Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059320845> ?p ?o ?g. }
- W2059320845 endingPage "147" @default.
- W2059320845 startingPage "139" @default.
- W2059320845 abstract "Panic disorder is characterized by spontaneous and recurrent panic attacks, often accompanied by agoraphobia. The results of family, twin, and segregation studies suggest a genetic role in the etiology of the illness. We have genotyped up to 23 families that have a high density of panic disorder with 540 microsatellite DNA markers in a first-pass genomic screen. The thirteen best families (ELOD > 6.0 under the dominant genetic model) have been genotyped with an ordered set of markers encompassing all the autosomes, at an average marker density of 11 cM. Over 110,000 genotypes have been generated on the whole set of families, and the data have been analyzed under both a dominant and a recessive model, and with the program SIBPAIR. No lod scores exceed 2.0 for either parametric model. Two markers give lod scores over 1.0 under the dominant model (chromosomes 1p and 20p), and four do under the recessive model (7p, 17p, 20q, and X/Y). One of these (20p) may be particularly promising. Analysis with SIBPAIR yielded P values equivalent to a lod score of 1.0 or greater (i.e., P < .016, one-sided, uncorrected for multiple tests) for 11 marker loci (2, 7p, 8p, 8q, 9p, 11q, 12q, 16p, 20p and 20q). Am. J. Med. Genet. (Neuropsychiatr. Genet.) 81:139–147, 1998. © 1998 Wiley-Liss, Inc." @default.
- W2059320845 created "2016-06-24" @default.
- W2059320845 creator A5002851125 @default.
- W2059320845 creator A5007970056 @default.
- W2059320845 creator A5011817917 @default.
- W2059320845 creator A5018262839 @default.
- W2059320845 creator A5018936162 @default.
- W2059320845 creator A5025278422 @default.
- W2059320845 creator A5032141778 @default.
- W2059320845 creator A5032997650 @default.
- W2059320845 creator A5033788029 @default.
- W2059320845 creator A5035081543 @default.
- W2059320845 creator A5052961927 @default.
- W2059320845 creator A5054408742 @default.
- W2059320845 creator A5060032203 @default.
- W2059320845 creator A5065816796 @default.
- W2059320845 creator A5067833188 @default.
- W2059320845 creator A5077506936 @default.
- W2059320845 creator A5077808713 @default.
- W2059320845 creator A5080851216 @default.
- W2059320845 creator A5080888103 @default.
- W2059320845 creator A5084125651 @default.
- W2059320845 creator A5090196905 @default.
- W2059320845 date "1998-03-28" @default.
- W2059320845 modified "2023-10-18" @default.
- W2059320845 title "Results of a genome-wide genetic screen for panic disorder" @default.
- W2059320845 cites W126659096 @default.
- W2059320845 cites W1278569434 @default.
- W2059320845 cites W1536326444 @default.
- W2059320845 cites W1552356868 @default.
- W2059320845 cites W1598231852 @default.
- W2059320845 cites W1953757012 @default.
- W2059320845 cites W196104318 @default.
- W2059320845 cites W1967863027 @default.
- W2059320845 cites W1976741643 @default.
- W2059320845 cites W1983126467 @default.
- W2059320845 cites W1984967391 @default.
- W2059320845 cites W1988902160 @default.
- W2059320845 cites W1989665315 @default.
- W2059320845 cites W1990337568 @default.
- W2059320845 cites W1994206731 @default.
- W2059320845 cites W1996973625 @default.
- W2059320845 cites W2019919232 @default.
- W2059320845 cites W2020478378 @default.
- W2059320845 cites W2028598043 @default.
- W2059320845 cites W2032746917 @default.
- W2059320845 cites W2033552736 @default.
- W2059320845 cites W2035085197 @default.
- W2059320845 cites W2038042393 @default.
- W2059320845 cites W2039283104 @default.
- W2059320845 cites W2040469725 @default.
- W2059320845 cites W2047052235 @default.
- W2059320845 cites W2050586615 @default.
- W2059320845 cites W2050711988 @default.
- W2059320845 cites W2052330087 @default.
- W2059320845 cites W2053707725 @default.
- W2059320845 cites W2056555981 @default.
- W2059320845 cites W2061209736 @default.
- W2059320845 cites W2061941091 @default.
- W2059320845 cites W2063199951 @default.
- W2059320845 cites W2063970228 @default.
- W2059320845 cites W2067619680 @default.
- W2059320845 cites W2070396195 @default.
- W2059320845 cites W2074922360 @default.
- W2059320845 cites W2076042086 @default.
- W2059320845 cites W2079023931 @default.
- W2059320845 cites W2079997725 @default.
- W2059320845 cites W2081422634 @default.
- W2059320845 cites W2081568209 @default.
- W2059320845 cites W2086465348 @default.
- W2059320845 cites W2086789528 @default.
- W2059320845 cites W2089416294 @default.
- W2059320845 cites W2107520338 @default.
- W2059320845 cites W2116861918 @default.
- W2059320845 cites W2125492442 @default.
- W2059320845 cites W2134899390 @default.
- W2059320845 cites W2147312951 @default.
- W2059320845 cites W2155547633 @default.
- W2059320845 cites W2163387737 @default.
- W2059320845 cites W2332142174 @default.
- W2059320845 cites W2346533325 @default.
- W2059320845 cites W2412558931 @default.
- W2059320845 cites W2412956321 @default.
- W2059320845 cites W2416119175 @default.
- W2059320845 cites W4211252102 @default.
- W2059320845 cites W53829992 @default.
- W2059320845 doi "https://doi.org/10.1002/(sici)1096-8628(19980328)81:2<139::aid-ajmg4>3.0.co;2-r" @default.
- W2059320845 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9613853" @default.
- W2059320845 hasPublicationYear "1998" @default.
- W2059320845 type Work @default.
- W2059320845 sameAs 2059320845 @default.
- W2059320845 citedByCount "128" @default.
- W2059320845 countsByYear W20593208452012 @default.
- W2059320845 countsByYear W20593208452013 @default.
- W2059320845 countsByYear W20593208452014 @default.
- W2059320845 countsByYear W20593208452018 @default.
- W2059320845 countsByYear W20593208452021 @default.
- W2059320845 crossrefType "journal-article" @default.