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- W2059378562 abstract "HLA expression is frequently altered in tumours compared to the tissue from which they originate. Given the central role of MHC products in the restriction of T-cell recognition, regulation of tumour HLA expression might be a strategy for the evasion of immune surveillance by the malignant cells. Federico Garrido, Peter Stern and colleagues present data from a variety of tumour types, suggesting that HLA class I alterations may occur at a particular step between the development of an in situ lesion and an invasive carcinoma." @default.
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- W2059378562 date "1993-10-01" @default.
- W2059378562 modified "2023-10-18" @default.
- W2059378562 title "Natural history of HLA expression during tumour development" @default.
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- W2059378562 doi "https://doi.org/10.1016/0167-5699(93)90264-l" @default.
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