.
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- W2059314934 date "2010-10-13" @default.
- W2059314934 modified "2023-10-10" @default.
- W2059314934 title "Wear behavior and in vitro cytotoxicity of wear debris generated from hydroxyapatite-carbon nanotube composite coating" @default.
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- W2059314934 doi "https://doi.org/10.1002/jbm.a.32952" @default.
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