FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059621062> ?p ?o ?g. }

• W2059621062 endingPage "1252" @default.
• W2059621062 startingPage "1247" @default.
• W2059621062 abstract "Plexins are the primary receptors of semaphorins, and participate in the majority of intracellular pathways triggered by semaphorins, including the regulation of cell adhesion and the motility of numerous cell types. Recently, several studies have reported that plexins can significantly affect different aspects of cancer cell biology, and the aberrant expression of plexins has been observed in a wide variety of tumor types. However, the expression and role of plexin‑B3 in hepatocellular carcinoma (HCC) is yet to be investigated. In the present study, plexin‑B3 expression was measured in 14 paired HCC samples and the corresponding adjacent non‑cancerous tissue by quantitative polymerase chain reaction and western blot analysis. The results indicated that the mRNA and protein expression levels of plexin‑B3 were downregulated in HCC samples when compared with the corresponding adjacent non‑cancerous tissue. In order to elucidate the correlation between clinicopathological data and the expression of plexin‑B3 in patients with HCC, 84 HCC archived specimens were analyzed by immunohistochemistry (IHC). The IHC results revealed that the protein expression level of plexin‑B3 was lower in the HCC samples compared with the corresponding adjacent non‑cancerous tissue, and plexin‑B3 underexpression was correlated with the patient gender and tumor size. In conclusion, these results indicated that loss of plexin‑B3 in HCC may be of predictive value for the occurrence and progression of HCC. Thus, plexin‑B3 may be a promising biomarker for the diagnosis and treatment of tumors in the future." @default.
• W2059621062 created "2016-06-24" @default.
• W2059621062 creator A5001055732 @default.
• W2059621062 creator A5007500307 @default.
• W2059621062 creator A5018863416 @default.
• W2059621062 creator A5043997883 @default.
• W2059621062 creator A5053766095 @default.
• W2059621062 creator A5060947076 @default.
• W2059621062 creator A5069813415 @default.
• W2059621062 creator A5081065929 @default.
• W2059621062 date "2015-01-30" @default.
• W2059621062 modified "2023-10-16" @default.
• W2059621062 title "Loss of plexin-B3 in hepatocellular carcinoma" @default.
• W2059621062 cites W1243134829 @default.
• W2059621062 cites W1551253202 @default.
• W2059621062 cites W1964829819 @default.
• W2059621062 cites W1968438940 @default.
• W2059621062 cites W1970761475 @default.
• W2059621062 cites W1983400501 @default.
• W2059621062 cites W1984711032 @default.
• W2059621062 cites W1987695717 @default.
• W2059621062 cites W1988288569 @default.
• W2059621062 cites W1993500032 @default.
• W2059621062 cites W1998549783 @default.
• W2059621062 cites W2000336618 @default.
• W2059621062 cites W2000762378 @default.
• W2059621062 cites W2017618441 @default.
• W2059621062 cites W2033925501 @default.
• W2059621062 cites W2035032193 @default.
• W2059621062 cites W2042551210 @default.
• W2059621062 cites W2055613750 @default.
• W2059621062 cites W2057181320 @default.
• W2059621062 cites W2062550246 @default.
• W2059621062 cites W2082970093 @default.
• W2059621062 cites W2104393011 @default.
• W2059621062 cites W2106787323 @default.
• W2059621062 cites W2140016882 @default.
• W2059621062 cites W2142920595 @default.
• W2059621062 cites W2167460551 @default.
• W2059621062 cites W370475271 @default.
• W2059621062 cites W4239180165 @default.
• W2059621062 cites W4253566969 @default.
• W2059621062 doi "https://doi.org/10.3892/etm.2015.2243" @default.
• W2059621062 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4353781" @default.
• W2059621062 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25780417" @default.
• W2059621062 hasPublicationYear "2015" @default.
• W2059621062 type Work @default.
• W2059621062 sameAs 2059621062 @default.
• W2059621062 citedByCount "9" @default.
• W2059621062 countsByYear W20596210622017 @default.
• W2059621062 countsByYear W20596210622020 @default.
• W2059621062 countsByYear W20596210622021 @default.
• W2059621062 countsByYear W20596210622022 @default.
• W2059621062 countsByYear W20596210622023 @default.
• W2059621062 crossrefType "journal-article" @default.
• W2059621062 hasAuthorship W2059621062A5001055732 @default.
• W2059621062 hasAuthorship W2059621062A5007500307 @default.
• W2059621062 hasAuthorship W2059621062A5018863416 @default.
• W2059621062 hasAuthorship W2059621062A5043997883 @default.
• W2059621062 hasAuthorship W2059621062A5053766095 @default.
• W2059621062 hasAuthorship W2059621062A5060947076 @default.
• W2059621062 hasAuthorship W2059621062A5069813415 @default.
• W2059621062 hasAuthorship W2059621062A5081065929 @default.
• W2059621062 hasBestOaLocation W20596210621 @default.
• W2059621062 hasConcept C104317684 @default.
• W2059621062 hasConcept C121608353 @default.
• W2059621062 hasConcept C126322002 @default.
• W2059621062 hasConcept C132538176 @default.
• W2059621062 hasConcept C142724271 @default.
• W2059621062 hasConcept C1491633281 @default.
• W2059621062 hasConcept C170493617 @default.
• W2059621062 hasConcept C204232928 @default.
• W2059621062 hasConcept C2776415932 @default.
• W2059621062 hasConcept C2778019345 @default.
• W2059621062 hasConcept C2779841796 @default.
• W2059621062 hasConcept C2781018059 @default.
• W2059621062 hasConcept C29537977 @default.
• W2059621062 hasConcept C502942594 @default.
• W2059621062 hasConcept C54355233 @default.
• W2059621062 hasConcept C55493867 @default.
• W2059621062 hasConcept C67082663 @default.
• W2059621062 hasConcept C71924100 @default.
• W2059621062 hasConcept C86803240 @default.
• W2059621062 hasConceptScore W2059621062C104317684 @default.
• W2059621062 hasConceptScore W2059621062C121608353 @default.
• W2059621062 hasConceptScore W2059621062C126322002 @default.
• W2059621062 hasConceptScore W2059621062C132538176 @default.
• W2059621062 hasConceptScore W2059621062C142724271 @default.
• W2059621062 hasConceptScore W2059621062C1491633281 @default.
• W2059621062 hasConceptScore W2059621062C170493617 @default.
• W2059621062 hasConceptScore W2059621062C204232928 @default.
• W2059621062 hasConceptScore W2059621062C2776415932 @default.
• W2059621062 hasConceptScore W2059621062C2778019345 @default.
• W2059621062 hasConceptScore W2059621062C2779841796 @default.
• W2059621062 hasConceptScore W2059621062C2781018059 @default.
• W2059621062 hasConceptScore W2059621062C29537977 @default.
• W2059621062 hasConceptScore W2059621062C502942594 @default.
• W2059621062 hasConceptScore W2059621062C54355233 @default.

• next