FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059431978> ?p ?o ?g. }

• W2059431978 endingPage "343" @default.
• W2059431978 startingPage "331" @default.
• W2059431978 abstract "RNA-directed DNA methylation (RdDM) is a nuclear process in which small interfering RNAs (siRNAs) direct the cytosine methylation of DNA sequences that are complementary to the siRNAs. In plants, double stranded-RNAs (dsRNAs) generated by RNA-dependent RNA polymerase 2 (RDR2) serve as precursors for Dicer-like 3 dependent biogenesis of 24-nt siRNAs. Plant specific RNA polymerase IV (Pol IV) is presumed to generate the initial RNA transcripts that are substrates for RDR2. siRNAs are loaded onto an argonaute4-containing RISC (RNA-induced silencing complex) that targets the de novo DNA methyltransferase DRM2 to RdDM target loci. Nascent RNA transcripts from the target loci are generated by another plant-specific RNA polymerase, Pol V, and these transcripts help recruit complementary siRNAs and the associated RdDM effector complex to the target loci in a transcription-coupled DNA methylation process. Small RNA binding proteins such as ROS3 may direct target-specific DNA demethylation by the ROS1 family of DNA demethylases. Chromatin remodeling enzymes and histone modifying enzymes also participate in DNA methylation and possibly demethylation. One of the well studied functions of RdDM is transposon silencing and genome stability. In addition, RdDM is important for paramutation, imprinting, gene regulation, and plant development. Locus-specific DNA methylation and demethylation, and transposon activation under abiotic stresses suggest that RdDM is also important in stress responses of plants. Further studies will help illuminate the functions of RdDM in the dynamic control of epigenomes during development and environmental stress responses." @default.
• W2059431978 created "2016-06-24" @default.
• W2059431978 creator A5004149609 @default.
• W2059431978 creator A5037996538 @default.
• W2059431978 date "2009-04-01" @default.
• W2059431978 modified "2023-09-26" @default.
• W2059431978 title "RNA-directed DNA methylation and demethylation in plants" @default.
• W2059431978 cites W1550720320 @default.
• W2059431978 cites W1964197670 @default.
• W2059431978 cites W1964271596 @default.
• W2059431978 cites W1964388814 @default.
• W2059431978 cites W1965851786 @default.
• W2059431978 cites W1967655525 @default.
• W2059431978 cites W1971700852 @default.
• W2059431978 cites W1972245150 @default.
• W2059431978 cites W1973036268 @default.
• W2059431978 cites W1973640585 @default.
• W2059431978 cites W1976799634 @default.
• W2059431978 cites W1979154939 @default.
• W2059431978 cites W1985658587 @default.
• W2059431978 cites W1986328541 @default.
• W2059431978 cites W1989067040 @default.
• W2059431978 cites W1989568035 @default.
• W2059431978 cites W1999989168 @default.
• W2059431978 cites W2001448730 @default.
• W2059431978 cites W2001476164 @default.
• W2059431978 cites W2002377333 @default.
• W2059431978 cites W2004612536 @default.
• W2059431978 cites W2007250559 @default.
• W2059431978 cites W2008268168 @default.
• W2059431978 cites W2008787483 @default.
• W2059431978 cites W2012865420 @default.
• W2059431978 cites W2013033579 @default.
• W2059431978 cites W2015523315 @default.
• W2059431978 cites W2019471731 @default.
• W2059431978 cites W2019896138 @default.
• W2059431978 cites W2020878700 @default.
• W2059431978 cites W2021735982 @default.
• W2059431978 cites W2025025506 @default.
• W2059431978 cites W2026222098 @default.
• W2059431978 cites W2030506347 @default.
• W2059431978 cites W2031828946 @default.
• W2059431978 cites W2032798768 @default.
• W2059431978 cites W2039729902 @default.
• W2059431978 cites W2039866479 @default.
• W2059431978 cites W2041793621 @default.
• W2059431978 cites W2050507681 @default.
• W2059431978 cites W2053060513 @default.
• W2059431978 cites W2054854463 @default.
• W2059431978 cites W2056196527 @default.
• W2059431978 cites W2057162139 @default.
• W2059431978 cites W2059979506 @default.
• W2059431978 cites W2060273066 @default.
• W2059431978 cites W2064489231 @default.
• W2059431978 cites W2065194989 @default.
• W2059431978 cites W2066511342 @default.
• W2059431978 cites W2067151470 @default.
• W2059431978 cites W2070062215 @default.
• W2059431978 cites W2070062799 @default.
• W2059431978 cites W2070491119 @default.
• W2059431978 cites W2070792578 @default.
• W2059431978 cites W2071126653 @default.
• W2059431978 cites W2075639014 @default.
• W2059431978 cites W2077252766 @default.
• W2059431978 cites W2077563214 @default.
• W2059431978 cites W2079514282 @default.
• W2059431978 cites W2081162422 @default.
• W2059431978 cites W2087874602 @default.
• W2059431978 cites W2089812281 @default.
• W2059431978 cites W2091070751 @default.
• W2059431978 cites W2091993575 @default.
• W2059431978 cites W2094482988 @default.
• W2059431978 cites W2094861513 @default.
• W2059431978 cites W2100771714 @default.
• W2059431978 cites W2100999894 @default.
• W2059431978 cites W2101814858 @default.
• W2059431978 cites W2103444581 @default.
• W2059431978 cites W2107337799 @default.
• W2059431978 cites W2108031268 @default.
• W2059431978 cites W2109458502 @default.
• W2059431978 cites W2110289886 @default.
• W2059431978 cites W2110416200 @default.
• W2059431978 cites W2111401971 @default.
• W2059431978 cites W2119283450 @default.
• W2059431978 cites W2121304801 @default.
• W2059431978 cites W2122711136 @default.
• W2059431978 cites W2125451800 @default.
• W2059431978 cites W2125893498 @default.
• W2059431978 cites W2126459055 @default.
• W2059431978 cites W2126606466 @default.
• W2059431978 cites W2128874237 @default.
• W2059431978 cites W2135851907 @default.
• W2059431978 cites W2137483650 @default.
• W2059431978 cites W2139288600 @default.
• W2059431978 cites W2139712782 @default.
• W2059431978 cites W2141116637 @default.
• W2059431978 cites W2142338990 @default.
• W2059431978 cites W2143161993 @default.

• next