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- W2059394313 abstract "The carotid sinus is a baroreceptor. The anatomy and histology of the media of the human carotid sinus, when compared with the neighbouring common and internal carotid arteries, are compatible with its having an increased distensibility. However, the sinus is the site of severe atherosclerosis which may affect its distensibility. The circumferential extensibility of the human carotid sinus has been compared with that of the common carotid artery in 30 specimens obtained at necropsy. In all except for three cases the carotid sinus was found to be less extensible than the neighbouring common carotid artery. With increasing age both arteries become less extensible. In old age and in patients with systemic hypertension the sensitivity of the baroreceptor response of the carotid sinus is diminished. Since extensibility of the sinus is impaired it is likely that the distensibility is reduced as a consequence of the severe atherosclerosis of the sinus. This may account for the diminished baroreceptor responses recorded clinically." @default.
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- W2059394313 date "1974-01-01" @default.
- W2059394313 modified "2023-09-26" @default.
- W2059394313 title "Extensibility of the human carotid sinus" @default.
- W2059394313 doi "https://doi.org/10.1093/cvr/8.1.58" @default.
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