Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059505715> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2059505715 endingPage "575" @default.
- W2059505715 startingPage "571" @default.
- W2059505715 abstract "To avoid the side effects of systemic administration of ganciclovir (GCV) for the treatment of cytomegalovirus (CMV) retinitis, we studied transscleral iontophoresis of GCV into rabbit eyes. After a single application with 20% (w/w) aqueous solution of GCV at 1.0 mA for 15 min gave a vitreal/retinal level of GCV at 74±17 ug/ml at 2 hours as determined by HPLC. At 24 hours after iontophoresis the vitreal/retinal level was above therapeutic level at 4.2±0.6 ug/ml. At 72 hours, there was still detectable level in the vitreous/retina. Hence, transscleral iontophoresis is able to deliver effective dose of GCV into the vitreous. Multiple applications of iontophoresis should be examined as a possible means of CMV treatment." @default.
- W2059505715 created "2016-06-24" @default.
- W2059505715 creator A5034692540 @default.
- W2059505715 creator A5043470840 @default.
- W2059505715 creator A5051209547 @default.
- W2059505715 creator A5082578606 @default.
- W2059505715 creator A5084560281 @default.
- W2059505715 creator A5088990610 @default.
- W2059505715 date "1994-01-01" @default.
- W2059505715 modified "2023-10-07" @default.
- W2059505715 title "Intravitreal Delivery of Ganciclovir in Rabbits by Transscleral Iontophoresis" @default.
- W2059505715 cites W1968995676 @default.
- W2059505715 cites W1970094487 @default.
- W2059505715 cites W1977296274 @default.
- W2059505715 cites W1982079405 @default.
- W2059505715 cites W2015911929 @default.
- W2059505715 cites W2036942072 @default.
- W2059505715 cites W2047621907 @default.
- W2059505715 cites W2060467997 @default.
- W2059505715 cites W2075740239 @default.
- W2059505715 cites W2092088395 @default.
- W2059505715 cites W2094176836 @default.
- W2059505715 cites W2122064095 @default.
- W2059505715 cites W2164265529 @default.
- W2059505715 cites W2616647315 @default.
- W2059505715 cites W4242511899 @default.
- W2059505715 doi "https://doi.org/10.1089/jop.1994.10.571" @default.
- W2059505715 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7836866" @default.
- W2059505715 hasPublicationYear "1994" @default.
- W2059505715 type Work @default.
- W2059505715 sameAs 2059505715 @default.
- W2059505715 citedByCount "29" @default.
- W2059505715 countsByYear W20595057152013 @default.
- W2059505715 countsByYear W20595057152014 @default.
- W2059505715 countsByYear W20595057152016 @default.
- W2059505715 countsByYear W20595057152018 @default.
- W2059505715 countsByYear W20595057152020 @default.
- W2059505715 countsByYear W20595057152023 @default.
- W2059505715 crossrefType "journal-article" @default.
- W2059505715 hasAuthorship W2059505715A5034692540 @default.
- W2059505715 hasAuthorship W2059505715A5043470840 @default.
- W2059505715 hasAuthorship W2059505715A5051209547 @default.
- W2059505715 hasAuthorship W2059505715A5082578606 @default.
- W2059505715 hasAuthorship W2059505715A5084560281 @default.
- W2059505715 hasAuthorship W2059505715A5088990610 @default.
- W2059505715 hasConcept C118487528 @default.
- W2059505715 hasConcept C126838900 @default.
- W2059505715 hasConcept C159047783 @default.
- W2059505715 hasConcept C183529106 @default.
- W2059505715 hasConcept C2522874641 @default.
- W2059505715 hasConcept C2777324356 @default.
- W2059505715 hasConcept C2777965375 @default.
- W2059505715 hasConcept C2779820661 @default.
- W2059505715 hasConcept C2780827179 @default.
- W2059505715 hasConcept C2993390227 @default.
- W2059505715 hasConcept C71924100 @default.
- W2059505715 hasConceptScore W2059505715C118487528 @default.
- W2059505715 hasConceptScore W2059505715C126838900 @default.
- W2059505715 hasConceptScore W2059505715C159047783 @default.
- W2059505715 hasConceptScore W2059505715C183529106 @default.
- W2059505715 hasConceptScore W2059505715C2522874641 @default.
- W2059505715 hasConceptScore W2059505715C2777324356 @default.
- W2059505715 hasConceptScore W2059505715C2777965375 @default.
- W2059505715 hasConceptScore W2059505715C2779820661 @default.
- W2059505715 hasConceptScore W2059505715C2780827179 @default.
- W2059505715 hasConceptScore W2059505715C2993390227 @default.
- W2059505715 hasConceptScore W2059505715C71924100 @default.
- W2059505715 hasIssue "3" @default.
- W2059505715 hasLocation W20595057151 @default.
- W2059505715 hasLocation W20595057152 @default.
- W2059505715 hasOpenAccess W2059505715 @default.
- W2059505715 hasPrimaryLocation W20595057151 @default.
- W2059505715 hasRelatedWork W1480343078 @default.
- W2059505715 hasRelatedWork W1963787791 @default.
- W2059505715 hasRelatedWork W2048423009 @default.
- W2059505715 hasRelatedWork W2059505715 @default.
- W2059505715 hasRelatedWork W2073011200 @default.
- W2059505715 hasRelatedWork W2461807753 @default.
- W2059505715 hasRelatedWork W3116555047 @default.
- W2059505715 hasRelatedWork W4224443295 @default.
- W2059505715 hasRelatedWork W778113423 @default.
- W2059505715 hasRelatedWork W1993716530 @default.
- W2059505715 hasVolume "10" @default.
- W2059505715 isParatext "false" @default.
- W2059505715 isRetracted "false" @default.
- W2059505715 magId "2059505715" @default.
- W2059505715 workType "article" @default.