Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059492046> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2059492046 endingPage "253" @default.
- W2059492046 startingPage "245" @default.
- W2059492046 abstract "A sensitive LC-MS quantitation method of cetrorelix, a novel gonadotropin releasing hormone (GnRH) antagonist, was developed. Plasma and urine samples to which brominated cetrorelix was added as an internal standard (I.S.) were purified by solid-phase extraction with C8 cartridges. The chromatographic separation was achieved on a C18 reversed-phase column using acetonitrile-water-trifluoroacetic acid (35:65:0.1, v/v/v) as mobile phase. The mass spectrometric analysis was performed by electrospray ionization mode with negative ion detection, and the adduct ions of cetrorelix and I.S. with trifluoroacetic acid were monitored in extremely high mass region of m/z 1543 and 1700, respectively. The lower limit of quantitation was 1.00 ng per 1 ml of plasma and 2.09 ng per 2 ml of urine, and the present method was applied to the analysis of pharmacokinetics of cetrorelix in human during phase 1 clinical trial." @default.
- W2059492046 created "2016-06-24" @default.
- W2059492046 creator A5003064051 @default.
- W2059492046 creator A5004120208 @default.
- W2059492046 creator A5082920391 @default.
- W2059492046 date "1999-06-01" @default.
- W2059492046 modified "2023-10-14" @default.
- W2059492046 title "Measurement of the novel decapeptide cetrorelix in human plasma and urine by liquid chromatography–electrospray ionization mass spectrometry" @default.
- W2059492046 cites W1536596442 @default.
- W2059492046 cites W1980977527 @default.
- W2059492046 cites W1984475099 @default.
- W2059492046 cites W2006998103 @default.
- W2059492046 cites W2018053441 @default.
- W2059492046 cites W2038243639 @default.
- W2059492046 doi "https://doi.org/10.1016/s0378-4347(99)00168-1" @default.
- W2059492046 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10410949" @default.
- W2059492046 hasPublicationYear "1999" @default.
- W2059492046 type Work @default.
- W2059492046 sameAs 2059492046 @default.
- W2059492046 citedByCount "30" @default.
- W2059492046 countsByYear W20594920462013 @default.
- W2059492046 countsByYear W20594920462014 @default.
- W2059492046 countsByYear W20594920462015 @default.
- W2059492046 countsByYear W20594920462017 @default.
- W2059492046 countsByYear W20594920462019 @default.
- W2059492046 countsByYear W20594920462020 @default.
- W2059492046 crossrefType "journal-article" @default.
- W2059492046 hasAuthorship W2059492046A5003064051 @default.
- W2059492046 hasAuthorship W2059492046A5004120208 @default.
- W2059492046 hasAuthorship W2059492046A5082920391 @default.
- W2059492046 hasConcept C119128265 @default.
- W2059492046 hasConcept C162356407 @default.
- W2059492046 hasConcept C185592680 @default.
- W2059492046 hasConcept C2777463227 @default.
- W2059492046 hasConcept C2780026642 @default.
- W2059492046 hasConcept C2780112151 @default.
- W2059492046 hasConcept C40684141 @default.
- W2059492046 hasConcept C43617362 @default.
- W2059492046 hasConcept C4725764 @default.
- W2059492046 hasConcept C55493867 @default.
- W2059492046 hasConcept C81426234 @default.
- W2059492046 hasConceptScore W2059492046C119128265 @default.
- W2059492046 hasConceptScore W2059492046C162356407 @default.
- W2059492046 hasConceptScore W2059492046C185592680 @default.
- W2059492046 hasConceptScore W2059492046C2777463227 @default.
- W2059492046 hasConceptScore W2059492046C2780026642 @default.
- W2059492046 hasConceptScore W2059492046C2780112151 @default.
- W2059492046 hasConceptScore W2059492046C40684141 @default.
- W2059492046 hasConceptScore W2059492046C43617362 @default.
- W2059492046 hasConceptScore W2059492046C4725764 @default.
- W2059492046 hasConceptScore W2059492046C55493867 @default.
- W2059492046 hasConceptScore W2059492046C81426234 @default.
- W2059492046 hasIssue "1-2" @default.
- W2059492046 hasLocation W20594920461 @default.
- W2059492046 hasLocation W20594920462 @default.
- W2059492046 hasOpenAccess W2059492046 @default.
- W2059492046 hasPrimaryLocation W20594920461 @default.
- W2059492046 hasRelatedWork W1883337067 @default.
- W2059492046 hasRelatedWork W1985832542 @default.
- W2059492046 hasRelatedWork W1992386112 @default.
- W2059492046 hasRelatedWork W2032892660 @default.
- W2059492046 hasRelatedWork W2035929101 @default.
- W2059492046 hasRelatedWork W2067441895 @default.
- W2059492046 hasRelatedWork W2109347368 @default.
- W2059492046 hasRelatedWork W2116968750 @default.
- W2059492046 hasRelatedWork W2355727266 @default.
- W2059492046 hasRelatedWork W2412453102 @default.
- W2059492046 hasVolume "729" @default.
- W2059492046 isParatext "false" @default.
- W2059492046 isRetracted "false" @default.
- W2059492046 magId "2059492046" @default.
- W2059492046 workType "article" @default.