Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059557958> ?p ?o ?g. }
- W2059557958 endingPage "52" @default.
- W2059557958 startingPage "43" @default.
- W2059557958 abstract "We describe the specific silencing of reporter gene lacZ in FHM cells (muscle cells of fathead minnow, a fish cell line) by either expressing small hairpin RNAs (shRNAs) from plasmids or transfecting small interfering RNAs (siRNAs) transcribed in vitro. Two types of dsRNAs could inhibit reporter gene expression, and siRNAs were more effective, while both of them worked very well in HeLa cells. siRNAs were tested for silencing expression of the major capsid protein (MCP) encoded by tiger frog virus (TFV), an iridovirus causing severe disease in fish. siRNAs targeting mcp gene effectively inhibited TFV replication in fish cells as demonstrated by reduced mcp RNA level, postponed emergence of cytopathogenic effect, as well as reduced TFV titer and particles in cells. The results suggest that the siRNA method suppressed TFV efficiently in fish cells, providing a potential approach to the therapy of aquaculture viral diseases." @default.
- W2059557958 created "2016-06-24" @default.
- W2059557958 creator A5016563317 @default.
- W2059557958 creator A5020471386 @default.
- W2059557958 creator A5022895653 @default.
- W2059557958 creator A5026449732 @default.
- W2059557958 creator A5028424745 @default.
- W2059557958 creator A5036767353 @default.
- W2059557958 creator A5048436440 @default.
- W2059557958 creator A5054351096 @default.
- W2059557958 date "2005-07-01" @default.
- W2059557958 modified "2023-10-01" @default.
- W2059557958 title "Inhibition of reporter gene and Iridovirus-tiger frog virus in fish cell by RNA interference" @default.
- W2059557958 cites W1488192195 @default.
- W2059557958 cites W1548528591 @default.
- W2059557958 cites W1611419331 @default.
- W2059557958 cites W1647075334 @default.
- W2059557958 cites W18101382 @default.
- W2059557958 cites W1967248009 @default.
- W2059557958 cites W1967418748 @default.
- W2059557958 cites W1987130889 @default.
- W2059557958 cites W1988529503 @default.
- W2059557958 cites W1991902309 @default.
- W2059557958 cites W1995768712 @default.
- W2059557958 cites W2009469417 @default.
- W2059557958 cites W2015664969 @default.
- W2059557958 cites W2019678529 @default.
- W2059557958 cites W2021617407 @default.
- W2059557958 cites W2023447954 @default.
- W2059557958 cites W2026123650 @default.
- W2059557958 cites W2028429209 @default.
- W2059557958 cites W2029653860 @default.
- W2059557958 cites W2029896450 @default.
- W2059557958 cites W2036008887 @default.
- W2059557958 cites W2039094859 @default.
- W2059557958 cites W2047010595 @default.
- W2059557958 cites W2048477888 @default.
- W2059557958 cites W2064281959 @default.
- W2059557958 cites W2073002742 @default.
- W2059557958 cites W2084619527 @default.
- W2059557958 cites W2084851425 @default.
- W2059557958 cites W2107235611 @default.
- W2059557958 cites W2114406978 @default.
- W2059557958 cites W2116973451 @default.
- W2059557958 cites W2126357434 @default.
- W2059557958 cites W2128363166 @default.
- W2059557958 cites W2137278881 @default.
- W2059557958 cites W2147789775 @default.
- W2059557958 cites W2153747430 @default.
- W2059557958 cites W2161074631 @default.
- W2059557958 cites W2161208250 @default.
- W2059557958 cites W2161617747 @default.
- W2059557958 cites W2163576959 @default.
- W2059557958 cites W2163863526 @default.
- W2059557958 cites W2321937822 @default.
- W2059557958 cites W2328897088 @default.
- W2059557958 cites W2330774094 @default.
- W2059557958 cites W4211148978 @default.
- W2059557958 cites W4254038279 @default.
- W2059557958 doi "https://doi.org/10.1016/j.virol.2005.04.040" @default.
- W2059557958 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15932766" @default.
- W2059557958 hasPublicationYear "2005" @default.
- W2059557958 type Work @default.
- W2059557958 sameAs 2059557958 @default.
- W2059557958 citedByCount "52" @default.
- W2059557958 countsByYear W20595579582012 @default.
- W2059557958 countsByYear W20595579582013 @default.
- W2059557958 countsByYear W20595579582014 @default.
- W2059557958 countsByYear W20595579582015 @default.
- W2059557958 countsByYear W20595579582016 @default.
- W2059557958 countsByYear W20595579582017 @default.
- W2059557958 countsByYear W20595579582018 @default.
- W2059557958 countsByYear W20595579582019 @default.
- W2059557958 countsByYear W20595579582020 @default.
- W2059557958 countsByYear W20595579582022 @default.
- W2059557958 countsByYear W20595579582023 @default.
- W2059557958 crossrefType "journal-article" @default.
- W2059557958 hasAuthorship W2059557958A5016563317 @default.
- W2059557958 hasAuthorship W2059557958A5020471386 @default.
- W2059557958 hasAuthorship W2059557958A5022895653 @default.
- W2059557958 hasAuthorship W2059557958A5026449732 @default.
- W2059557958 hasAuthorship W2059557958A5028424745 @default.
- W2059557958 hasAuthorship W2059557958A5036767353 @default.
- W2059557958 hasAuthorship W2059557958A5048436440 @default.
- W2059557958 hasAuthorship W2059557958A5054351096 @default.
- W2059557958 hasConcept C104317684 @default.
- W2059557958 hasConcept C119056186 @default.
- W2059557958 hasConcept C150194340 @default.
- W2059557958 hasConcept C153911025 @default.
- W2059557958 hasConcept C159047783 @default.
- W2059557958 hasConcept C161733203 @default.
- W2059557958 hasConcept C166703698 @default.
- W2059557958 hasConcept C2191507 @default.
- W2059557958 hasConcept C22615655 @default.
- W2059557958 hasConcept C2522874641 @default.
- W2059557958 hasConcept C2909396630 @default.
- W2059557958 hasConcept C54009773 @default.
- W2059557958 hasConcept C54355233 @default.