FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059632209> ?p ?o ?g. }

• W2059632209 endingPage "582" @default.
• W2059632209 startingPage "574" @default.
• W2059632209 abstract "Abstract Objective: The origin of neural hyperexcitability underlying idiopathic generalized epilepsy (IGE) is not known. The objective of this study is to identify evidence of hyperexcitability in precisely measured visual evoked responses and to understand the nature of changes in excitation and inhibition that lead to altered responses in human patients with IGE. Methods: Steady‐state visual‐evoked potentials (VEPs) to contrast reversing gratings were recorded over a wide range of stimulus contrast. VEPs were analyzed at the pattern reversal rate using spectral analysis. Ten patients with IGE and 13 healthy subjects participated. All subjects had normal visual acuity and had no history of photic‐induced seizures or photoparoxysmal electroencephalograph (EEG) activity. Results: At a group level, the amplitude of visual responses did not saturate at high stimulus contrast in patients, as it did in the control subjects. This reflects an abnormality in neuronal gain control. The VEPs did not have sufficient power to reliably distinguish patients from controls at an individual level. Parametric modeling using a standard gain control framework showed that the abnormality lay in reduced inhibition from neighboring neurons rather than increased excitatory response to the stimulus. Interpretation: Visual evoked responses reveal changes in a fundamental mechanism regulating neuronal sensitivity. These changes may give rise to hyperexcitability underlying generalized epilepsy. ANN NEUROL 2011;" @default.
• W2059632209 created "2016-06-24" @default.
• W2059632209 creator A5022000443 @default.
• W2059632209 creator A5033028925 @default.
• W2059632209 creator A5035569274 @default.
• W2059632209 creator A5046794552 @default.
• W2059632209 date "2011-06-27" @default.
• W2059632209 modified "2023-10-18" @default.
• W2059632209 title "Contrast gain control abnormalities in idiopathic generalized epilepsy" @default.
• W2059632209 cites W1483072356 @default.
• W2059632209 cites W1809188141 @default.
• W2059632209 cites W1920704151 @default.
• W2059632209 cites W1936556066 @default.
• W2059632209 cites W1971002207 @default.
• W2059632209 cites W1972864926 @default.
• W2059632209 cites W1975440733 @default.
• W2059632209 cites W1977851999 @default.
• W2059632209 cites W1982488885 @default.
• W2059632209 cites W1984250080 @default.
• W2059632209 cites W1990308283 @default.
• W2059632209 cites W1996220863 @default.
• W2059632209 cites W2002189290 @default.
• W2059632209 cites W2006495734 @default.
• W2059632209 cites W2012588554 @default.
• W2059632209 cites W2015378456 @default.
• W2059632209 cites W2020222647 @default.
• W2059632209 cites W2021281924 @default.
• W2059632209 cites W2023283085 @default.
• W2059632209 cites W2024609857 @default.
• W2059632209 cites W2025636960 @default.
• W2059632209 cites W2025714675 @default.
• W2059632209 cites W2038718814 @default.
• W2059632209 cites W2039251595 @default.
• W2059632209 cites W2044932255 @default.
• W2059632209 cites W2046340161 @default.
• W2059632209 cites W2072668509 @default.
• W2059632209 cites W2076329843 @default.
• W2059632209 cites W2088366833 @default.
• W2059632209 cites W2092270366 @default.
• W2059632209 cites W2097882735 @default.
• W2059632209 cites W2105423985 @default.
• W2059632209 cites W2105458646 @default.
• W2059632209 cites W2113533823 @default.
• W2059632209 cites W2116079555 @default.
• W2059632209 cites W2121584771 @default.
• W2059632209 cites W2123946839 @default.
• W2059632209 cites W2128105404 @default.
• W2059632209 cites W2129526809 @default.
• W2059632209 cites W2135962619 @default.
• W2059632209 cites W2148165961 @default.
• W2059632209 cites W2149166988 @default.
• W2059632209 cites W2150294643 @default.
• W2059632209 cites W2159432306 @default.
• W2059632209 cites W2162901954 @default.
• W2059632209 cites W2167395832 @default.
• W2059632209 cites W2170319235 @default.
• W2059632209 cites W3106889297 @default.
• W2059632209 cites W4239594659 @default.
• W2059632209 doi "https://doi.org/10.1002/ana.22462" @default.
• W2059632209 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3183388" @default.
• W2059632209 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21710621" @default.
• W2059632209 hasPublicationYear "2011" @default.
• W2059632209 type Work @default.
• W2059632209 sameAs 2059632209 @default.
• W2059632209 citedByCount "22" @default.
• W2059632209 countsByYear W20596322092013 @default.
• W2059632209 countsByYear W20596322092014 @default.
• W2059632209 countsByYear W20596322092015 @default.
• W2059632209 countsByYear W20596322092016 @default.
• W2059632209 countsByYear W20596322092017 @default.
• W2059632209 countsByYear W20596322092019 @default.
• W2059632209 countsByYear W20596322092021 @default.
• W2059632209 countsByYear W20596322092022 @default.
• W2059632209 crossrefType "journal-article" @default.
• W2059632209 hasAuthorship W2059632209A5022000443 @default.
• W2059632209 hasAuthorship W2059632209A5033028925 @default.
• W2059632209 hasAuthorship W2059632209A5035569274 @default.
• W2059632209 hasAuthorship W2059632209A5046794552 @default.
• W2059632209 hasBestOaLocation W20596322092 @default.
• W2059632209 hasConcept C15744967 @default.
• W2059632209 hasConcept C169760540 @default.
• W2059632209 hasConcept C180747234 @default.
• W2059632209 hasConcept C185263204 @default.
• W2059632209 hasConcept C2777295592 @default.
• W2059632209 hasConcept C2778186239 @default.
• W2059632209 hasConcept C2779918689 @default.
• W2059632209 hasConcept C2779979230 @default.
• W2059632209 hasConcept C3018323323 @default.
• W2059632209 hasConcept C50965678 @default.
• W2059632209 hasConcept C522805319 @default.
• W2059632209 hasConcept C548259974 @default.
• W2059632209 hasConcept C71924100 @default.
• W2059632209 hasConcept C77805123 @default.
• W2059632209 hasConceptScore W2059632209C15744967 @default.
• W2059632209 hasConceptScore W2059632209C169760540 @default.
• W2059632209 hasConceptScore W2059632209C180747234 @default.
• W2059632209 hasConceptScore W2059632209C185263204 @default.
• W2059632209 hasConceptScore W2059632209C2777295592 @default.

• next