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- W2059441680 abstract "While the treponemicidal properties of erythromycin were first described in 1953 by Keller and Morton,<sup>1</sup>it is only recently that adequate clinical information has become available. Keller and Morton, as well as Turner and Schaeffer,<sup>2</sup>were able to demonstrate Treponema pallidum more susceptible to the action of erythromycin than other antibiotics with the exception of penicillin. Later, Kolmer<sup>3</sup>reported similar treponemicidal properties to erythromycin but obtained superior results with several other antibiotics. In 1954 Alexander and Schoch<sup>4</sup>treated 4 patients with syphilitic lesions with erythromycin and observed rapid disappearance of Treponema pallidum from the lesions. In 1956 Montero<sup>5</sup>presented 27 patients with early syphilis treated with a total of 9 to 12 gm. of erythromycin with satisfactory results. In 1959 Montgomery and Knox<sup>6</sup>reported on 40 darkfield-positive cases of early syphilis treated with 9 to 10 gm. of erythromycin stearate over a period of" @default.
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- W2059441680 date "1961-05-01" @default.
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- W2059441680 title "Erythromycin in Treatment of Early Syphilis" @default.
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- W2059441680 doi "https://doi.org/10.1001/archinte.1961.03620050098010" @default.
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