FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059601864> ?p ?o ?g. }

• W2059601864 endingPage "698" @default.
• W2059601864 startingPage "691" @default.
• W2059601864 abstract "Abstract— Cryoplates were implanted on the surface of the cortex in 32 chronic rat preparations. These devices were used both to freeze and to extract small samples of tissue. Coolant was circulated through each device by small flexible polyethylene tubes. Two series of experiments were performed. In the first, the animals were unrestrained and showed no behavioral signs of stress during the freeze fixation. The temperature responses of the cryoplates were very rapid (−632°C/s), and samples more than 1 mm thick were frozen and extracted within a few hundred ms following the onset of cooling. Each sample was analyzed for 3′.5′-adenosine monophosphate (cyclic AMP) and protein content. The results from the cryoplate group (25.6 ± 15.6pmol cyclic AMP/mg protein) were compared to those obtained from two other groups in which freeze fixation was produced by immersion in liquid nitrogen (13.6 ± 4.6pmol/mg protein) or decapitation into liquid nitrogen (18.6 + 7.6pmol/mg protein). In the second series of experiments, three types of stress (limb restraint, non-adaptation to the experimental situation, and moderate cutaneous electric shock) were induced separately in order to determine the influence of each on cortical levels of cyclic AMP. Control animals were highly adapted to the experimental situation, freely moving and not shocked. The samples from each of the stressed groups showed a statistically significant (P≤. 0.01) reduction in cyclic AMP in comparison with the level in the controls (control: 29.3 pmol/mg protein; restrained: 14.2pmol/mg protein; unadapted: 9.6pmol/mg protein; shocked: 7.1 pmol/mg protein). Thus, psychological and physical stress reduced cyclic AMP content in parietal cortex. Results from the second series of experiments suggest that the significantly higher mean and larger standard deviation of the cryoplate group in the first series are due to less psychological and physical stress being evoked by our method; different types of stress appear to account for the two different lower levels found in the immersion and decapitation groups. We believe that our method of cryogenic tissue fixation offers an improved approach to study of the neurochemical correlates of behavioral and neuroelectric events in the conscious animal." @default.
• W2059601864 created "2016-06-24" @default.
• W2059601864 creator A5006397020 @default.
• W2059601864 creator A5009616322 @default.
• W2059601864 creator A5034245099 @default.
• W2059601864 creator A5056575315 @default.
• W2059601864 date "1978-04-01" @default.
• W2059601864 modified "2023-09-26" @default.
• W2059601864 title "PSYCHOLOGICAL STRESS REDUCES CYCLIC 3',5'-ADENOSINE MONOPHOSPHATE LEVELS IN THE CEREBRAL CORTEX OF CONSCIOUS RATS, AS DETERMINED BY A NEW CRYOGENIC METHOD OF RAPID TISSUE FIXATION" @default.
• W2059601864 cites W1984630740 @default.
• W2059601864 cites W1996466550 @default.
• W2059601864 cites W2022038613 @default.
• W2059601864 cites W2043263849 @default.
• W2059601864 cites W3025622176 @default.
• W2059601864 cites W45574617 @default.
• W2059601864 doi "https://doi.org/10.1111/j.1471-4159.1978.tb10773.x" @default.
• W2059601864 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/206665" @default.
• W2059601864 hasPublicationYear "1978" @default.
• W2059601864 type Work @default.
• W2059601864 sameAs 2059601864 @default.
• W2059601864 citedByCount "25" @default.
• W2059601864 countsByYear W20596018642014 @default.
• W2059601864 countsByYear W20596018642015 @default.
• W2059601864 crossrefType "journal-article" @default.
• W2059601864 hasAuthorship W2059601864A5006397020 @default.
• W2059601864 hasAuthorship W2059601864A5009616322 @default.
• W2059601864 hasAuthorship W2059601864A5034245099 @default.
• W2059601864 hasAuthorship W2059601864A5056575315 @default.
• W2059601864 hasConcept C104317684 @default.
• W2059601864 hasConcept C108939769 @default.
• W2059601864 hasConcept C126322002 @default.
• W2059601864 hasConcept C134018914 @default.
• W2059601864 hasConcept C146249460 @default.
• W2059601864 hasConcept C170493617 @default.
• W2059601864 hasConcept C178790620 @default.
• W2059601864 hasConcept C185592680 @default.
• W2059601864 hasConcept C2776668983 @default.
• W2059601864 hasConcept C2776991684 @default.
• W2059601864 hasConcept C2781041448 @default.
• W2059601864 hasConcept C43617362 @default.
• W2059601864 hasConcept C55493867 @default.
• W2059601864 hasConcept C71924100 @default.
• W2059601864 hasConcept C86803240 @default.
• W2059601864 hasConceptScore W2059601864C104317684 @default.
• W2059601864 hasConceptScore W2059601864C108939769 @default.
• W2059601864 hasConceptScore W2059601864C126322002 @default.
• W2059601864 hasConceptScore W2059601864C134018914 @default.
• W2059601864 hasConceptScore W2059601864C146249460 @default.
• W2059601864 hasConceptScore W2059601864C170493617 @default.
• W2059601864 hasConceptScore W2059601864C178790620 @default.
• W2059601864 hasConceptScore W2059601864C185592680 @default.
• W2059601864 hasConceptScore W2059601864C2776668983 @default.
• W2059601864 hasConceptScore W2059601864C2776991684 @default.
• W2059601864 hasConceptScore W2059601864C2781041448 @default.
• W2059601864 hasConceptScore W2059601864C43617362 @default.
• W2059601864 hasConceptScore W2059601864C55493867 @default.
• W2059601864 hasConceptScore W2059601864C71924100 @default.
• W2059601864 hasConceptScore W2059601864C86803240 @default.
• W2059601864 hasIssue "4" @default.
• W2059601864 hasLocation W20596018641 @default.
• W2059601864 hasLocation W20596018642 @default.
• W2059601864 hasOpenAccess W2059601864 @default.
• W2059601864 hasPrimaryLocation W20596018641 @default.
• W2059601864 hasRelatedWork W1965943749 @default.
• W2059601864 hasRelatedWork W1978639835 @default.
• W2059601864 hasRelatedWork W2026105695 @default.
• W2059601864 hasRelatedWork W2031470785 @default.
• W2059601864 hasRelatedWork W2045445350 @default.
• W2059601864 hasRelatedWork W2056270585 @default.
• W2059601864 hasRelatedWork W2074641809 @default.
• W2059601864 hasRelatedWork W2320914227 @default.
• W2059601864 hasRelatedWork W4236170379 @default.
• W2059601864 hasRelatedWork W4252850006 @default.
• W2059601864 hasVolume "30" @default.
• W2059601864 isParatext "false" @default.
• W2059601864 isRetracted "false" @default.
• W2059601864 magId "2059601864" @default.
• W2059601864 workType "article" @default.