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- W2059586239 abstract "The yeast Saccharomyces cerevisiae was tested as a recipient for functional expression of a mammalian lysosomal enzyme. The β chain of human β-hexosaminidase formed active dimeric enzyme, HexB, in transformants. HexB activity was localized to the vacuole, the yeast counterpart to the lysosome. A simple in situ enzyme assay was developed, which could be useful in expressing other lysosomal cDNAs." @default.
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- W2059586239 date "1990-07-01" @default.
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- W2059586239 title "Expression of human lysosomal β-hexosaminidase in yeast vacuoles" @default.
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- W2059586239 doi "https://doi.org/10.1016/0006-291x(90)91285-z" @default.
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