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• W2059411701 abstract "Corticosteroids, highly effective drugs for myriad disease states, have considerable neuropsychiatric adverse effects that can manifest in cognitive disorders, behavioral changes, and frank psychiatric disease. Recent reviews have summarized these effects in adults, but a comprehensive review on corticosteroid effects in children has not been published since 2005. Here, we systematically review articles published since then that, we find, naturally divide into 3 main areas: (1) chronic effects of acute prenatal and neonatal exposure associated with prematurity and congenital conditions; (2) immediate behavioral effects of acute exposure via oncological protocols; and (3) acute behavioral effects of sporadic use in children and adolescents with other conditions. PsycInfo, MEDLINE, Embase, and Scopus were queried to identify articles reporting psychiatric adverse effects of corticosteroids in pediatric patients. Search terms included corticosteroids, adrenal cortex hormones, steroid psychosis, substance-induced psychoses, glucocorticoids, dexamethasone, hydrocortisone, prednisone, adverse effects, mood disorders, mental disorders, psychosis, psychotic, psychoses, side effect, chemically induced, emotions, affective symptoms, toxicity, behavior, behavioral symptoms, infant, child, adolescent, pediatric, paediatric, neonatal, children, teen, and teenager. Following guidelines for systematic reviews from the Potsdam Consultation on Meta-Analysis, we have found it difficult to draw specific conclusions that are more than general impressions owing to the quality of the available studies. We find a mixed picture with neonates exposed to dexamethasone, with some articles reporting eventual deficits in neuropsychiatric functioning and others reporting no effect. In pediatric patients with acute lymphoblastic leukemia, corticosteroid use appears to correlate with negative psychiatric and behavioral effects. In children treated with corticosteroids for noncancer conditions, adverse effects have been observed both during treatment and after cessation, although the data from article to article are not consistent enough to establish dose relationships. By and large, inhaled corticosteroids are considered safe and free of severe neuropsychiatric effects. Although both antipsychotic medications and benzodiazepines have been used to treat corticosteroid-induced mania and psychosis, no unified management strategy has emerged. Large-scale standardized investigations are needed to clarify the psychiatric effect of corticosteroids on children in all these conditions. Meanwhile, there is general agreement that patients as well as caregivers should be warned of the potential for behavioral adverse effects when patients receive these drugs." @default.
• W2059411701 created "2016-06-24" @default.
• W2059411701 creator A5017091774 @default.
• W2059411701 creator A5074223172 @default.
• W2059411701 date "2014-06-01" @default.
• W2059411701 modified "2023-09-25" @default.
• W2059411701 title "Psychiatric Adverse Effects of Pediatric Corticosteroid Use" @default.
• W2059411701 cites W1557537923 @default.
• W2059411701 cites W1573050736 @default.
• W2059411701 cites W1971611693 @default.
• W2059411701 cites W1978868802 @default.
• W2059411701 cites W1984247088 @default.
• W2059411701 cites W1986970401 @default.
• W2059411701 cites W1987538371 @default.
• W2059411701 cites W1994992639 @default.
• W2059411701 cites W1995153678 @default.
• W2059411701 cites W2006034591 @default.
• W2059411701 cites W2010055842 @default.
• W2059411701 cites W2014561096 @default.
• W2059411701 cites W2017975444 @default.
• W2059411701 cites W2021061086 @default.
• W2059411701 cites W2021474867 @default.
• W2059411701 cites W2023388939 @default.
• W2059411701 cites W2025300870 @default.
• W2059411701 cites W2028442219 @default.
• W2059411701 cites W2030315287 @default.
• W2059411701 cites W2031288385 @default.
• W2059411701 cites W2036076427 @default.
• W2059411701 cites W2037043114 @default.
• W2059411701 cites W2038934200 @default.
• W2059411701 cites W2039128787 @default.
• W2059411701 cites W2045002632 @default.
• W2059411701 cites W2052528381 @default.
• W2059411701 cites W2054000364 @default.
• W2059411701 cites W2054927681 @default.
• W2059411701 cites W2056225700 @default.
• W2059411701 cites W2058162289 @default.
• W2059411701 cites W2058561601 @default.
• W2059411701 cites W2061116046 @default.
• W2059411701 cites W2063424775 @default.
• W2059411701 cites W2068190887 @default.
• W2059411701 cites W2072234776 @default.
• W2059411701 cites W2073401106 @default.
• W2059411701 cites W2074746693 @default.
• W2059411701 cites W2079892655 @default.
• W2059411701 cites W2084440697 @default.
• W2059411701 cites W2086455382 @default.
• W2059411701 cites W2089808957 @default.
• W2059411701 cites W2092876395 @default.
• W2059411701 cites W2098908574 @default.
• W2059411701 cites W2101217670 @default.
• W2059411701 cites W2102133161 @default.
• W2059411701 cites W2104583170 @default.
• W2059411701 cites W2111575740 @default.
• W2059411701 cites W2114107525 @default.
• W2059411701 cites W2121047111 @default.
• W2059411701 cites W2123195523 @default.
• W2059411701 cites W2123481286 @default.
• W2059411701 cites W2127791706 @default.
• W2059411701 cites W2130196514 @default.
• W2059411701 cites W2133753359 @default.
• W2059411701 cites W2136186829 @default.
• W2059411701 cites W2145203784 @default.
• W2059411701 cites W2145474695 @default.
• W2059411701 cites W2145966195 @default.
• W2059411701 cites W2146312936 @default.
• W2059411701 cites W2150710006 @default.
• W2059411701 cites W2152740574 @default.
• W2059411701 cites W2153897956 @default.
• W2059411701 cites W2165074939 @default.
• W2059411701 cites W2169959239 @default.
• W2059411701 cites W2170106900 @default.
• W2059411701 cites W2293035635 @default.
• W2059411701 cites W2317119242 @default.
• W2059411701 cites W2326267085 @default.
• W2059411701 cites W2341194388 @default.
• W2059411701 cites W2395144924 @default.
• W2059411701 cites W2398294218 @default.
• W2059411701 cites W2116356328 @default.
• W2059411701 doi "https://doi.org/10.1016/j.mayocp.2014.01.010" @default.
• W2059411701 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24943696" @default.
• W2059411701 hasPublicationYear "2014" @default.
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