FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059624493> ?p ?o ?g. }

• W2059624493 endingPage "648" @default.
• W2059624493 startingPage "643" @default.
• W2059624493 abstract "epsilon-Crystallin occurs as an abundant lens protein in many birds and in crocodiles and has been identified as heart-type lactate dehydrogenase (LDH-B4). Lens proteins have, due to their longevity and environmental conditions, extraordinary requirements for structural stability. To study lens-protein stability, we compared various parameters of LDH-B4/epsilon-crystallin from lens and/or heart of duck, which has abundant amounts of this enzyme in its lenses, and of chicken and pig, which have no epsilon-crystallin. Measuring the thermostability of LDH-B4 from the different sources, the t50 values (temperature at which 50% of the enzyme activity remains after a 20-min period) for LDH-B4 from duck heart, duck lens and chicken heart were all found to be around 76 degrees C, whereas pig heart LDH-B4 was less thermostable, having a t50 value of 62.5 degrees C. A similar tendency was found with urea inactivation studies. Plotting the first-order rate constants obtained from inactivation kinetic plots against urea concentration, it was clear that LDH-B4 from pig heart was less stable in urea than the homologous enzymes from duck heart, chicken heart and duck lens. The duck and chicken enzymes were also much more resistant against proteolysis than the porcine enzyme. Therefore, it is concluded that avian LDH-B4 is structurally more stable than the homologous enzyme in mammals. This greater stability might make it suitable to function as a crystallin, as in duck, but is not necessarily associated with high lens expression, as in chicken." @default.
• W2059624493 created "2016-06-24" @default.
• W2059624493 creator A5009864943 @default.
• W2059624493 creator A5010329269 @default.
• W2059624493 creator A5032998470 @default.
• W2059624493 creator A5067559427 @default.
• W2059624493 creator A5075730057 @default.
• W2059624493 date "1993-02-01" @default.
• W2059624493 modified "2023-09-27" @default.
• W2059624493 title "Comparison of stability properties of lactate dehydrogenase B4/e-crystallin from different species" @default.
• W2059624493 cites W1515088892 @default.
• W2059624493 cites W1566157309 @default.
• W2059624493 cites W1606423922 @default.
• W2059624493 cites W1851093741 @default.
• W2059624493 cites W1966104409 @default.
• W2059624493 cites W1969915151 @default.
• W2059624493 cites W1983920529 @default.
• W2059624493 cites W1989469836 @default.
• W2059624493 cites W1990195842 @default.
• W2059624493 cites W1995047644 @default.
• W2059624493 cites W1996050139 @default.
• W2059624493 cites W1998533680 @default.
• W2059624493 cites W1999889695 @default.
• W2059624493 cites W2013729223 @default.
• W2059624493 cites W2022490019 @default.
• W2059624493 cites W2023997694 @default.
• W2059624493 cites W2035919478 @default.
• W2059624493 cites W2045430710 @default.
• W2059624493 cites W2055869444 @default.
• W2059624493 cites W2057594216 @default.
• W2059624493 cites W2066013441 @default.
• W2059624493 cites W2073368743 @default.
• W2059624493 cites W2076521338 @default.
• W2059624493 cites W2078383532 @default.
• W2059624493 cites W2080159499 @default.
• W2059624493 cites W2081618212 @default.
• W2059624493 cites W2083922038 @default.
• W2059624493 cites W2091612302 @default.
• W2059624493 cites W2091817414 @default.
• W2059624493 cites W2093969953 @default.
• W2059624493 cites W2100837269 @default.
• W2059624493 cites W2128223166 @default.
• W2059624493 cites W2129909236 @default.
• W2059624493 cites W2149858671 @default.
• W2059624493 cites W2346992656 @default.
• W2059624493 cites W2895899326 @default.
• W2059624493 cites W2975984604 @default.
• W2059624493 cites W41662802 @default.
• W2059624493 cites W4232534952 @default.
• W2059624493 cites W4239438559 @default.
• W2059624493 cites W4250518334 @default.
• W2059624493 doi "https://doi.org/10.1111/j.1432-1033.1993.tb17592.x" @default.
• W2059624493 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8436124" @default.
• W2059624493 hasPublicationYear "1993" @default.
• W2059624493 type Work @default.
• W2059624493 sameAs 2059624493 @default.
• W2059624493 citedByCount "8" @default.
• W2059624493 countsByYear W20596244932017 @default.
• W2059624493 crossrefType "journal-article" @default.
• W2059624493 hasAuthorship W2059624493A5009864943 @default.
• W2059624493 hasAuthorship W2059624493A5010329269 @default.
• W2059624493 hasAuthorship W2059624493A5032998470 @default.
• W2059624493 hasAuthorship W2059624493A5067559427 @default.
• W2059624493 hasAuthorship W2059624493A5075730057 @default.
• W2059624493 hasConcept C151730666 @default.
• W2059624493 hasConcept C15336307 @default.
• W2059624493 hasConcept C181199279 @default.
• W2059624493 hasConcept C185592680 @default.
• W2059624493 hasConcept C2777318727 @default.
• W2059624493 hasConcept C2780365088 @default.
• W2059624493 hasConcept C2781216036 @default.
• W2059624493 hasConcept C2781307694 @default.
• W2059624493 hasConcept C55493867 @default.
• W2059624493 hasConcept C7263354 @default.
• W2059624493 hasConcept C86803240 @default.
• W2059624493 hasConceptScore W2059624493C151730666 @default.
• W2059624493 hasConceptScore W2059624493C15336307 @default.
• W2059624493 hasConceptScore W2059624493C181199279 @default.
• W2059624493 hasConceptScore W2059624493C185592680 @default.
• W2059624493 hasConceptScore W2059624493C2777318727 @default.
• W2059624493 hasConceptScore W2059624493C2780365088 @default.
• W2059624493 hasConceptScore W2059624493C2781216036 @default.
• W2059624493 hasConceptScore W2059624493C2781307694 @default.
• W2059624493 hasConceptScore W2059624493C55493867 @default.
• W2059624493 hasConceptScore W2059624493C7263354 @default.
• W2059624493 hasConceptScore W2059624493C86803240 @default.
• W2059624493 hasIssue "3" @default.
• W2059624493 hasLocation W20596244931 @default.
• W2059624493 hasLocation W20596244932 @default.
• W2059624493 hasOpenAccess W2059624493 @default.
• W2059624493 hasPrimaryLocation W20596244931 @default.
• W2059624493 hasRelatedWork W117056335 @default.
• W2059624493 hasRelatedWork W1977438209 @default.
• W2059624493 hasRelatedWork W1983363658 @default.
• W2059624493 hasRelatedWork W2053834612 @default.
• W2059624493 hasRelatedWork W2059624493 @default.
• W2059624493 hasRelatedWork W2064127850 @default.
• W2059624493 hasRelatedWork W2096741276 @default.

• next