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- W2059457789 abstract "Plexiform neurofibroma is a relatively common but potentially devastating manifestation of neurofibromatosis type 1 (NF1). Surgical management is the mainstay of therapy, but within the head and neck region it is limited by the infiltrating nature of these tumors, inherent operative morbidity, and high rate of regrowth.We describe a case of a 7-year-old girl with neurofibromatosis type 1 and a massive facial plexiform neurofibroma with the aim of emphasizing the treatment and timing issues involved in the management of this difficult problem. A MEDLINE search (1966 through December 2000) was carried out, and pertinent literature on the subject was reviewed.The patient described in this case report was carefully observed for a period of 6 years from diagnosis before surgical excision of the tumor was undertaken with an uneventful recovery.Surgical management remains the mainstay of treatment for these locally invasive tumors, but functional disturbances are almost inevitable in resecting substantial tumors involving the head and neck region. The indication and timing of surgery in pediatric patients therefore needs to be carefully weighed against the physical and psychologic consequences of treatment." @default.
- W2059457789 created "2016-06-24" @default.
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- W2059457789 date "2002-01-02" @default.
- W2059457789 modified "2023-09-26" @default.
- W2059457789 title "Management issues in massive pediatric facial plexiform neurofibroma with neurofibromatosis type 1" @default.
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- W2059457789 doi "https://doi.org/10.1002/hed.10001" @default.
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